Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
QNZ C22H20N4O 356.4 NF-κB Cayman Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 94 6
MKK2 72 7
MKK6 97 11
ERK1 85 0
ERK2 91 4
ERK5 99 3
JNK1 86 5
JNK2 95 10
JNK3 80 3
p38 alpha MAPK 95 17
p38 beta MAPK 105 6
p38 gamma MAPK 101 7
p38 delta MAPK 84 11
ERK8 86 8
RSK1 88 9
RSK2 71 6
PDK1 104 4
PKB alpha 93 8
PKB beta 92 2
SGK1 88 2
S6K1 91 10
PKA 90 2
ROCK 2 73 3
PRK2 86 14
PKC alpha 100 4
PKC gamma 98 27
PKC zeta 86 4
PKD1 86 4
STK33 93 2
MSK1 92 14
MNK1 114 5
MNK2 85 5
MAPKAP-K2 107 18
MAPKAP-K3 91 1
PRAK 87 7
CAMKK beta 86 1
CAMK1 82 3
SmMLCK 84 11
PHK 80 2
DAPK1 90 1
CHK1 78 13
CHK2 44 2
GSK3 beta 90 4
CDK2-Cyclin A 100 6
CDK9-Cyclin T1 99 8
PLK1 100 4
Aurora A 107 8
Aurora B 60 15
TLK1 85 7
LKB1 104 13
AMPK (hum) 112 23
MARK1 87 3
MARK2 91 8
MARK3 87 15
MARK4 76 7
BRSK1 112 6
BRSK2 87 14
MELK 91 3
NUAK1 103 10
SIK2 76 7
SIK3 74 15
TSSK1 86 7
CK1 gamma 2 108 4
CK1 delta 97 6
CK2 97 0
TTBK1 93 12
TTBK2 124 10
DYRK1A 82 2
DYRK2 88 2
DYRK3 100 5
NEK2a 89 4
NEK6 111 5
IKK beta 72 13
IKK epsilon 87 8
TBK1 102 10
PIM1 93 4
PIM2 88 8
PIM3 77 0
SRPK1 98 9
EF2K 98 7
EIF2AK3 99 1
HIPK1 98 7
HIPK2 99 6
HIPK3 74 4
CLK2 88 2
PAK2 75 0
PAK4 86 14
PAK5 86 7
PAK6 92 6
MST2 103 3
MST3 98 10
MST4 118 2
GCK 64 8
MAP4K3 95 19
MAP4K5 38 13
MINK1 101 12
MEKK1 75 16
MLK1 57 4
MLK3 63 5
TESK1 97 14
TAO1 101 9
ASK1 122 8
TAK1 79 5
IRAK1 87 16
IRAK4 72 3
RIPK2 85 0
OSR1 108 12
TTK 76 2
MPSK1 102 10
WNK1 95 4
ULK1 103 8
ULK2 91 1
TGFBR1 103 2
Src 50 2
Lck 72 6
CSK 84 1
YES1 65 3
ABL 114 3
BTK 91 6
JAK2 85 3
SYK 89 1
ZAP70 102 6
TIE2 88 2
BRK 73 10
EPH-A2 104 1
EPH-A4 98 17
EPH-B1 95 9
EPH-B2 106 18
EPH-B3 110 21
EPH-B4 105 2
FGF-R1 96 0
HER4 16 2
IGF-1R 91 17
IR 102 23
IRR 100 0
TrkA 81 9
DDR2 98 11
VEGFR1 88 7
PDGFRA 84 4
PINK 94 11
Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 119 13
MKK2 75 14
MKK6 92 5
ERK1 100 3
ERK2 107 4
ERK5 99 6
JNK1 79 10
JNK2 97 1
JNK3 93 11
p38 alpha MAPK 100 23
p38 beta MAPK 106 1
p38 gamma MAPK 106 1
p38 delta MAPK 98 16
ERK8 99 4
RSK1 99 2
RSK2 85 14
PDK1 105 17
PKB alpha 109 7
PKB beta 87 1
SGK1 99 28
S6K1 109 10
PKA 107 4
ROCK 2 87 1
PRK2 115 5
PKC alpha 98 7
PKC gamma 79 22
PKC zeta 94 7
PKD1 105 15
STK33 101 2
MSK1 92 16
MNK1 112 6
MNK2 96 6
MAPKAP-K2 108 4
MAPKAP-K3 97 5
PRAK 96 7
CAMKK beta 99 4
CAMK1 101 14
SmMLCK 102 19
PHK 95 9
DAPK1 104 17
CHK1 87 8
CHK2 81 3
GSK3 beta 87 10
CDK2-Cyclin A 114 11
CDK9-Cyclin T1 82 9
PLK1 106 5
Aurora A 100 12
Aurora B 88 14
TLK1 100 1
LKB1 87 8
AMPK (hum) 114 8
MARK1 89 2
MARK2 98 2
MARK3 110 38
MARK4 90 3
BRSK1 111 9
BRSK2 86 7
MELK 86 13
NUAK1 96 5
SIK2 101 8
SIK3 88 9
TSSK1 94 6
CK1 gamma 2 98 1
CK1 delta 93 2
CK2 97 2
TTBK1 84 8
TTBK2 119 39
DYRK1A 88 2
DYRK2 89 3
DYRK3 101 15
NEK2a 89 5
NEK6 98 4
IKK beta 94 7
IKK epsilon 92 3
TBK1 114 4
PIM1 94 7
PIM2 101 2
PIM3 103 8
SRPK1 95 9
EF2K 115 4
EIF2AK3 97 8
HIPK1 96 13
HIPK2 95 7
HIPK3 125 1
CLK2 101 18
PAK2 89 5
PAK4 94 10
PAK5 102 10
PAK6 89 3
MST2 110 5
MST3 96 13
MST4 99 6
GCK 102 2
MAP4K3 103 25
MAP4K5 100 2
MINK1 118 11
MEKK1 86 26
MLK1 84 6
MLK3 98 16
TESK1 111 34
TAO1 102 5
ASK1 135 25
TAK1 90 3
IRAK1 94 4
IRAK4 93 0
RIPK2 104 4
OSR1 107 8
TTK 86 6
MPSK1 102 4
WNK1 98 4
ULK1 111 2
ULK2 102 4
TGFBR1 106 14
Src 74 10
Lck 63 33
CSK 96 6
YES1 97 5
ABL 111 4
BTK 88 10
JAK2 93 9
SYK 105 7
ZAP70 134 5
TIE2 109 11
BRK 99 7
EPH-A2 90 7
EPH-A4 102 11
EPH-B1 96 25
EPH-B2 104 0
EPH-B3 98 10
EPH-B4 113 11
FGF-R1 106 5
HER4 23 10
IGF-1R 119 32
IR 89 3
IRR 122 2
TrkA 139 47
DDR2 112 4
VEGFR1 96 13
PDGFRA 93 8
PINK 106 5

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