Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Chloroquine C18H26ClN3 319.87214 Anti Malarial Download

Results as Barchart

View results as a bar chart
10µM
1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remainingsort ascending Standard Deviation
PKD1 133 19
CHK2 128 24
Src 127 13
GSK3 beta 127 12
EF2K 127 15
IGF-1R 126 30
PKC zeta 126 19
TGFBR1 123 13
ROCK 2 123 3
NUAK1 123 22
MKK6 122 22
MAP4K3 122 22
SIK2 121 1
SIK3 121 14
ULK1 121 4
JNK2 120 6
JNK3 120 16
MST2 120 2
PDK1 120 6
PAK2 119 12
p38 beta MAPK 119 25
EPH-A2 119 11
Aurora B 119 8
MARK1 118 2
STK33 118 15
HIPK2 117 4
TESK1 117 18
BTK 117 26
SYK 117 7
RIPK2 117 9
EPH-B1 117 17
FGF-R1 116 20
HIPK1 115 13
MLK1 115 9
EPH-B4 115 6
SGK1 115 2
HER4 115 22
TAK1 115 1
PLK1 115 23
LKB1 114 10
TAO1 114 6
MARK4 114 4
JAK2 114 8
CDK2-Cyclin A 114 19
SRPK1 114 20
MAPKAP-K3 113 6
EIF2AK3 113 7
CAMKK beta 113 16
DYRK3 113 14
IRAK1 113 7
p38 gamma MAPK 113 1
GCK 113 3
RSK1 113 4
RSK2 113 1
DYRK1A 112 2
MARK3 112 1
PKC gamma 112 1
MEKK1 111 11
AMPK 111 17
TTBK1 111 3
CLK2 111 1
IR 111 6
PRK2 111 16
PAK6 111 2
ERK1 110 3
DAPK1 110 15
NEK6 110 4
MLK3 109 7
Lck 109 15
PAK4 109 3
IRAK4 109 7
PINK 109 9
CK1 gamma 2 109 0
TTBK2 108 1
ABL 108 6
DDR2 108 3
MELK 108 15
OSR1 108 12
TTK 108 2
Aurora A 108 7
MKK1 108 24
PKB alpha 107 12
SmMLCK 107 16
MSK1 107 8
AMPK (hum) 106 4
ERK2 106 8
MAP4K5 106 13
TrkA 105 2
p38 delta MAPK 105 16
MPSK1 105 1
WNK1 105 5
DYRK2 104 0
VEGFR1 104 8
S6K1 103 12
CSK 103 7
p38 alpha MAPK 103 12
IKK beta 103 9
PDGFRA 103 7
EPH-B3 102 7
CAMK1 102 5
MARK2 102 20
MST4 102 3
TLK1 102 8
EPH-B2 102 7
JNK1 101 3
ASK1 101 15
PAK5 101 11
PIM2 101 19
ERK5 100 2
BRSK2 100 24
PIM3 100 1
CK2 99 8
CDK9-Cyclin T1 99 28
PIM1 99 3
PKA 98 1
IRR 98 8
CHK1 98 3
MKK2 97 16
TBK1 97 15
ERK8 97 6
CK1 delta 96 2
MNK1 95 33
ULK2 95 37
BRSK1 94 7
MINK1 94 5
ZAP70 92 3
EPH-A4 92 9
MNK2 92 24
MAPKAP-K2 92 13
HIPK3 91 11
PKB beta 90 1
PRAK 89 18
TSSK1 89 8
BRK 88 8
YES1 85 4
MST3 85 19
TIE2 84 1
PKC alpha 81 24
NEK2a 79 5
IKK epsilon 79 2
PHK 76 4
Screening Concentration: 10µM
Kinase % Activity Remainingsort ascending Standard Deviation
MKK6 130 15
PKD1 129 44
HIPK2 128 4
Aurora B 126 2
EPH-B1 125 27
SIK3 125 7
EF2K 124 5
TTBK1 124 2
BTK 124 8
MNK2 123 5
PKC zeta 121 6
STK33 121 24
CDK9-Cyclin T1 121 12
PLK1 121 2
WNK1 119 3
CK2 119 3
HER4 119 23
JAK2 119 17
CHK2 119 28
TGFBR1 118 18
TESK1 118 15
PAK2 118 7
RSK2 117 2
PKB beta 117 37
DDR2 117 5
MAP4K5 116 11
TAK1 116 1
JNK3 116 10
GSK3 beta 116 3
MNK1 115 0
MKK2 115 21
RIPK2 115 2
GCK 115 9
MAP4K3 114 16
ROCK 2 114 1
SIK2 114 8
CK1 gamma 2 112 5
PDK1 112 0
MINK1 112 17
TTBK2 112 0
IGF-1R 112 25
IRAK4 112 3
RSK1 111 5
Aurora A 111 27
SRPK1 111 1
AMPK 111 19
FGF-R1 111 8
PKC gamma 111 1
PAK6 111 4
SYK 111 1
PIM2 111 26
VEGFR1 110 15
OSR1 110 13
PDGFRA 110 6
TTK 110 1
MAPKAP-K2 109 1
EPH-B3 109 3
MLK1 109 1
SGK1 109 14
Lck 109 16
ERK5 109 12
CLK2 109 5
NUAK1 109 5
PINK 109 23
ULK1 108 11
MEKK1 108 5
ERK1 108 7
MARK2 108 6
BRSK2 108 19
p38 gamma MAPK 108 9
MPSK1 108 15
EIF2AK3 107 12
HIPK1 107 9
DYRK1A 107 8
JNK2 107 13
MST2 107 3
DYRK3 106 8
IRR 106 27
CHK1 106 10
p38 beta MAPK 106 10
MST4 106 2
TSSK1 105 6
MAPKAP-K3 105 18
Src 105 2
AMPK (hum) 105 4
TAO1 105 11
ULK2 104 2
CAMKK beta 104 14
MLK3 104 4
CAMK1 104 5
MELK 104 10
BRK 104 6
ERK8 104 5
TLK1 103 7
SmMLCK 103 20
ASK1 103 5
PRK2 103 3
PKC alpha 103 10
p38 delta MAPK 103 1
PKA 102 8
NEK6 102 0
ZAP70 102 2
ERK2 101 3
HIPK3 101 11
ABL 101 10
MARK4 101 5
NEK2a 101 31
MSK1 101 3
EPH-A4 100 8
MKK1 100 17
EPH-B2 100 11
CSK 100 5
YES1 100 7
JNK1 100 9
IR 100 11
IKK epsilon 100 22
EPH-A2 100 9
IRAK1 99 2
TrkA 99 15
CDK2-Cyclin A 99 8
PKB alpha 98 1
MST3 98 5
EPH-B4 97 21
MARK3 97 14
PAK5 97 9
PIM3 96 2
MARK1 96 9
TBK1 96 11
p38 alpha MAPK 95 13
S6K1 94 1
DAPK1 94 7
BRSK1 93 22
CK1 delta 92 5
PAK4 91 9
LKB1 90 7
PIM1 90 6
DYRK2 89 0
PRAK 84 7
PHK 83 26
TIE2 81 8
IKK beta 76 4

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