Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Tenovin-6 C25H34N4O2S 454.6 Cayman Download

Results as Barchart

View results as a bar chart
10µM
1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 97 2
MKK2 112 24
MKK6 98 1
ERK1 96 5
ERK2 103 6
ERK5 113 2
JNK1 103 5
JNK2 119 9
JNK3 112 3
p38 alpha MAPK 92 6
p38 beta MAPK 93 18
p38 gamma MAPK 110 5
p38 delta MAPK 112 16
ERK8 113 3
RSK1 105 6
RSK2 106 10
PDK1 118 17
PKB alpha 112 5
PKB beta 101 5
SGK1 81 9
S6K1 91 3
PKA 106 11
ROCK 2 96 10
PRK2 111 18
PKC alpha 119 21
PKC gamma 123 1
PKC zeta 102 6
PKD1 99 1
STK33 103 3
MSK1 92 3
MNK1 106 11
MNK2 115 8
MAPKAP-K2 93 2
MAPKAP-K3 91 7
PRAK 106 4
CAMKK beta 96 1
CAMK1 91 4
SmMLCK 112 7
PHK 99 2
DAPK1 102 9
CHK1 92 6
CHK2 102 0
GSK3 beta 108 0
CDK2-Cyclin A 95 9
CDK9-Cyclin T1 107 19
PLK1 110 4
Aurora A 98 2
Aurora B 89 5
TLK1 104 8
LKB1 86 5
AMPK (hum) 109 2
MARK1 100 9
MARK2 105 9
MARK3 97 3
MARK4 103 6
BRSK1 105 10
BRSK2 114 8
MELK 105 10
NUAK1 103 7
SIK2 93 2
SIK3 102 1
TSSK1 100 2
CK1 gamma 2 95 2
CK1 delta 101 8
CK2 103 8
TTBK1 103 4
TTBK2 110 19
DYRK1A 98 5
DYRK2 102 19
DYRK3 93 5
NEK2a 101 2
NEK6 99 1
IKK beta 96 3
IKK epsilon 106 4
TBK1 99 1
PIM1 98 9
PIM2 104 8
PIM3 102 2
SRPK1 94 2
EF2K 115 2
EIF2AK3 108 4
HIPK1 115 1
HIPK2 97 5
HIPK3 110 2
CLK2 98 6
PAK2 76 17
PAK4 90 1
PAK5 94 1
PAK6 86 4
MST2 94 5
MST3 97 4
MST4 106 11
GCK 93 3
MAP4K3 93 10
MAP4K5 89 2
MINK1 94 20
MEKK1 100 10
MLK1 103 6
MLK3 107 2
TESK1 87 3
TAO1 109 5
ASK1 103 10
TAK1 93 0
IRAK1 102 0
IRAK4 102 6
RIPK2 104 8
OSR1 104 3
TTK 95 2
MPSK1 121 0
WNK1 118 11
ULK1 88 4
ULK2 110 2
TGFBR1 101 7
Src 86 3
Lck 88 2
CSK 87 2
YES1 96 4
ABL 101 15
BTK 111 4
JAK2 101 4
SYK 84 8
ZAP70 108 1
TIE2 93 5
BRK 103 3
EPH-A2 98 8
EPH-A4 108 17
EPH-B1 87 4
EPH-B2 104 4
EPH-B3 103 11
EPH-B4 105 10
FGF-R1 96 2
HER4 118 6
IGF-1R 87 9
IR 100 13
IRR 110 4
TrkA 97 7
DDR2 113 4
VEGFR1 117 19
PDGFRA 37 2
PINK 93 15
Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 103 26
MKK2 103 2
MKK6 99 9
ERK1 105 13
ERK2 93 8
ERK5 94 7
JNK1 94 1
JNK2 118 4
JNK3 105 1
p38 alpha MAPK 93 0
p38 beta MAPK 87 1
p38 gamma MAPK 95 1
p38 delta MAPK 100 20
ERK8 89 7
RSK1 86 5
RSK2 111 5
PDK1 188 5
PKB alpha 115 8
PKB beta 86 1
SGK1 88 12
S6K1 86 0
PKA 106 3
ROCK 2 87 12
PRK2 100 3
PKC alpha 91 6
PKC gamma 104 0
PKC zeta 84 6
PKD1 107 2
STK33 95 5
MSK1 97 13
MNK1 109 5
MNK2 98 1
MAPKAP-K2 97 0
MAPKAP-K3 69 52
PRAK 102 4
CAMKK beta 67 2
CAMK1 62 4
SmMLCK 70 6
PHK 89 7
DAPK1 98 5
CHK1 86 5
CHK2 89 0
GSK3 beta 104 4
CDK2-Cyclin A 84 3
CDK9-Cyclin T1 102 12
PLK1 115 2
Aurora A 103 1
Aurora B 88 6
TLK1 99 5
LKB1 107 3
AMPK (hum) 122 5
MARK1 103 2
MARK2 92 9
MARK3 105 3
MARK4 97 4
BRSK1 110 2
BRSK2 131 2
MELK 112 29
NUAK1 101 1
SIK2 94 1
SIK3 109 6
TSSK1 95 4
CK1 gamma 2 87 11
CK1 delta 81 5
CK2 104 1
TTBK1 113 10
TTBK2 100 6
DYRK1A 95 10
DYRK2 104 5
DYRK3 92 11
NEK2a 83 4
NEK6 98 1
IKK beta 95 11
IKK epsilon 95 3
TBK1 111 5
PIM1 100 5
PIM2 100 0
PIM3 97 1
SRPK1 95 3
EF2K 125 11
EIF2AK3 99 1
HIPK1 99 1
HIPK2 88 6
HIPK3 97 4
CLK2 48 5
PAK2 89 13
PAK4 72 12
PAK5 75 2
PAK6 81 2
MST2 90 1
MST3 90 7
MST4 83 1
GCK 53 2
MAP4K3 91 6
MAP4K5 51 1
MINK1 71 7
MEKK1 112 15
MLK1 101 10
MLK3 103 9
TESK1 89 5
TAO1 108 2
ASK1 88 4
TAK1 81 14
IRAK1 103 5
IRAK4 86 3
RIPK2 94 1
OSR1 104 7
TTK 96 5
MPSK1 97 6
WNK1 109 5
ULK1 90 5
ULK2 94 10
TGFBR1 96 6
Src 105 15
Lck 67 8
CSK 83 8
YES1 113 19
ABL 103 3
BTK 97 2
JAK2 100 1
SYK 86 2
ZAP70 95 3
TIE2 97 12
BRK 111 2
EPH-A2 116 6
EPH-A4 126 3
EPH-B1 102 14
EPH-B2 109 7
EPH-B3 120 18
EPH-B4 119 6
FGF-R1 109 12
HER4 120 0
IGF-1R 76 11
IR 84 5
IRR 107 1
TrkA 112 1
DDR2 106 5
VEGFR1 92 0
PDGFRA 10 1
PINK 87 1

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