Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
2-Aminopurine C5H5N5 135.1267 PKR Sigma Download

Results as Barchart

View results as a bar chart
100µM

Results as Table

Screening Concentration: 100µM
Kinase % Activity Remaining Standard Deviation
MKK1 56 5
MKK2 63 2
MKK6 91 6
ERK1 78 8
ERK2 78 0
ERK5 67 1
JNK1 81 6
JNK2 83 8
JNK3 83 6
p38 alpha MAPK 85 4
p38 beta MAPK 83 0
p38 gamma MAPK 75 0
p38 delta MAPK 97 6
ERK8 79 10
RSK1 81 2
RSK2 79 8
PDK1 67 1
PKB alpha 99 5
PKB beta 83 7
SGK1 63 1
S6K1 85 15
PKA 93 7
ROCK 2 64 2
PRK2 73 8
PKC alpha 104 27
PKC gamma 84 6
PKC zeta 78 3
PKD1 65 7
STK33 67 6
MSK1 84 4
MNK1 67 7
MNK2 75 2
MAPKAP-K2 40 3
MAPKAP-K3 70 3
PRAK 75 0
CAMKK beta 87 1
CAMK1 85 5
SmMLCK 75 2
PHK 76 2
DAPK1 77 7
CHK1 57 9
CHK2 21 0
GSK3 beta 89 12
CDK2-Cyclin A 81 2
CDK9-Cyclin T1 72 9
PLK1 76 1
Aurora A 64 3
Aurora B 23 2
TLK1 108 7
LKB1 82 9
AMPK 73 6
AMPK (hum) 80 11
MARK1 67 0
MARK2 69 2
MARK3 61 5
MARK4 74 5
BRSK1 79 8
BRSK2 81 3
MELK 63 2
NUAK1 33 0
SIK2 43 2
SIK3 56 2
TSSK1 44 8
CK1 gamma 2 16 1
CK1 delta 24 4
CK2 89 5
TTBK1 80 12
TTBK2 74 6
DYRK1A 64 3
DYRK2 68 6
DYRK3 72 5
NEK2a 60 14
NEK6 88 10
IKK beta 55 4
IKK epsilon 62 5
TBK1 73 4
PIM1 122 0
PIM2 102 7
PIM3 76 4
SRPK1 96 1
EF2K 88 3
EIF2AK3 89 0
HIPK1 104 15
HIPK2 76 2
HIPK3 92 2
CLK2 37 4
PAK2 100 10
PAK4 44 5
PAK5 64 0
PAK6 82 5
MST2 63 1
MST3 81 2
MST4 72 3
GCK 20 0
MAP4K3 50 6
MAP4K5 67 3
MINK1 63 3
MEKK1 78 0
MLK1 29 6
MLK3 18 5
TESK1 60 4
TAO1 66 3
ASK1 44 3
TAK1 54 2
IRAK1 65 10
IRAK4 76 7
RIPK2 43 1
OSR1 80 7
TTK 82 1
MPSK1 89 4
WNK1 87 2
ULK1 57 2
ULK2 69 0
TGFBR1 101 2
Src 73 1
Lck 79 3
CSK 91 17
YES1 94 6
ABL 83 7
BTK 67 3
JAK2 30 0
SYK 102 8
ZAP70 101 4
TIE2 85 1
BRK 47 5
EPH-A2 83 1
EPH-A4 84 4
EPH-B1 108 7
EPH-B2 95 10
EPH-B3 105 36
EPH-B4 90 10
FGF-R1 109 18
HER4 72 0
IGF-1R 75 23
IR 106 8
IRR 73 5
TrkA 73 13
DDR2 82 11
VEGFR1 29 3
PDGFRA 79 3
PINK 90 11

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