Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
KU55933 C21H17NO3S2 395.49 ATM Li Y. (2010) Mol. Cancer Ther. 2010 Jan. 9(1) 113-25 Tocris Bioscience Download

Results as Barchart

View results as a bar chart
0.1µM
1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
DYRK1A 57 0
CK1 gamma 2 62 3
RIPK2 63 2
MST3 63 6
ERK8 63 2
MARK3 68 10
MST2 69 2
Aurora B 69 6
PIM3 73 0
GCK 74 15
MAP4K5 74 3
ULK1 74 10
MKK6 75 9
MST4 76 4
SIK3 76 4
MKK2 77 17
IKK epsilon 77 3
p38 gamma MAPK 77 8
MINK1 77 1
HIPK1 78 2
MLK1 78 10
PINK 78 4
LKB1 79 3
MLK3 79 13
TAO1 79 4
ERK5 79 13
RSK2 79 8
CK1 delta 79 1
TTBK2 80 13
IRAK4 80 1
TGFBR1 80 9
TBK1 81 0
BRK 81 3
TESK1 82 1
SmMLCK 82 8
CHK1 82 10
TAK1 83 3
VEGFR1 83 9
SIK2 83 2
p38 delta MAPK 83 1
MAP4K3 83 14
MNK1 83 4
IGF-1R 84 2
BTK 84 6
SRPK1 84 8
Src 85 0
FGF-R1 85 10
S6K1 85 2
PRK2 85 0
PKB alpha 86 1
TTBK1 86 2
MARK1 86 4
HIPK3 86 4
ROCK 2 86 3
JNK2 86 14
PIM1 86 5
EPH-B3 86 9
Lck 87 2
NEK6 87 4
PAK5 87 4
p38 beta MAPK 87 18
STK33 87 6
ERK2 88 1
TIE2 88 9
PKD1 88 2
CDK9-Cyclin T1 88 8
EPH-B2 88 2
PKB beta 89 3
MELK 89 12
TTK 89 3
PLK1 89 10
HIPK2 90 9
TrkA 90 9
TSSK1 90 8
EF2K 90 2
MKK1 90 7
CAMK1 91 3
IR 91 21
HER4 92 3
MARK2 92 9
p38 alpha MAPK 92 10
ZAP70 92 3
RSK1 92 1
CAMKK beta 93 6
YES1 93 3
PAK2 93 8
SYK 93 2
GSK3 beta 93 3
WNK1 93 9
PDK1 93 10
PRAK 94 2
CLK2 94 13
PKA 94 0
JNK1 94 14
MARK4 94 10
BRSK1 94 10
BRSK2 94 10
CDK2-Cyclin A 94 9
IRAK1 95 8
DDR2 95 3
Aurora A 95 7
MAPKAP-K2 95 2
MEKK1 95 9
SGK1 96 6
DYRK2 96 4
JAK2 96 6
PKC zeta 96 3
PAK6 97 8
PIM2 97 3
MAPKAP-K3 98 2
EPH-B4 98 9
MSK1 98 8
TLK1 98 5
ERK1 99 12
NUAK1 99 9
OSR1 99 2
ULK2 99 13
CK2 99 1
EIF2AK3 99 6
AMPK (hum) 100 7
ASK1 100 17
PAK4 100 24
ABL 101 6
NEK2a 101 16
CHK2 101 8
MPSK1 101 7
EPH-A4 101 12
IKK beta 102 8
PDGFRA 102 13
EPH-B1 102 1
MNK2 102 4
PHK 103 12
PKC alpha 103 11
PKC gamma 103 9
JNK3 104 5
IRR 107 5
DAPK1 107 22
EPH-A2 107 10
DYRK3 108 11
CSK 119 29
Screening Concentration: 0.1µM
Kinase % Activity Remainingsort descending Standard Deviation
MARK3 62 10
Aurora B 64 14
MST2 64 5
AMPK (hum) 65 8
MELK 67 2
p38 gamma MAPK 67 14
SIK2 67 3
MLK3 68 2
TAK1 68 4
MST3 68 8
ULK1 69 3
MARK1 69 3
MKK2 70 2
RIPK2 70 2
MINK1 71 4
MKK1 71 15
TSSK1 72 2
SIK3 72 5
MAP4K5 73 6
PKB alpha 73 2
IKK epsilon 73 6
RSK2 74 6
PRK2 74 6
CHK1 74 0
ERK8 75 2
TGFBR1 75 1
p38 beta MAPK 75 6
DYRK1A 76 6
MARK2 76 3
p38 delta MAPK 76 4
IR 77 12
MKK6 78 1
ERK2 78 2
VEGFR1 78 8
HIPK1 79 7
TAO1 79 9
IGF-1R 79 6
MST4 79 0
NEK6 80 8
IRAK4 80 1
CK1 delta 81 2
MLK1 81 11
PINK 81 6
MAP4K3 82 5
LKB1 82 9
CAMKK beta 82 6
HIPK3 82 4
S6K1 82 10
ROCK 2 82 5
JNK1 83 0
PAK5 83 2
JAK2 83 12
ULK2 84 5
HIPK2 84 11
SmMLCK 84 1
MARK4 84 3
CDK2-Cyclin A 84 7
EPH-B2 85 1
Src 85 15
TESK1 85 2
YES1 85 5
BRSK1 85 1
TIE2 85 16
GCK 85 16
Lck 86 4
PAK2 86 3
JNK2 86 0
TTK 86 4
PLK1 87 13
SRPK1 87 8
TTBK1 87 2
PKB beta 87 5
IRAK1 87 7
p38 alpha MAPK 87 2
WNK1 88 6
EPH-A4 88 12
RSK1 88 3
TLK1 88 1
ERK5 88 1
PAK6 88 6
CDK9-Cyclin T1 88 2
DYRK2 89 1
PKC alpha 89 11
SYK 89 1
DDR2 89 3
OSR1 89 5
MEKK1 90 13
CAMK1 90 4
BTK 90 2
MPSK1 90 2
MAPKAP-K2 91 2
EPH-B3 91 5
MAPKAP-K3 91 6
FGF-R1 91 14
BRK 91 3
TBK1 92 13
CK1 gamma 2 93 6
PDK1 93 8
CLK2 93 1
PKA 93 2
PIM1 93 3
MNK2 94 2
PRAK 94 6
TTBK2 94 9
ERK1 94 3
SGK1 94 2
TrkA 94 2
GSK3 beta 94 4
PKC gamma 95 4
ZAP70 95 5
PKD1 95 4
STK33 95 5
CK2 96 1
HER4 96 6
MSK1 97 8
EF2K 97 13
EPH-B4 97 17
CHK2 97 0
EPH-B1 98 4
EIF2AK3 98 1
IRR 98 7
DAPK1 98 2
PKC zeta 98 1
MNK1 99 4
Aurora A 99 10
NUAK1 99 10
DYRK3 100 2
NEK2a 100 1
ABL 101 5
IKK beta 102 4
PIM3 103 9
BRSK2 104 4
EPH-A2 104 12
PDGFRA 106 31
ASK1 108 17
JNK3 108 25
PIM2 108 14
PHK 110 21
CSK 112 17
PAK4 119 17

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