Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
BX-912 C20H23BrN8O 471.35 PDK Feldman RI. (2005) J. Biol. Chem. 2005 May 20 280(20) 19867-74 Axon Download

Results as Barchart

View results as a bar chart
0.1µM
1µM

Results as Table

Screening Concentration: 0.1µM
Kinase % Activity Remainingsort ascending Standard Deviation
MPSK1 121 1
PIM3 113 3
WNK1 112 6
PRAK 112 8
IKK beta 111 6
PKC gamma 110 3
PKC zeta 109 21
EPH-B1 109 1
TTBK2 109 25
PLK1 106 10
MAPKAP-K3 106 6
PIM1 105 1
PIM2 105 4
EPH-B3 104 5
EPH-B4 104 4
PAK6 104 21
CK2 103 11
TESK1 102 13
JNK1 102 13
ROCK 2 102 5
IRR 102 12
DYRK2 101 5
PHK 101 6
NEK2a 101 13
NEK6 101 1
JNK3 101 4
ZAP70 100 3
OSR1 100 12
EPH-A2 100 5
MSK1 100 8
DAPK1 100 2
IRAK1 100 1
p38 delta MAPK 99 33
CK1 gamma 2 99 14
DYRK3 99 5
PAK2 99 7
EPH-A4 98 14
MNK1 97 17
MAPKAP-K2 97 9
EIF2AK3 97 1
p38 alpha MAPK 96 17
SRPK1 96 3
ASK1 96 2
TTK 95 10
MNK2 95 4
TLK1 95 10
Lck 95 16
MEKK1 94 6
TTBK1 94 3
PKB beta 94 10
HIPK3 94 4
HER4 94 9
EPH-B2 93 11
CSK 93 9
CAMK1 93 11
PAK4 93 3
JNK2 93 1
p38 beta MAPK 92 3
CK1 delta 92 3
HIPK2 92 1
EF2K 91 24
ULK2 91 9
BTK 91 7
BRK 89 0
Src 89 3
ERK2 89 3
PAK5 89 9
DDR2 89 5
ERK1 88 3
SmMLCK 88 13
GSK3 beta 87 15
TGFBR1 87 6
PKB alpha 87 1
HIPK1 87 14
SGK1 87 1
ABL 87 7
p38 gamma MAPK 86 5
CDK9-Cyclin T1 86 6
TIE2 85 2
PINK 84 2
DYRK1A 84 8
ERK5 83 2
RSK1 82 16
CLK2 82 1
YES1 82 7
IR 82 25
PKC alpha 82 6
PKD1 81 1
TAO1 81 2
S6K1 80 2
IGF-1R 80 3
MST3 79 5
LKB1 79 4
MST4 77 4
STK33 76 4
MAP4K3 75 6
MKK6 74 12
SYK 74 16
MINK1 73 7
MELK 72 8
MAP4K5 70 2
TSSK1 69 11
PKA 69 6
RIPK2 68 4
PRK2 68 3
CHK2 67 5
PDGFRA 65 1
CAMKK beta 65 2
MKK1 63 3
IKK epsilon 62 1
Aurora A 62 9
RSK2 62 11
MKK2 57 5
MST2 56 0
CDK2-Cyclin A 50 1
CHK1 50 3
BRSK2 50 6
FGF-R1 49 6
TAK1 49 1
ULK1 48 6
TBK1 45 5
BRSK1 44 1
PDK1 43 9
SIK3 42 2
ERK8 42 5
MARK2 42 5
IRAK4 42 1
MARK1 41 4
TrkA 40 4
GCK 39 7
MARK4 32 5
AMPK (hum) 28 1
JAK2 27 0
MARK3 18 1
MLK1 16 0
MLK3 11 1
VEGFR1 10 0
SIK2 9 0
Aurora B 7 2
NUAK1 2 0
Screening Concentration: 1µM
Kinase % Activity Remainingsort ascending Standard Deviation
PKC zeta 118 6
EPH-B1 110 5
PIM1 105 5
PIM2 105 15
MPSK1 105 2
PIM3 104 3
WNK1 104 4
EPH-B4 104 10
MAPKAP-K2 103 13
EF2K 101 30
TTBK1 101 5
PRAK 101 8
EPH-B3 99 6
MAPKAP-K3 98 4
MEKK1 97 1
SRPK1 96 13
NEK6 95 17
EIF2AK3 94 5
IKK beta 94 3
TESK1 93 5
TGFBR1 92 6
TLK1 91 0
PKB beta 91 11
p38 alpha MAPK 91 3
HIPK2 90 9
TTBK2 89 6
CAMK1 89 9
OSR1 89 4
CSK 88 9
ZAP70 88 2
PINK 88 4
CK1 delta 87 3
PAK2 87 20
PAK6 87 10
EPH-A2 87 9
EPH-A4 86 3
PKC gamma 86 12
p38 beta MAPK 85 3
CK1 gamma 2 84 4
p38 gamma MAPK 84 3
DYRK3 83 3
NEK2a 82 13
PKB alpha 81 3
HIPK3 81 1
GSK3 beta 81 0
CK2 80 4
SmMLCK 80 5
MNK1 79 2
EPH-B2 79 4
DYRK2 79 1
PLK1 77 17
DAPK1 76 9
JNK3 76 0
TTK 76 5
DYRK1A 75 8
ROCK 2 75 2
MSK1 74 11
JNK1 74 7
IRR 73 6
PAK5 73 4
PKC alpha 73 20
p38 delta MAPK 72 4
HER4 69 21
DDR2 69 4
ERK1 67 5
HIPK1 63 7
ERK2 63 1
ERK5 63 8
SGK1 60 2
CDK9-Cyclin T1 60 7
JNK2 59 1
TIE2 58 13
MKK6 56 7
PAK4 54 4
Src 53 5
MINK1 52 10
S6K1 52 4
LKB1 49 6
MST3 49 3
PHK 48 0
IRAK1 48 5
MST4 48 3
RIPK2 47 2
TAO1 46 8
ASK1 46 1
TSSK1 45 5
RSK2 45 4
MNK2 45 2
IGF-1R 45 4
Lck 43 3
RSK1 42 0
ULK2 42 4
YES1 42 8
BTK 40 7
BRK 39 2
PKD1 37 1
MAP4K5 35 2
ABL 35 0
IR 34 7
STK33 33 6
PRK2 32 4
MST2 31 2
PKA 30 1
MELK 30 3
PDGFRA 29 5
CLK2 26 0
IKK epsilon 24 1
SYK 21 4
MKK1 20 3
MKK2 20 3
MAP4K3 18 2
CAMKK beta 18 0
CHK2 18 2
TrkA 17 5
ULK1 15 1
TAK1 15 2
Aurora A 14 3
CHK1 14 0
BRSK2 13 0
MARK2 12 2
BRSK1 12 1
TBK1 12 3
CDK2-Cyclin A 12 4
MLK3 11 5
SIK3 11 1
GCK 11 3
MARK1 10 0
JAK2 10 2
IRAK4 10 1
FGF-R1 9 2
ERK8 8 2
PDK1 8 0
MARK4 7 1
AMPK (hum) 5 1
MARK3 4 1
Aurora B 2 1
MLK1 2 0
VEGFR1 2 0
SIK2 2 1
NUAK1 1 0

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