Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Dasatinib C22H26ClN7O2S 487 BCR-ABL, Src Kantarjian H. N Engl J Med. (2010) 2260-70 WO2009094556 Cayman Chemical Download

Results as Barchart

View results as a bar chart
1µM
0.1µM

Results as Table

Screening Concentration: 0.1µM
Kinase % Activity Remainingsort descending Standard Deviation
EPH-B1 -1 1
ABL 0 0
YES1 1 0
BTK 1 0
DDR2 1 1
EPH-A2 1 0
EPH-B2 1 0
EPH-B3 1 0
Src 1 0
Lck 1 0
EPH-A4 2 0
SIK2 4 1
RIPK2 5 0
BRK 5 0
PDGFRA 6 1
SIK3 9 2
EPH-B4 20 0
MAP4K5 22 1
HER4 27 1
TESK1 50 3
MLK1 72 1
MST2 75 2
MLK3 76 10
VEGFR1 78 9
p38 alpha MAPK 79 15
RSK2 86 9
SGK1 87 11
ERK5 87 2
TIE2 88 7
MAP4K3 88 15
FGF-R1 88 7
CAMK1 89 16
IRR 89 4
PIM1 90 1
ERK8 90 14
MINK1 90 4
ERK1 91 6
PKD1 92 21
ERK2 93 9
JAK2 94 2
MSK1 94 4
Aurora A 94 0
PDK1 94 9
PKB beta 94 11
GCK 95 7
ULK1 95 9
CK2 95 3
HIPK2 95 1
CAMKK beta 96 4
MARK3 96 16
IRAK1 96 1
PIM3 96 8
TLK1 96 4
LKB1 96 18
CSK 97 19
TAK1 97 23
IKK beta 97 21
SYK 97 1
MST4 97 10
MNK2 97 8
DYRK3 98 7
PKC alpha 98 3
CHK2 98 8
MEKK1 98 4
IR 99 2
PRK2 100 2
CHK1 100 6
TBK1 100 1
OSR1 100 1
p38 gamma MAPK 100 4
DYRK2 101 5
PHK 101 10
PKC zeta 101 3
MPSK1 101 5
ULK2 101 3
HIPK3 102 3
BRSK2 102 14
IKK epsilon 102 5
GSK3 beta 103 2
TGFBR1 103 1
PKB alpha 103 15
TTK 104 6
PIM2 104 3
WNK1 104 4
SRPK1 104 9
EF2K 104 4
MKK6 104 11
MARK4 105 12
p38 beta MAPK 105 11
STK33 105 6
RSK1 105 2
HIPK1 105 4
TSSK1 106 11
EIF2AK3 106 6
IGF-1R 107 6
TrkA 107 11
PKC gamma 107 22
AMPK (hum) 107 13
S6K1 108 3
ASK1 108 7
JNK1 108 4
JNK3 108 0
MNK1 108 0
ZAP70 109 1
PKA 110 12
JNK2 110 10
TTBK2 110 5
DYRK1A 111 4
SmMLCK 111 4
IRAK4 112 24
MELK 112 7
TTBK1 112 8
NEK6 113 4
CK1 delta 113 4
MKK2 113 11
MST3 114 20
MAPKAP-K2 114 4
MARK1 115 3
CK1 gamma 2 115 0
CDK2-Cyclin A 116 1
PINK 117 1
MAPKAP-K3 117 3
MARK2 118 4
PAK2 118 2
p38 delta MAPK 118 17
MKK1 118 10
NUAK1 119 10
CLK2 120 6
TAO1 120 9
Aurora B 120 10
NEK2a 122 11
CDK9-Cyclin T1 122 8
DAPK1 126 10
BRSK1 126 0
PAK6 126 9
PRAK 129 14
ROCK 2 130 10
PAK5 131 12
PLK1 133 18
PAK4 137 21
Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
EPH-B1 -1 2
ABL 0 0
DDR2 0 0
EPH-B2 1 0
EPH-B3 1 0
Lck 1 0
YES1 1 0
BTK 1 0
EPH-A2 1 0
Src 2 0
SIK2 2 1
BRK 2 0
SIK3 2 0
EPH-A4 2 2
EPH-B4 3 0
PDGFRA 3 1
MAP4K5 3 1
HER4 6 0
TESK1 8 0
CSK 8 3
RIPK2 10 12
p38 alpha MAPK 29 2
MLK3 39 6
MLK1 41 2
JAK2 42 1
p38 beta MAPK 44 4
MINK1 51 1
VEGFR1 53 4
MAP4K3 54 1
GCK 56 8
CAMK1 77 1
MST4 77 4
TIE2 78 5
CK2 80 28
MST2 81 6
TGFBR1 82 5
FGF-R1 84 6
TrkA 88 2
IRR 90 14
SYK 90 0
ULK2 91 3
MKK2 91 0
ERK5 91 4
PDK1 92 1
MST3 93 2
PKB beta 94 2
IR 94 7
EF2K 95 5
TAO1 95 7
ERK8 95 11
SGK1 96 7
CHK1 96 6
HIPK2 97 5
TBK1 97 10
IGF-1R 98 7
NEK2a 98 4
PIM1 98 1
CAMKK beta 99 19
TAK1 99 7
IKK beta 99 9
PLK1 99 15
LKB1 100 14
RSK2 101 3
PRK2 101 0
OSR1 101 0
Aurora A 101 1
ULK1 101 0
MEKK1 102 1
ERK2 102 1
DAPK1 102 7
IRAK4 102 6
CHK2 102 1
RSK1 102 5
MNK1 102 9
PHK 103 1
MSK1 103 1
MARK3 104 5
DYRK3 104 9
WNK1 104 12
PKC alpha 105 14
p38 gamma MAPK 105 7
PIM2 105 1
MNK2 106 2
PKD1 107 15
SRPK1 107 9
Aurora B 108 10
IRAK1 108 3
BRSK2 108 13
PIM3 108 5
PKC zeta 109 7
TTK 109 9
STK33 110 4
MAPKAP-K2 111 7
SmMLCK 111 7
TTBK1 112 1
MKK6 112 4
CDK2-Cyclin A 112 1
EIF2AK3 113 2
HIPK3 113 7
S6K1 113 11
JNK3 113 15
TSSK1 113 3
CK1 gamma 2 113 12
ERK1 114 12
PKC gamma 114 22
MARK4 115 24
TTBK2 117 7
DYRK2 117 9
ASK1 118 7
NUAK1 118 8
PAK2 119 12
PKB alpha 120 13
AMPK (hum) 120 5
PAK6 120 4
CLK2 121 6
PKA 121 27
JNK1 121 9
ZAP70 121 27
GSK3 beta 121 12
HIPK1 122 6
BRSK1 123 1
NEK6 123 6
IKK epsilon 123 13
MPSK1 123 1
CK1 delta 124 1
TLK1 124 0
JNK2 125 0
DYRK1A 126 19
MARK2 126 2
MARK1 127 3
PRAK 128 7
MELK 128 7
MAPKAP-K3 132 1
ROCK 2 132 7
PAK4 132 16
PINK 133 5
p38 delta MAPK 133 1
MKK1 134 16
PAK5 138 7
CDK9-Cyclin T1 138 12

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