Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Amlexanox C16H14N2O4 298.293 TBK1, IKKe Tocris Download

Results as Barchart

View results as a bar chart
10µM
1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 97 2
MKK2 90 3
MKK6 77 1
ERK1 109 15
ERK2 86 10
ERK5 99 2
JNK1 84 2
JNK2 96 11
JNK3 94 1
p38 alpha MAPK 119 3
p38 beta MAPK 99 5
p38 gamma MAPK 104 1
p38 delta MAPK 95 2
ERK8 92 11
RSK1 87 5
RSK2 95 7
PDK1 96 11
PKB alpha 98 4
PKB beta 87 0
SGK1 93 8
S6K1 79 10
PKA 97 2
ROCK 2 74 7
PRK2 106 3
PKC alpha 91 10
PKC gamma 89 11
PKC zeta 102 6
PKD1 115 16
STK33 94 11
MSK1 111 2
MNK1 94 4
MNK2 89 0
MAPKAP-K2 97 10
MAPKAP-K3 84 8
PRAK 87 18
CAMKK beta 94 4
CAMK1 108 25
SmMLCK 53 7
PHK 108 4
DAPK1 79 6
CHK1 107 2
CHK2 47 4
GSK3 beta 102 2
CDK2-Cyclin A 92 8
CDK9-Cyclin T1 108 3
PLK1 98 3
Aurora A 98 7
Aurora B 83 9
TLK1 106 4
LKB1 96 8
AMPK 111 24
AMPK (hum) 89 8
MARK1 87 12
MARK2 88 0
MARK3 86 10
MARK4 96 11
BRSK1 110 3
BRSK2 102 5
MELK 91 7
NUAK1 116 12
SIK2 87 8
SIK3 97 3
TSSK1 96 5
CK1 gamma 2 77 4
CK1 delta 90 3
CK2 84 14
TTBK1 95 3
TTBK2 98 7
DYRK1A 74 5
DYRK2 101 16
DYRK3 96 1
NEK2a 92 8
NEK6 103 1
IKK beta 104 12
IKK epsilon 84 16
TBK1 73 9
PIM1 91 7
PIM2 105 9
PIM3 53 4
SRPK1 58 3
EF2K 104 10
EIF2AK3 93 7
HIPK1 79 0
HIPK2 102 11
HIPK3 90 3
CLK2 91 12
PAK2 105 8
PAK4 82 13
PAK5 93 4
PAK6 105 2
MST2 85 1
MST3 73 6
MST4 82 6
GCK 91 6
MAP4K3 84 0
MAP4K5 65 8
MINK1 85 3
MEKK1 100 8
MLK1 18 1
MLK3 10 0
TESK1 79 8
TAO1 90 0
ASK1 112 21
TAK1 103 13
IRAK1 98 2
IRAK4 98 4
RIPK2 94 3
OSR1 105 8
TTK 82 2
MPSK1 98 7
WNK1 107 6
ULK1 77 6
ULK2 98 11
TGFBR1 110 16
Src 103 3
Lck 106 0
CSK 92 12
YES1 74 7
ABL 106 23
BTK 84 5
JAK2 113 0
SYK 81 12
ZAP70 98 4
TIE2 78 2
BRK 66 7
EPH-A2 104 16
EPH-A4 97 8
EPH-B1 91 5
EPH-B2 118 19
EPH-B3 74 7
EPH-B4 101 2
FGF-R1 102 13
HER4 95 4
IGF-1R 68 7
IR 98 4
IRR 85 1
TrkA 80 9
DDR2 112 13
VEGFR1 49 4
PDGFRA 106 2
PINK 96 2
Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 102 12
MKK2 93 0
MKK6 103 8
ERK1 101 22
ERK2 96 4
ERK5 95 1
JNK1 104 0
JNK2 98 3
JNK3 98 1
p38 alpha MAPK 103 9
p38 beta MAPK 94 1
p38 gamma MAPK 93 5
p38 delta MAPK 91 5
ERK8 79 4
RSK1 70 1
RSK2 90 2
PDK1 102 16
PKB alpha 91 2
PKB beta 82 8
SGK1 79 1
S6K1 69 2
PKA 98 6
ROCK 2 86 13
PRK2 113 25
PKC alpha 98 4
PKC gamma 83 5
PKC zeta 85 8
PKD1 102 13
STK33 79 5
MSK1 103 3
MNK1 73 11
MNK2 91 4
MAPKAP-K2 84 8
MAPKAP-K3 74 10
PRAK 88 1
CAMKK beta 40 1
CAMK1 66 10
SmMLCK 13 1
PHK 95 1
DAPK1 43 12
CHK1 113 1
CHK2 12 0
GSK3 beta 96 10
CDK2-Cyclin A 85 11
CDK9-Cyclin T1 97 0
PLK1 92 3
Aurora A 110 8
Aurora B 93 15
TLK1 109 2
LKB1 122 30
AMPK 113 16
AMPK (hum) 55 5
MARK1 95 14
MARK2 94 4
MARK3 100 12
MARK4 85 6
BRSK1 91 7
BRSK2 87 2
MELK 64 14
NUAK1 91 8
SIK2 84 2
SIK3 100 3
TSSK1 86 2
CK1 gamma 2 36 0
CK1 delta 85 4
CK2 65 3
TTBK1 107 12
TTBK2 86 8
DYRK1A 69 2
DYRK2 79 17
DYRK3 93 7
NEK2a 97 10
NEK6 108 0
IKK beta 96 8
IKK epsilon 28 4
TBK1 22 0
PIM1 67 1
PIM2 112 15
PIM3 14 0
SRPK1 16 1
EF2K 102 12
EIF2AK3 108 1
HIPK1 82 1
HIPK2 93 23
HIPK3 93 4
CLK2 88 12
PAK2 109 2
PAK4 98 3
PAK5 102 7
PAK6 110 3
MST2 84 4
MST3 92 11
MST4 89 11
GCK 87 2
MAP4K3 79 6
MAP4K5 46 0
MINK1 89 16
MEKK1 102 16
MLK1 6 2
MLK3 5 0
TESK1 86 6
TAO1 109 6
ASK1 116 6
TAK1 86 6
IRAK1 83 2
IRAK4 97 16
RIPK2 56 2
OSR1 103 8
TTK 67 0
MPSK1 99 6
WNK1 105 0
ULK1 93 8
ULK2 89 7
TGFBR1 98 10
Src 85 6
Lck 102 10
CSK 81 7
YES1 94 10
ABL 86 12
BTK 51 6
JAK2 74 0
SYK 79 10
ZAP70 109 7
TIE2 85 2
BRK 66 4
EPH-A2 98 9
EPH-A4 71 3
EPH-B1 102 1
EPH-B2 105 3
EPH-B3 95 13
EPH-B4 88 6
FGF-R1 96 13
HER4 73 8
IGF-1R 31 0
IR 36 2
IRR 53 1
TrkA 49 7
DDR2 90 4
VEGFR1 15 0
PDGFRA 84 12
PINK 102 10

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