Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
SGK1-Sanofi-14g C17H12Cl2N6O2S 435.29 SGK Halland, N (2015) ACS Medicinal Chemistry Letters 6 73-78 Download

Results as Barchart

View results as a bar chart
1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 101 2
MKK2 97 11
MKK6 101 13
ERK1 81 16
ERK2 105 0
ERK5 102 5
JNK1 100 2
JNK2 98 2
JNK3 108 10
p38 alpha MAPK 114 0
p38 beta MAPK 98 19
p38 gamma MAPK 101 28
p38 delta MAPK 89 26
ERK8 34 8
RSK1 75 5
RSK2 85 1
PDK1 116 2
PKB alpha 100 11
PKB beta 98 2
SGK1 4 0
S6K1 9 0
PKA 94 11
ROCK 2 89 9
PRK2 119 2
PKC alpha 118 0
PKC gamma 116 16
PKC zeta 98 15
PKD1 86 6
STK33 101 17
MSK1 57 10
MNK1 102 4
MNK2 110 4
MAPKAP-K2 115 17
MAPKAP-K3 127 5
PRAK 107 1
CAMKK beta 110 19
CAMK1 42 15
SmMLCK 101 4
PHK 125 2
DAPK1 91 12
CHK1 79 3
CHK2 79 2
GSK3 beta 111 16
CDK2-Cyclin A 92 25
CDK9-Cyclin T1 101 19
PLK1 104 5
Aurora A 102 22
Aurora B 99 7
TLK1 90 11
LKB1 100 1
AMPK (hum) 94 4
MARK1 112 16
MARK2 86 27
MARK3 100 7
MARK4 102 7
BRSK1 112 1
BRSK2 83 33
MELK 79 19
NUAK1 70 7
SIK2 125 28
SIK3 115 4
TSSK1 102 10
CK1 gamma 2 113 0
CK1 delta 123 8
CK2 96 8
TTBK1 114 28
TTBK2 124 7
DYRK1A 97 3
DYRK2 130 8
DYRK3 110 15
NEK2a 113 3
NEK6 107 4
IKK beta 107 18
IKK epsilon 76 7
TBK1 84 8
PIM1 113 0
PIM2 117 32
PIM3 101 56
SRPK1 118 19
EF2K 110 5
EIF2AK3 120 6
HIPK1 100 3
HIPK2 54 3
HIPK3 88 2
CLK2 116 18
PAK2 109 7
PAK4 39 6
PAK5 85 1
PAK6 99 2
MST2 116 11
MST3 95 17
MST4 99 8
GCK 66 0
MAP4K3 67 9
MAP4K5 39 2
MINK1 77 28
MEKK1 98 17
MLK1 28 7
MLK3 15 4
TESK1 107 6
TAO1 96 17
ASK1 103 0
TAK1 79 3
IRAK1 85 42
IRAK4 112 4
RIPK2 117 10
OSR1 115 3
TTK 81 16
MPSK1 104 11
WNK1 114 4
ULK1 105 8
ULK2 90 18
TGFBR1 113 1
Src 107 5
Lck 95 7
CSK 85 12
YES1 94 14
ABL 107 13
BTK 92 15
JAK2 113 3
SYK 106 11
ZAP70 118 24
TIE2 15 4
BRK 99 20
EPH-A2 94 18
EPH-A4 120 4
EPH-B1 99 7
EPH-B2 113 23
EPH-B3 108 3
EPH-B4 109 9
FGF-R1 113 24
HER4 105 21
IGF-1R 121 5
IR 120 6
IRR 92 29
TrkA 93 14
DDR2 113 5
VEGFR1 104 26
PDGFRA 108 1
PINK 103 23

Do you need any help? Please get in touch and we’ll be happy to lend a hand.