InhibitorScreening ConcentrationKinase% Activity RemainingStandard Deviation
Fostamatinib0.10µMMKK18924
Fostamatinib0.10µMMKK21151
Fostamatinib0.10µMMKK61051
Fostamatinib0.10µMERK110832
Fostamatinib0.10µMERK21257
Fostamatinib0.10µMERK5988
Fostamatinib0.10µMJNK110310
Fostamatinib0.10µMJNK2925
Fostamatinib0.10µMJNK31126
Fostamatinib0.10µMp38 alpha MAPK897
Fostamatinib0.10µMp38 beta MAPK11217
Fostamatinib0.10µMp38 gamma MAPK1291
Fostamatinib0.10µMp38 delta MAPK1029
Fostamatinib0.10µMERK81072
Fostamatinib0.10µMRSK19614
Fostamatinib0.10µMRSK210011
Fostamatinib0.10µMPDK110612
Fostamatinib0.10µMPKB alpha 10913
Fostamatinib0.10µMPKB beta 1163
Fostamatinib0.10µMSGK1987
Fostamatinib0.10µMS6K11159
Fostamatinib0.10µMPKA10517
Fostamatinib0.10µMROCK 2992
Fostamatinib0.10µMPRK210017
Fostamatinib0.10µMPKC alpha 1019
Fostamatinib0.10µMPKC gamma 1100
Fostamatinib0.10µMPKC zeta 1227
Fostamatinib0.10µMPKD11105
Fostamatinib0.10µMSTK331168
Fostamatinib0.10µMMSK1964
Fostamatinib0.10µMMNK11077
Fostamatinib0.10µMMNK21033
Fostamatinib0.10µMMAPKAP-K2 1163
Fostamatinib0.10µMMAPKAP-K3987
Fostamatinib0.10µMPRAK927
Fostamatinib0.10µMCAMKK beta 11713
Fostamatinib0.10µMCAMK1971
Fostamatinib0.10µMSmMLCK10415
Fostamatinib0.10µMPHK1135
Fostamatinib0.10µMDAPK11144
Fostamatinib0.10µMCHK111211
Fostamatinib0.10µMCHK21051
Fostamatinib0.10µMGSK3 beta 9212
Fostamatinib0.10µMCDK2-Cyclin A1085
Fostamatinib0.10µMCDK9-Cyclin T110416
Fostamatinib0.10µMPLK1962
Fostamatinib0.10µMAurora A7542
Fostamatinib0.10µMAurora B603
Fostamatinib0.10µMTLK1843
Fostamatinib0.10µMLKB11196
Fostamatinib0.10µMAMPK (hum)1123
Fostamatinib0.10µMMARK19313
Fostamatinib0.10µMMARK2972
Fostamatinib0.10µMMARK3952
Fostamatinib0.10µMMARK4965
Fostamatinib0.10µMBRSK11030
Fostamatinib0.10µMBRSK2982
Fostamatinib0.10µMMELK1006
Fostamatinib0.10µMNUAK1720
Fostamatinib0.10µMSIK210621
Fostamatinib0.10µMSIK3999
Fostamatinib0.10µMTSSK1833
Fostamatinib0.10µMCK1 gamma 210713
Fostamatinib0.10µMCK1 delta 976
Fostamatinib0.10µMCK210119
Fostamatinib0.10µMTTBK110310
Fostamatinib0.10µMTTBK21225
Fostamatinib0.10µMDYRK1A9323
Fostamatinib0.10µMDYRK21011
Fostamatinib0.10µMDYRK3863
Fostamatinib0.10µMNEK2a1024
Fostamatinib0.10µMNEK61018
Fostamatinib0.10µMIKK beta 1174
Fostamatinib0.10µMIKK epsilon 911
Fostamatinib0.10µMTBK1891
Fostamatinib0.10µMPIM11294
Fostamatinib0.10µMPIM21062
Fostamatinib0.10µMPIM3638
Fostamatinib0.10µMSRPK11024
Fostamatinib0.10µMEF2K1095
Fostamatinib0.10µMEIF2AK31057
Fostamatinib0.10µMHIPK111912
Fostamatinib0.10µMHIPK210510
Fostamatinib0.10µMHIPK311913
Fostamatinib0.10µMCLK21126
Fostamatinib0.10µMPAK2943
Fostamatinib0.10µMPAK4728
Fostamatinib0.10µMPAK5906
Fostamatinib0.10µMPAK612314
Fostamatinib0.10µMMST21146
Fostamatinib0.10µMMST31148
Fostamatinib0.10µMMST41055
Fostamatinib0.10µMGCK10615
Fostamatinib0.10µMMAP4K31035
Fostamatinib0.10µMMAP4K51268
Fostamatinib0.10µMMINK11163
Fostamatinib0.10µMMEKK1963
Fostamatinib0.10µMMLK1502
Fostamatinib0.10µMMLK3581
Fostamatinib0.10µMTESK1961
Fostamatinib0.10µMTAO11013
Fostamatinib0.10µMASK1993
Fostamatinib0.10µMTAK112024
Fostamatinib0.10µMIRAK11023
Fostamatinib0.10µMIRAK41053
Fostamatinib0.10µMRIPK210710
Fostamatinib0.10µMOSR1942
Fostamatinib0.10µMTTK1061
Fostamatinib0.10µMMPSK113735
Fostamatinib0.10µMWNK1996
Fostamatinib0.10µMULK11209
Fostamatinib0.10µMULK2999
Fostamatinib0.10µMTGFBR11065
Fostamatinib0.10µMSrc802
Fostamatinib0.10µMLck1072
Fostamatinib0.10µMCSK9912
Fostamatinib0.10µMYES1874
Fostamatinib0.10µMABL1133
Fostamatinib0.10µMBTK673
Fostamatinib0.10µMJAK2506
Fostamatinib0.10µMSYK790
Fostamatinib0.10µMZAP70973
Fostamatinib0.10µMTIE2942
Fostamatinib0.10µMBRK987
Fostamatinib0.10µMEPH-A2623
Fostamatinib0.10µMEPH-A4492
Fostamatinib0.10µMEPH-B1481
Fostamatinib0.10µMEPH-B2904
Fostamatinib0.10µMEPH-B31080
Fostamatinib0.10µMEPH-B4789
Fostamatinib0.10µMFGF-R11152
Fostamatinib0.10µMHER4983
Fostamatinib0.10µMIGF-1R13719
Fostamatinib0.10µMIR1169
Fostamatinib0.10µMIRR11218
Fostamatinib0.10µMTrkA620
Fostamatinib0.10µMDDR29112
Fostamatinib0.10µMVEGFR17414
Fostamatinib0.10µMPDGFRA1151
Fostamatinib0.10µMPINK1084
Fostamatinib1.00µMMKK11130
Fostamatinib1.00µMMKK2985
Fostamatinib1.00µMMKK61051
Fostamatinib1.00µMERK11000
Fostamatinib1.00µMERK21011
Fostamatinib1.00µMERK59613
Fostamatinib1.00µMJNK1978
Fostamatinib1.00µMJNK2857
Fostamatinib1.00µMJNK3771
Fostamatinib1.00µMp38 alpha MAPK10411
Fostamatinib1.00µMp38 beta MAPK9614
Fostamatinib1.00µMp38 gamma MAPK1347
Fostamatinib1.00µMp38 delta MAPK1026
Fostamatinib1.00µMERK8866
Fostamatinib1.00µMRSK19424
Fostamatinib1.00µMRSK28716
Fostamatinib1.00µMPDK18915
Fostamatinib1.00µMPKB alpha 10711
Fostamatinib1.00µMPKB beta 1180
Fostamatinib1.00µMSGK1855
Fostamatinib1.00µMS6K1737
Fostamatinib1.00µMPKA1117
Fostamatinib1.00µMROCK 2965
Fostamatinib1.00µMPRK21006
Fostamatinib1.00µMPKC alpha 1060
Fostamatinib1.00µMPKC gamma 1022
Fostamatinib1.00µMPKC zeta 1151
Fostamatinib1.00µMPKD1957
Fostamatinib1.00µMSTK33974
Fostamatinib1.00µMMSK1892
Fostamatinib1.00µMMNK110421
Fostamatinib1.00µMMNK21006
Fostamatinib1.00µMMAPKAP-K2 1075
Fostamatinib1.00µMMAPKAP-K3988
Fostamatinib1.00µMPRAK10511
Fostamatinib1.00µMCAMKK beta 10215
Fostamatinib1.00µMCAMK1989
Fostamatinib1.00µMSmMLCK10511
Fostamatinib1.00µMPHK991
Fostamatinib1.00µMDAPK11017
Fostamatinib1.00µMCHK11050
Fostamatinib1.00µMCHK2981
Fostamatinib1.00µMGSK3 beta 9412
Fostamatinib1.00µMCDK2-Cyclin A1109
Fostamatinib1.00µMCDK9-Cyclin T111110
Fostamatinib1.00µMPLK1996
Fostamatinib1.00µMAurora A2932
Fostamatinib1.00µMAurora B232
Fostamatinib1.00µMTLK18912
Fostamatinib1.00µMLKB11156
Fostamatinib1.00µMAMPK (hum)873
Fostamatinib1.00µMMARK11088
Fostamatinib1.00µMMARK2947
Fostamatinib1.00µMMARK31038
Fostamatinib1.00µMMARK4956
Fostamatinib1.00µMBRSK11121
Fostamatinib1.00µMBRSK2951
Fostamatinib1.00µMMELK982
Fostamatinib1.00µMNUAK1701
Fostamatinib1.00µMSIK29612
Fostamatinib1.00µMSIK3869
Fostamatinib1.00µMTSSK19314
Fostamatinib1.00µMCK1 gamma 21093
Fostamatinib1.00µMCK1 delta 1098
Fostamatinib1.00µMCK210518
Fostamatinib1.00µMTTBK11137
Fostamatinib1.00µMTTBK21212
Fostamatinib1.00µMDYRK1A950
Fostamatinib1.00µMDYRK21015
Fostamatinib1.00µMDYRK3922
Fostamatinib1.00µMNEK2a1051
Fostamatinib1.00µMNEK61084
Fostamatinib1.00µMIKK beta 1099
Fostamatinib1.00µMIKK epsilon 721
Fostamatinib1.00µMTBK18214
Fostamatinib1.00µMPIM11031
Fostamatinib1.00µMPIM21032
Fostamatinib1.00µMPIM310410
Fostamatinib1.00µMSRPK11043
Fostamatinib1.00µMEF2K10510
Fostamatinib1.00µMEIF2AK3970
Fostamatinib1.00µMHIPK11098
Fostamatinib1.00µMHIPK21093
Fostamatinib1.00µMHIPK31130
Fostamatinib1.00µMCLK29811
Fostamatinib1.00µMPAK2994
Fostamatinib1.00µMPAK4372
Fostamatinib1.00µMPAK5755
Fostamatinib1.00µMPAK611119
Fostamatinib1.00µMMST214538
Fostamatinib1.00µMMST31038
Fostamatinib1.00µMMST4932
Fostamatinib1.00µMGCK950
Fostamatinib1.00µMMAP4K31093
Fostamatinib1.00µMMAP4K51130
Fostamatinib1.00µMMINK1957
Fostamatinib1.00µMMEKK11091
Fostamatinib1.00µMMLK160
Fostamatinib1.00µMMLK3213
Fostamatinib1.00µMTESK1997
Fostamatinib1.00µMTAO1988
Fostamatinib1.00µMASK11231
Fostamatinib1.00µMTAK110323
Fostamatinib1.00µMIRAK1885
Fostamatinib1.00µMIRAK4920
Fostamatinib1.00µMRIPK2958
Fostamatinib1.00µMOSR11027
Fostamatinib1.00µMTTK9610
Fostamatinib1.00µMMPSK11086
Fostamatinib1.00µMWNK11038
Fostamatinib1.00µMULK1688
Fostamatinib1.00µMULK28810
Fostamatinib1.00µMTGFBR11126
Fostamatinib1.00µMSrc415
Fostamatinib1.00µMLck611
Fostamatinib1.00µMCSK8619
Fostamatinib1.00µMYES1642
Fostamatinib1.00µMABL1124
Fostamatinib1.00µMBTK291
Fostamatinib1.00µMJAK238
Fostamatinib1.00µMSYK739
Fostamatinib1.00µMZAP70510
Fostamatinib1.00µMTIE21004
Fostamatinib1.00µMBRK957
Fostamatinib1.00µMEPH-A2342
Fostamatinib1.00µMEPH-A4100
Fostamatinib1.00µMEPH-B1102
Fostamatinib1.00µMEPH-B2537
Fostamatinib1.00µMEPH-B3765
Fostamatinib1.00µMEPH-B4223
Fostamatinib1.00µMFGF-R1758
Fostamatinib1.00µMHER4651
Fostamatinib1.00µMIGF-1R254
Fostamatinib1.00µMIR988
Fostamatinib1.00µMIRR5920
Fostamatinib1.00µMTrkA351
Fostamatinib1.00µMDDR2661
Fostamatinib1.00µMVEGFR1315
Fostamatinib1.00µMPDGFRA9413
Fostamatinib1.00µMPINK1083
Fostamatinib10.00µMMKK110556
Fostamatinib10.00µMMKK29711
Fostamatinib10.00µMMKK6834
Fostamatinib10.00µMERK1941
Fostamatinib10.00µMERK21001
Fostamatinib10.00µMERK5846
Fostamatinib10.00µMJNK17044
Fostamatinib10.00µMJNK2261
Fostamatinib10.00µMJNK3242
Fostamatinib10.00µMp38 alpha MAPK1046
Fostamatinib10.00µMp38 beta MAPK9624
Fostamatinib10.00µMp38 gamma MAPK11024
Fostamatinib10.00µMp38 delta MAPK716
Fostamatinib10.00µMERK8360
Fostamatinib10.00µMRSK16217
Fostamatinib10.00µMRSK27835
Fostamatinib10.00µMPDK17455
Fostamatinib10.00µMPKB alpha 9811
Fostamatinib10.00µMPKB beta 993
Fostamatinib10.00µMSGK1303
Fostamatinib10.00µMS6K1271
Fostamatinib10.00µMPKA610
Fostamatinib10.00µMROCK 2864
Fostamatinib10.00µMPRK2698
Fostamatinib10.00µMPKC alpha 782
Fostamatinib10.00µMPKC gamma 865
Fostamatinib10.00µMPKC zeta 1138
Fostamatinib10.00µMPKD1989
Fostamatinib10.00µMSTK337355
Fostamatinib10.00µMMSK1717
Fostamatinib10.00µMMNK18810
Fostamatinib10.00µMMNK2714
Fostamatinib10.00µMMAPKAP-K2 1081
Fostamatinib10.00µMMAPKAP-K31002
Fostamatinib10.00µMPRAK1004
Fostamatinib10.00µMCAMKK beta 6620
Fostamatinib10.00µMCAMK19013
Fostamatinib10.00µMSmMLCK928
Fostamatinib10.00µMPHK866
Fostamatinib10.00µMDAPK19944
Fostamatinib10.00µMCHK1813
Fostamatinib10.00µMCHK27433
Fostamatinib10.00µMGSK3 beta 760
Fostamatinib10.00µMCDK2-Cyclin A841
Fostamatinib10.00µMCDK9-Cyclin T1977
Fostamatinib10.00µMPLK1554
Fostamatinib10.00µMAurora A4562
Fostamatinib10.00µMAurora B4655
Fostamatinib10.00µMTLK11036
Fostamatinib10.00µMLKB1372
Fostamatinib10.00µMAMPK (hum)280
Fostamatinib10.00µMMARK1992
Fostamatinib10.00µMMARK29711
Fostamatinib10.00µMMARK38743
Fostamatinib10.00µMMARK4769
Fostamatinib10.00µMBRSK19625
Fostamatinib10.00µMBRSK2911
Fostamatinib10.00µMMELK8514
Fostamatinib10.00µMNUAK1190
Fostamatinib10.00µMSIK2377
Fostamatinib10.00µMSIK3729
Fostamatinib10.00µMTSSK1430
Fostamatinib10.00µMCK1 gamma 2984
Fostamatinib10.00µMCK1 delta 9414
Fostamatinib10.00µMCK2625
Fostamatinib10.00µMTTBK11081
Fostamatinib10.00µMTTBK21162
Fostamatinib10.00µMDYRK1A802
Fostamatinib10.00µMDYRK2747
Fostamatinib10.00µMDYRK38710
Fostamatinib10.00µMNEK2a581
Fostamatinib10.00µMNEK68820
Fostamatinib10.00µMIKK beta 7710
Fostamatinib10.00µMIKK epsilon 192
Fostamatinib10.00µMTBK110012
Fostamatinib10.00µMPIM11129
Fostamatinib10.00µMPIM2882
Fostamatinib10.00µMPIM3843
Fostamatinib10.00µMSRPK11063
Fostamatinib10.00µMEF2K942
Fostamatinib10.00µMEIF2AK3554
Fostamatinib10.00µMHIPK19332
Fostamatinib10.00µMHIPK2972
Fostamatinib10.00µMHIPK310315
Fostamatinib10.00µMCLK2390
Fostamatinib10.00µMPAK2596
Fostamatinib10.00µMPAK460
Fostamatinib10.00µMPAK5278
Fostamatinib10.00µMPAK6646
Fostamatinib10.00µMMST26415
Fostamatinib10.00µMMST311519
Fostamatinib10.00µMMST4798
Fostamatinib10.00µMGCK8654
Fostamatinib10.00µMMAP4K3600
Fostamatinib10.00µMMAP4K5754
Fostamatinib10.00µMMINK1908
Fostamatinib10.00µMMEKK112237
Fostamatinib10.00µMMLK140
Fostamatinib10.00µMMLK340
Fostamatinib10.00µMTESK1466
Fostamatinib10.00µMTAO1748
Fostamatinib10.00µMASK11082
Fostamatinib10.00µMTAK16313
Fostamatinib10.00µMIRAK1243
Fostamatinib10.00µMIRAK4624
Fostamatinib10.00µMRIPK2824
Fostamatinib10.00µMOSR1996
Fostamatinib10.00µMTTK744
Fostamatinib10.00µMMPSK1668
Fostamatinib10.00µMWNK11036
Fostamatinib10.00µMULK1160
Fostamatinib10.00µMULK2302
Fostamatinib10.00µMTGFBR11078
Fostamatinib10.00µMSrc867
Fostamatinib10.00µMLck82
Fostamatinib10.00µMCSK162
Fostamatinib10.00µMYES1170
Fostamatinib10.00µMABL9112
Fostamatinib10.00µMBTK150
Fostamatinib10.00µMJAK2-512
Fostamatinib10.00µMSYK5449
Fostamatinib10.00µMZAP7071
Fostamatinib10.00µMTIE2684
Fostamatinib10.00µMBRK1176
Fostamatinib10.00µMEPH-A292
Fostamatinib10.00µMEPH-A41041
Fostamatinib10.00µMEPH-B130
Fostamatinib10.00µMEPH-B261
Fostamatinib10.00µMEPH-B3316
Fostamatinib10.00µMEPH-B44858
Fostamatinib10.00µMFGF-R1221
Fostamatinib10.00µMHER4253
Fostamatinib10.00µMIGF-1R71
Fostamatinib10.00µMIR110
Fostamatinib10.00µMIRR180
Fostamatinib10.00µMTrkA1352
Fostamatinib10.00µMDDR2145
Fostamatinib10.00µMVEGFR111830
Fostamatinib10.00µMPDGFRA7366
Fostamatinib10.00µMPINK9222