Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
SGK-Sanofi-14i C18H15ClN6O3S 430,.87 SGK Halland, N (2015) ACS Medicinal Chemistry Letters 6 73-78 Download

Results as Barchart

View results as a bar chart
1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 99 5
MKK2 90 9
MKK6 94 5
ERK1 99 3
ERK2 99 2
ERK5 101 7
JNK1 91 14
JNK2 106 2
JNK3 99 3
p38 alpha MAPK 98 9
p38 beta MAPK 91 8
p38 gamma MAPK 105 0
p38 delta MAPK 94 11
ERK8 40 2
RSK1 94 1
RSK2 92 0
PDK1 112 16
PKB alpha 104 4
PKB beta 101 7
SGK1 4 0
S6K1 5 0
PKA 101 2
ROCK 2 96 11
PRK2 99 14
PKC alpha 108 9
PKC gamma 97 5
PKC zeta 101 9
PKD1 88 1
STK33 102 9
MSK1 30 10
MNK1 84 10
MNK2 116 13
MAPKAP-K2 97 15
MAPKAP-K3 101 5
PRAK 97 3
CAMKK beta 117 7
CAMK1 66 8
SmMLCK 93 3
PHK 122 6
DAPK1 103 10
CHK1 73 1
CHK2 75 13
GSK3 beta 104 1
CDK2-Cyclin A 85 2
CDK9-Cyclin T1 111 4
PLK1 96 1
Aurora A 111 4
Aurora B 87 22
TLK1 82 3
LKB1 117 5
AMPK (hum) 83 7
MARK1 116 14
MARK2 92 4
MARK3 103 9
MARK4 86 6
BRSK1 100 1
BRSK2 87 15
MELK 81 4
NUAK1 65 3
SIK2 107 15
SIK3 107 15
TSSK1 103 11
CK1 gamma 2 98 15
CK1 delta 116 9
CK2 87 4
TTBK1 112 7
TTBK2 124 15
DYRK1A 98 2
DYRK2 123 1
DYRK3 90 45
NEK2a 109 7
NEK6 100 11
IKK beta 105 8
IKK epsilon 83 12
TBK1 61 34
PIM1 105 5
PIM2 134 2
PIM3 104 12
SRPK1 107 10
EF2K 107 22
EIF2AK3 80 15
HIPK1 78 2
HIPK2 15 3
HIPK3 47 4
CLK2 97 12
PAK2 100 8
PAK4 32 2
PAK5 68 5
PAK6 98 2
MST2 108 5
MST3 102 7
MST4 67 19
GCK 40 0
MAP4K3 66 11
MAP4K5 39 3
MINK1 68 3
MEKK1 92 4
MLK1 24 2
MLK3 11 1
TESK1 105 19
TAO1 75 4
ASK1 98 5
TAK1 63 7
IRAK1 80 16
IRAK4 113 5
RIPK2 94 3
OSR1 110 15
TTK 70 14
MPSK1 113 7
WNK1 97 1
ULK1 98 8
ULK2 97 6
TGFBR1 118 2
Src 121 6
Lck 88 4
CSK 84 10
YES1 95 2
ABL 104 15
BTK 92 1
JAK2 81 7
SYK 84 26
ZAP70 112 9
TIE2 9 0
BRK 111 6
EPH-A2 98 2
EPH-A4 98 8
EPH-B1 97 19
EPH-B2 97 12
EPH-B3 98 4
EPH-B4 98 11
FGF-R1 92 10
HER4 94 12
IGF-1R 119 5
IR 111 25
IRR 91 6
TrkA 79 19
DDR2 103 0
VEGFR1 68 7
PDGFRA 55 9
PINK 98 21

Do you need any help? Please get in touch and we’ll be happy to lend a hand.