Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
CAY10576 C22H19N3O5S2 469.5 IKKe Cayman Download

Results as Barchart

View results as a bar chart
10µM
1µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
ROCK 2 61 5
MAP4K5 67 3
MLK1 67 2
MST3 70 11
BRK 72 4
ULK1 72 2
MAPKAP-K3 75 7
EPH-B3 75 24
HIPK1 76 8
MST2 77 0
DYRK3 78 2
MST4 79 6
ERK2 79 9
CHK2 79 3
PINK 80 3
HIPK3 80 1
MAP4K3 82 7
TAO1 82 5
IGF-1R 82 9
TIE2 83 2
ERK8 85 2
RSK1 87 6
RSK2 87 9
CDK2-Cyclin A 88 9
EPH-A4 88 9
MAPKAP-K2 88 15
ULK2 88 2
MKK6 88 3
S6K1 88 3
MARK4 88 8
IKK epsilon 88 6
VEGFR1 89 4
PDGFRA 90 1
GCK 90 5
PDK1 90 9
ERK1 90 2
TrkA 90 10
TTK 91 8
Aurora B 91 5
CK2 91 14
AMPK (hum) 91 15
FGF-R1 91 3
TESK1 91 12
YES1 91 3
PKC zeta 91 7
EPH-B1 92 1
MEKK1 92 4
JNK1 92 7
PRK2 92 4
p38 beta MAPK 92 5
MNK1 93 1
PIM3 93 1
MINK1 93 22
NEK2a 93 3
PKB alpha 94 2
MARK1 94 9
CHK1 94 15
MNK2 95 13
PKB beta 95 6
MARK2 95 2
TSSK1 96 4
MKK1 96 19
EF2K 96 4
DAPK1 96 3
PAK4 96 3
BTK 96 2
JNK3 96 3
PKC gamma 96 4
IRAK4 96 4
SIK2 97 9
AMPK 97 1
SYK 97 5
p38 delta MAPK 98 1
MSK1 98 4
EPH-A2 98 14
Aurora A 98 13
IRAK1 98 10
BRSK2 98 9
p38 gamma MAPK 99 7
CK1 gamma 2 99 8
MKK2 99 2
SGK1 99 7
CLK2 99 3
IRR 99 12
JAK2 99 7
CDK9-Cyclin T1 100 8
TLK1 100 8
CK1 delta 100 5
EPH-B4 100 2
TAK1 100 4
RIPK2 100 20
WNK1 102 3
SRPK1 102 11
SmMLCK 102 15
NEK6 102 10
EIF2AK3 103 1
DYRK1A 103 4
ERK5 103 10
PHK 103 7
JNK2 103 13
PKC alpha 103 3
MELK 103 0
ZAP70 103 15
NUAK1 104 11
PIM1 104 11
MPSK1 104 10
MARK3 104 2
IKK beta 104 7
DDR2 104 4
STK33 105 3
PRAK 105 7
CAMK1 105 1
CSK 105 5
HER4 105 7
PAK2 105 1
IR 105 24
PAK6 105 4
OSR1 106 4
SIK3 106 1
HIPK2 106 16
MLK3 106 7
GSK3 beta 106 15
CAMKK beta 107 8
DYRK2 108 13
PKD1 109 8
PIM2 109 7
PKA 109 12
TBK1 110 6
PAK5 111 9
p38 alpha MAPK 111 7
ASK1 112 10
PLK1 113 8
TTBK1 113 14
BRSK1 113 7
ABL 114 1
TTBK2 116 17
Lck 116 5
Src 117 5
TGFBR1 119 22
EPH-B2 123 9
LKB1 123 5
Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
MLK1 64 3
MAP4K5 70 15
HIPK1 71 3
ULK1 72 4
ROCK 2 73 3
MST3 73 11
VEGFR1 74 10
MST4 75 6
TIE2 76 10
HIPK3 79 14
TAO1 79 10
BRK 79 2
PINK 79 9
FGF-R1 80 1
MAP4K3 81 7
EPH-B3 81 3
MST2 81 11
MAPKAP-K3 84 2
ERK2 84 3
MINK1 85 1
S6K1 85 1
AMPK (hum) 87 4
YES1 87 1
MAPKAP-K2 88 6
TTBK2 89 4
PKA 89 1
IGF-1R 89 9
PDK1 90 13
TrkA 90 6
CHK2 90 2
CDK2-Cyclin A 90 7
ERK8 90 6
MNK2 91 5
MARK4 91 0
ERK1 92 0
TESK1 92 6
PAK4 92 16
PKC zeta 92 2
EF2K 94 3
AMPK 94 1
MELK 94 4
SIK3 94 8
WNK1 95 1
MKK1 95 3
ULK2 95 6
SGK1 95 9
SYK 95 1
PIM1 95 11
GCK 95 7
RSK1 96 5
RSK2 96 4
CLK2 96 8
MARK3 96 15
DAPK1 96 0
IRAK4 96 4
MSK1 96 0
MNK1 97 6
TLK1 97 2
CK1 delta 97 10
CAMKK beta 97 1
IRAK1 97 14
CSK 98 2
ERK5 98 2
DYRK3 98 13
ABL 98 5
PKC gamma 98 1
RIPK2 98 14
MPSK1 98 9
EPH-B1 99 6
EPH-B4 99 18
MARK2 99 2
BTK 99 18
p38 delta MAPK 99 3
STK33 99 5
Aurora B 100 6
MKK6 100 9
HER4 100 11
SmMLCK 100 4
JNK1 100 5
TAK1 100 2
PKC alpha 100 4
TTK 100 5
Lck 101 2
Aurora A 102 3
CK1 gamma 2 102 3
NEK2a 102 9
CHK1 102 12
GSK3 beta 102 4
p38 gamma MAPK 102 9
SRPK1 103 7
CK2 103 6
PKB beta 103 5
NEK6 103 1
DDR2 103 14
EPH-A4 104 1
MEKK1 104 4
MLK3 104 2
JNK3 104 1
PKB alpha 105 3
IKK beta 105 17
SIK2 105 10
PIM2 105 7
EIF2AK3 106 5
DYRK2 106 1
PAK6 106 1
PKD1 106 8
EPH-A2 106 11
CAMK1 107 3
JNK2 107 9
PRK2 107 1
IRR 107 5
PAK5 107 4
IKK epsilon 107 9
TBK1 107 5
OSR1 107 11
PDGFRA 107 0
CDK9-Cyclin T1 107 18
PLK1 107 4
TSSK1 108 9
PIM3 108 7
TGFBR1 108 3
HIPK2 108 15
ASK1 109 14
p38 alpha MAPK 109 5
NUAK1 109 15
DYRK1A 110 6
ZAP70 110 2
MKK2 111 4
MARK1 112 7
BRSK1 113 0
p38 beta MAPK 113 0
PHK 114 1
BRSK2 114 11
PRAK 115 21
IR 116 21
PAK2 117 2
JAK2 117 1
EPH-B2 119 17
TTBK1 123 7
Src 130 5
LKB1 138 17

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