Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Chloroquine C18H26ClN3 319.87214 Anti Malarial Download

Results as Barchart

View results as a bar chart
10µM
1µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 100 17
MKK2 115 21
MKK6 130 15
ERK1 108 7
ERK2 101 3
ERK5 109 12
JNK1 100 9
JNK2 107 13
JNK3 116 10
p38 alpha MAPK 95 13
p38 beta MAPK 106 10
p38 gamma MAPK 108 9
p38 delta MAPK 103 1
ERK8 104 5
RSK1 111 5
RSK2 117 2
PDK1 112 0
PKB alpha 98 1
PKB beta 117 37
SGK1 109 14
S6K1 94 1
PKA 102 8
ROCK 2 114 1
PRK2 103 3
PKC alpha 103 10
PKC gamma 111 1
PKC zeta 121 6
PKD1 129 44
STK33 121 24
MSK1 101 3
MNK1 115 0
MNK2 123 5
MAPKAP-K2 109 1
MAPKAP-K3 105 18
PRAK 84 7
CAMKK beta 104 14
CAMK1 104 5
SmMLCK 103 20
PHK 83 26
DAPK1 94 7
CHK1 106 10
CHK2 119 28
GSK3 beta 116 3
CDK2-Cyclin A 99 8
CDK9-Cyclin T1 121 12
PLK1 121 2
Aurora A 111 27
Aurora B 126 2
TLK1 103 7
LKB1 90 7
AMPK 111 19
AMPK (hum) 105 4
MARK1 96 9
MARK2 108 6
MARK3 97 14
MARK4 101 5
BRSK1 93 22
BRSK2 108 19
MELK 104 10
NUAK1 109 5
SIK2 114 8
SIK3 125 7
TSSK1 105 6
CK1 gamma 2 112 5
CK1 delta 92 5
CK2 119 3
TTBK1 124 2
TTBK2 112 0
DYRK1A 107 8
DYRK2 89 0
DYRK3 106 8
NEK2a 101 31
NEK6 102 0
IKK beta 76 4
IKK epsilon 100 22
TBK1 96 11
PIM1 90 6
PIM2 111 26
PIM3 96 2
SRPK1 111 1
EF2K 124 5
EIF2AK3 107 12
HIPK1 107 9
HIPK2 128 4
HIPK3 101 11
CLK2 109 5
PAK2 118 7
PAK4 91 9
PAK5 97 9
PAK6 111 4
MST2 107 3
MST3 98 5
MST4 106 2
GCK 115 9
MAP4K3 114 16
MAP4K5 116 11
MINK1 112 17
MEKK1 108 5
MLK1 109 1
MLK3 104 4
TESK1 118 15
TAO1 105 11
ASK1 103 5
TAK1 116 1
IRAK1 99 2
IRAK4 112 3
RIPK2 115 2
OSR1 110 13
TTK 110 1
MPSK1 108 15
WNK1 119 3
ULK1 108 11
ULK2 104 2
TGFBR1 118 18
Src 105 2
Lck 109 16
CSK 100 5
YES1 100 7
ABL 101 10
BTK 124 8
JAK2 119 17
SYK 111 1
ZAP70 102 2
TIE2 81 8
BRK 104 6
EPH-A2 100 9
EPH-A4 100 8
EPH-B1 125 27
EPH-B2 100 11
EPH-B3 109 3
EPH-B4 97 21
FGF-R1 111 8
HER4 119 23
IGF-1R 112 25
IR 100 11
IRR 106 27
TrkA 99 15
DDR2 117 5
VEGFR1 110 15
PDGFRA 110 6
PINK 109 23
Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 108 24
MKK2 97 16
MKK6 122 22
ERK1 110 3
ERK2 106 8
ERK5 100 2
JNK1 101 3
JNK2 120 6
JNK3 120 16
p38 alpha MAPK 103 12
p38 beta MAPK 119 25
p38 gamma MAPK 113 1
p38 delta MAPK 105 16
ERK8 97 6
RSK1 113 4
RSK2 113 1
PDK1 120 6
PKB alpha 107 12
PKB beta 90 1
SGK1 115 2
S6K1 103 12
PKA 98 1
ROCK 2 123 3
PRK2 111 16
PKC alpha 81 24
PKC gamma 112 1
PKC zeta 126 19
PKD1 133 19
STK33 118 15
MSK1 107 8
MNK1 95 33
MNK2 92 24
MAPKAP-K2 92 13
MAPKAP-K3 113 6
PRAK 89 18
CAMKK beta 113 16
CAMK1 102 5
SmMLCK 107 16
PHK 76 4
DAPK1 110 15
CHK1 98 3
CHK2 128 24
GSK3 beta 127 12
CDK2-Cyclin A 114 19
CDK9-Cyclin T1 99 28
PLK1 115 23
Aurora A 108 7
Aurora B 119 8
TLK1 102 8
LKB1 114 10
AMPK 111 17
AMPK (hum) 106 4
MARK1 118 2
MARK2 102 20
MARK3 112 1
MARK4 114 4
BRSK1 94 7
BRSK2 100 24
MELK 108 15
NUAK1 123 22
SIK2 121 1
SIK3 121 14
TSSK1 89 8
CK1 gamma 2 109 0
CK1 delta 96 2
CK2 99 8
TTBK1 111 3
TTBK2 108 1
DYRK1A 112 2
DYRK2 104 0
DYRK3 113 14
NEK2a 79 5
NEK6 110 4
IKK beta 103 9
IKK epsilon 79 2
TBK1 97 15
PIM1 99 3
PIM2 101 19
PIM3 100 1
SRPK1 114 20
EF2K 127 15
EIF2AK3 113 7
HIPK1 115 13
HIPK2 117 4
HIPK3 91 11
CLK2 111 1
PAK2 119 12
PAK4 109 3
PAK5 101 11
PAK6 111 2
MST2 120 2
MST3 85 19
MST4 102 3
GCK 113 3
MAP4K3 122 22
MAP4K5 106 13
MINK1 94 5
MEKK1 111 11
MLK1 115 9
MLK3 109 7
TESK1 117 18
TAO1 114 6
ASK1 101 15
TAK1 115 1
IRAK1 113 7
IRAK4 109 7
RIPK2 117 9
OSR1 108 12
TTK 108 2
MPSK1 105 1
WNK1 105 5
ULK1 121 4
ULK2 95 37
TGFBR1 123 13
Src 127 13
Lck 109 15
CSK 103 7
YES1 85 4
ABL 108 6
BTK 117 26
JAK2 114 8
SYK 117 7
ZAP70 92 3
TIE2 84 1
BRK 88 8
EPH-A2 119 11
EPH-A4 92 9
EPH-B1 117 17
EPH-B2 102 7
EPH-B3 102 7
EPH-B4 115 6
FGF-R1 116 20
HER4 115 22
IGF-1R 126 30
IR 111 6
IRR 98 8
TrkA 105 2
DDR2 108 3
VEGFR1 104 8
PDGFRA 103 7
PINK 109 9

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