Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
STOCK2S-26016 C20H19N3O2 333.38976 WNK Mori T. (2013) Biochem J. 1 455(3) 339-45 InterBioScreen Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 89 9
MKK2 88 26
MKK6 98 3
ERK1 75 3
ERK2 95 2
ERK5 85 13
JNK1 94 1
JNK2 83 3
JNK3 101 1
p38 alpha MAPK 89 18
p38 beta MAPK 106 6
p38 gamma MAPK 95 1
p38 delta MAPK 96 1
ERK8 70 3
RSK1 84 10
RSK2 69 15
PDK1 106 11
PKB alpha 97 4
PKB beta 77 3
SGK1 94 7
S6K1 88 1
PKA 102 4
ROCK 2 76 4
PRK2 92 9
PKC alpha 90 3
PKC gamma 77 11
PKC zeta 108 2
PKD1 58 11
STK33 92 1
MSK1 102 14
MNK1 92 12
MNK2 97 17
MAPKAP-K2 99 10
MAPKAP-K3 88 8
PRAK 97 4
CAMKK beta 103 0
CAMK1 92 14
SmMLCK 99 0
PHK 86 1
DAPK1 93 8
CHK1 92 3
CHK2 81 11
GSK3 beta 107 5
CDK2-Cyclin A 87 5
CDK9-Cyclin T1 97 18
PLK1 102 0
Aurora A 105 4
Aurora B 67 8
TLK1 94 0
LKB1 88 3
AMPK (hum) 94 1
MARK1 84 4
MARK2 99 7
MARK3 112 12
MARK4 88 27
BRSK1 95 14
BRSK2 70 4
MELK 52 8
NUAK1 78 2
SIK2 92 13
SIK3 90 1
TSSK1 79 3
CK1 gamma 2 67 2
CK1 delta 27 2
CK2 108 15
TTBK1 95 6
TTBK2 100 10
DYRK1A 100 12
DYRK2 81 10
DYRK3 99 7
NEK2a 100 3
NEK6 100 6
IKK beta 90 14
IKK epsilon 85 2
TBK1 108 9
PIM1 85 2
PIM2 88 7
PIM3 72 8
SRPK1 89 3
EF2K 98 0
EIF2AK3 107 8
HIPK1 100 14
HIPK2 106 22
HIPK3 88 4
CLK2 83 2
PAK2 101 12
PAK4 94 2
PAK5 94 5
PAK6 94 2
MST2 81 20
MST3 105 5
MST4 92 11
GCK 88 10
MAP4K3 91 1
MAP4K5 77 1
MINK1 78 15
MEKK1 89 10
MLK1 96 0
MLK3 85 3
TESK1 98 4
TAO1 92 2
ASK1 107 14
TAK1 83 2
IRAK1 64 5
IRAK4 86 7
RIPK2 85 2
OSR1 118 8
TTK 83 3
MPSK1 88 9
WNK1 111 2
ULK1 102 11
ULK2 101 14
TGFBR1 101 5
Src 112 1
Lck 85 10
CSK 90 4
YES1 103 22
ABL 95 1
BTK 87 2
JAK2 88 6
SYK 78 5
ZAP70 127 12
TIE2 90 7
BRK 106 3
EPH-A2 95 11
EPH-A4 105 19
EPH-B1 118 14
EPH-B2 92 13
EPH-B3 94 8
EPH-B4 118 10
FGF-R1 74 6
HER4 110 9
IGF-1R 103 3
IR 66 9
IRR 87 10
TrkA 96 22
DDR2 110 8
VEGFR1 41 8
PDGFRA 86 7
PINK 98 4
Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 96 4
MKK2 81 5
MKK6 102 10
ERK1 101 3
ERK2 92 9
ERK5 83 6
JNK1 106 15
JNK2 93 6
JNK3 96 3
p38 alpha MAPK 85 8
p38 beta MAPK 113 10
p38 gamma MAPK 100 8
p38 delta MAPK 103 10
ERK8 90 9
RSK1 83 3
RSK2 125 0
PDK1 100 1
PKB alpha 94 6
PKB beta 93 14
SGK1 85 23
S6K1 88 17
PKA 93 5
ROCK 2 93 5
PRK2 99 2
PKC alpha 88 0
PKC gamma 100 19
PKC zeta 98 4
PKD1 82 7
STK33 106 18
MSK1 97 14
MNK1 99 8
MNK2 112 27
MAPKAP-K2 102 5
MAPKAP-K3 96 3
PRAK 107 11
CAMKK beta 95 3
CAMK1 96 2
SmMLCK 101 8
PHK 92 5
DAPK1 102 1
CHK1 90 6
CHK2 90 3
GSK3 beta 107 3
CDK2-Cyclin A 80 7
CDK9-Cyclin T1 83 1
PLK1 92 5
Aurora A 100 1
Aurora B 83 0
TLK1 123 31
LKB1 116 8
AMPK (hum) 88 17
MARK1 83 3
MARK2 92 5
MARK3 99 4
MARK4 118 51
BRSK1 84 8
BRSK2 101 18
MELK 72 10
NUAK1 85 4
SIK2 127 31
SIK3 87 2
TSSK1 61 11
CK1 gamma 2 95 11
CK1 delta 63 12
CK2 120 9
TTBK1 103 1
TTBK2 97 5
DYRK1A 108 22
DYRK2 100 7
DYRK3 101 1
NEK2a 102 6
NEK6 100 9
IKK beta 103 14
IKK epsilon 88 16
TBK1 99 3
PIM1 98 2
PIM2 99 4
PIM3 90 1
SRPK1 90 3
EF2K 107 8
EIF2AK3 108 9
HIPK1 100 18
HIPK2 102 10
HIPK3 95 8
CLK2 89 7
PAK2 104 7
PAK4 96 1
PAK5 95 11
PAK6 108 11
MST2 76 4
MST3 108 6
MST4 91 16
GCK 101 9
MAP4K3 74 11
MAP4K5 82 14
MINK1 86 9
MEKK1 99 20
MLK1 102 1
MLK3 98 5
TESK1 90 14
TAO1 98 7
ASK1 101 4
TAK1 101 16
IRAK1 94 7
IRAK4 92 21
RIPK2 97 10
OSR1 109 10
TTK 98 3
MPSK1 107 27
WNK1 115 5
ULK1 98 5
ULK2 102 4
TGFBR1 101 2
Src 87 0
Lck 107 3
CSK 100 4
YES1 92 5
ABL 88 4
BTK 90 11
JAK2 92 2
SYK 95 16
ZAP70 100 12
TIE2 90 4
BRK 101 3
EPH-A2 104 6
EPH-A4 119 37
EPH-B1 109 2
EPH-B2 109 13
EPH-B3 107 10
EPH-B4 94 4
FGF-R1 93 3
HER4 108 7
IGF-1R 94 8
IR 87 0
IRR 103 14
TrkA 103 17
DDR2 101 6
VEGFR1 63 7
PDGFRA 102 9
PINK 103 0

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