Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Amlexanox C16H14N2O4 298.293 TBK1, IKKe Tocris Download

Results as Barchart

View results as a bar chart
10µM
1µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
MLK3 5 0
MLK1 6 2
CHK2 12 0
SmMLCK 13 1
PIM3 14 0
VEGFR1 15 0
SRPK1 16 1
TBK1 22 0
IKK epsilon 28 4
IGF-1R 31 0
IR 36 2
CK1 gamma 2 36 0
CAMKK beta 40 1
DAPK1 43 12
MAP4K5 46 0
TrkA 49 7
BTK 51 6
IRR 53 1
AMPK (hum) 55 5
RIPK2 56 2
MELK 64 14
CK2 65 3
CAMK1 66 10
BRK 66 4
PIM1 67 1
TTK 67 0
S6K1 69 2
DYRK1A 69 2
RSK1 70 1
EPH-A4 71 3
HER4 73 8
MNK1 73 11
MAPKAP-K3 74 10
JAK2 74 0
SGK1 79 1
DYRK2 79 17
SYK 79 10
STK33 79 5
ERK8 79 4
MAP4K3 79 6
CSK 81 7
PKB beta 82 8
HIPK1 82 1
IRAK1 83 2
PKC gamma 83 5
MAPKAP-K2 84 8
MST2 84 4
PDGFRA 84 12
SIK2 84 2
CK1 delta 85 4
Src 85 6
MARK4 85 6
PKC zeta 85 8
CDK2-Cyclin A 85 11
TIE2 85 2
TTBK2 86 8
TESK1 86 6
ROCK 2 86 13
ABL 86 12
TAK1 86 6
TSSK1 86 2
BRSK2 87 2
GCK 87 2
PRAK 88 1
EPH-B4 88 6
CLK2 88 12
MINK1 89 16
ULK2 89 7
MST4 89 11
DDR2 90 4
RSK2 90 2
PKB alpha 91 2
BRSK1 91 7
NUAK1 91 8
p38 delta MAPK 91 5
MNK2 91 4
MST3 92 11
PLK1 92 3
MKK2 93 0
HIPK2 93 23
HIPK3 93 4
DYRK3 93 7
p38 gamma MAPK 93 5
Aurora B 93 15
ULK1 93 8
MARK2 94 4
YES1 94 10
p38 beta MAPK 94 1
EPH-B3 95 13
MARK1 95 14
ERK5 95 1
PHK 95 1
FGF-R1 96 13
ERK2 96 4
IKK beta 96 8
GSK3 beta 96 10
NEK2a 97 10
IRAK4 97 16
CDK9-Cyclin T1 97 0
TGFBR1 98 10
PKA 98 6
JNK2 98 3
PAK4 98 3
JNK3 98 1
PKC alpha 98 4
EPH-A2 98 9
MPSK1 99 6
MARK3 100 12
SIK3 100 3
ERK1 101 22
MKK1 102 12
PDK1 102 16
EF2K 102 12
MEKK1 102 16
Lck 102 10
PAK5 102 7
PKD1 102 13
PINK 102 10
EPH-B1 102 1
MKK6 103 8
p38 alpha MAPK 103 9
OSR1 103 8
MSK1 103 3
JNK1 104 0
EPH-B2 105 3
WNK1 105 0
TTBK1 107 12
EIF2AK3 108 1
NEK6 108 0
TLK1 109 2
TAO1 109 6
PAK2 109 2
ZAP70 109 7
PAK6 110 3
Aurora A 110 8
PIM2 112 15
AMPK 113 16
PRK2 113 25
CHK1 113 1
ASK1 116 6
LKB1 122 30
Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
MLK3 10 0
MLK1 18 1
CHK2 47 4
VEGFR1 49 4
SmMLCK 53 7
PIM3 53 4
SRPK1 58 3
MAP4K5 65 8
BRK 66 7
IGF-1R 68 7
TBK1 73 9
MST3 73 6
DYRK1A 74 5
YES1 74 7
ROCK 2 74 7
EPH-B3 74 7
CK1 gamma 2 77 4
ULK1 77 6
MKK6 77 1
TIE2 78 2
S6K1 79 10
TESK1 79 8
DAPK1 79 6
HIPK1 79 0
TrkA 80 9
SYK 81 12
PAK4 82 13
MST4 82 6
TTK 82 2
Aurora B 83 9
JNK1 84 2
BTK 84 5
IKK epsilon 84 16
MAP4K3 84 0
MAPKAP-K3 84 8
CK2 84 14
IRR 85 1
MST2 85 1
MINK1 85 3
ERK2 86 10
MARK3 86 10
MARK1 87 12
SIK2 87 8
RSK1 87 5
PKB beta 87 0
PRAK 87 18
MARK2 88 0
AMPK (hum) 89 8
PKC gamma 89 11
MNK2 89 0
HIPK3 90 3
TAO1 90 0
CK1 delta 90 3
MKK2 90 3
CLK2 91 12
PKC alpha 91 10
MELK 91 7
PIM1 91 7
GCK 91 6
EPH-B1 91 5
CSK 92 12
NEK2a 92 8
CDK2-Cyclin A 92 8
ERK8 92 11
SGK1 93 8
PAK5 93 4
EIF2AK3 93 7
CAMKK beta 94 4
JNK3 94 1
RIPK2 94 3
STK33 94 11
MNK1 94 4
HER4 95 4
p38 delta MAPK 95 2
RSK2 95 7
TTBK1 95 3
DYRK3 96 1
JNK2 96 11
MARK4 96 11
PINK 96 2
TSSK1 96 5
PDK1 96 11
LKB1 96 8
PKA 97 2
SIK3 97 3
EPH-A4 97 8
MKK1 97 2
MAPKAP-K2 97 10
TTBK2 98 7
IR 98 4
IRAK1 98 2
IRAK4 98 4
ZAP70 98 4
PLK1 98 3
MPSK1 98 7
Aurora A 98 7
ULK2 98 11
PKB alpha 98 4
ERK5 99 2
p38 beta MAPK 99 5
MEKK1 100 8
DYRK2 101 16
EPH-B4 101 2
HIPK2 102 11
FGF-R1 102 13
BRSK2 102 5
PKC zeta 102 6
GSK3 beta 102 2
TAK1 103 13
NEK6 103 1
Src 103 3
IKK beta 104 12
p38 gamma MAPK 104 1
EPH-A2 104 16
EF2K 104 10
PAK2 105 8
PAK6 105 2
OSR1 105 8
PIM2 105 9
Lck 106 0
ABL 106 23
PRK2 106 3
PDGFRA 106 2
TLK1 106 4
CHK1 107 2
WNK1 107 6
CAMK1 108 25
PHK 108 4
CDK9-Cyclin T1 108 3
ERK1 109 15
BRSK1 110 3
TGFBR1 110 16
MSK1 111 2
AMPK 111 24
ASK1 112 21
DDR2 112 13
JAK2 113 0
PKD1 115 16
NUAK1 116 12
EPH-B2 118 19
p38 alpha MAPK 119 3

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