Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Crenolanib C26H29N5O2 443.5 FLT3 Smith CC (2014 )Proc Natl Acad Sci U S A Apr 8 111(14) 5319-24 Download

Results as Barchart

View results as a bar chart
1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
MAP4K3 0 0
PHK 1 0
MLK1 2 1
AMPK (hum) 2 1
TrkA 2 0
CAMKK beta 3 0
NUAK1 4 0
ULK2 4 1
MLK3 4 1
MST2 5 1
VEGFR1 5 1
PRK2 5 1
CDK2-Cyclin A 6 1
SIK2 6 3
MAP4K5 6 1
MARK3 8 2
RIPK2 10 0
PDGFRA 10 1
ERK8 10 1
DDR2 10 3
SIK3 11 11
CDK9-Cyclin T1 12 2
GCK 13 4
RSK1 14 1
MARK1 14 1
MNK2 16 1
MINK1 17 1
Lck 21 4
Aurora B 23 6
MARK4 24 3
YES1 26 3
IRAK4 28 5
BRSK1 30 0
DYRK1A 31 1
MARK2 31 0
MKK2 32 2
MELK 34 6
MNK1 35 4
ULK1 36 8
ROCK 2 36 3
MKK1 39 0
MST3 41 2
TAK1 41 9
BRSK2 41 4
ABL 45 1
TSSK1 46 3
RSK2 46 4
DYRK3 47 2
IRAK1 48 3
CLK2 49 8
TAO1 52 2
TBK1 55 7
ERK5 57 1
CAMK1 58 0
MSK1 60 1
PIM1 61 7
PAK4 61 12
PKD1 66 2
JAK2 66 4
EPH-A4 69 10
LKB1 72 5
Src 72 7
TTK 75 18
FGF-R1 77 3
CHK1 77 4
PKC alpha 78 8
SGK1 80 4
S6K1 80 4
IRR 80 6
CSK 81 7
PAK5 81 1
CK1 gamma 2 85 14
EPH-A2 86 7
IKK epsilon 87 6
PIM3 87 1
SYK 87 13
PKC gamma 89 5
MEKK1 89 2
HIPK2 90 10
JNK3 90 14
MST4 91 0
PIM2 91 4
p38 alpha MAPK 92 6
TIE2 92 0
STK33 93 18
NEK6 93 5
PDK1 94 2
MKK6 94 6
GSK3 beta 95 12
DAPK1 95 15
EPH-B2 96 10
PAK2 96 2
IR 97 17
EPH-B4 98 9
PRAK 98 0
ERK2 98 7
EPH-B3 99 4
JNK2 99 4
CK1 delta 100 10
CK2 100 2
JNK1 100 7
IKK beta 100 7
HIPK3 101 15
PAK6 101 11
SRPK1 102 3
SmMLCK 102 8
DYRK2 103 9
p38 gamma MAPK 104 1
PLK1 104 6
PKB alpha 104 12
ERK1 105 10
PKA 105 8
Aurora A 106 5
CHK2 107 4
ZAP70 107 5
p38 delta MAPK 107 5
TTBK1 107 4
TTBK2 107 0
MPSK1 108 22
TLK1 108 8
HER4 108 11
ASK1 108 3
OSR1 109 11
WNK1 109 7
EF2K 109 5
HIPK1 109 0
EPH-B1 110 5
BRK 111 19
IGF-1R 111 8
MAPKAP-K2 112 4
EIF2AK3 112 2
BTK 113 3
PKC zeta 115 12
NEK2a 117 4
p38 beta MAPK 118 1
MAPKAP-K3 120 14
PKB beta 120 30
PINK 122 8
TGFBR1 133 15
TESK1 146 16

Do you need any help? Please get in touch and we’ll be happy to lend a hand.