Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Kalopanaxsaponin A C41H66O12 750.96 Download

Results as Barchart

View results as a bar chart
10µM
1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 91 11
MKK2 90 1
MKK6 83 4
ERK1 107 6
ERK2 94 2
ERK5 100 2
JNK1 94 0
JNK2 93 1
JNK3 91 8
p38 alpha MAPK 104 4
p38 beta MAPK 102 3
p38 gamma MAPK 102 4
p38 delta MAPK 96 1
ERK8 102 6
RSK1 110 1
RSK2 84 2
PDK1 103 5
PKB alpha 106 1
PKB beta 108 11
SGK1 92 14
S6K1 99 4
PKA 104 4
ROCK 2 91 3
PRK2 86 1
PKC alpha 108 20
PKC gamma 93 0
PKC zeta 98 1
PKD1 115 37
STK33 106 11
MSK1 100 2
MNK1 97 5
MNK2 101 10
MAPKAP-K2 86 3
MAPKAP-K3 84 8
PRAK 88 3
CAMKK beta 88 20
CAMK1 113 11
SmMLCK 98 5
PHK 96 10
DAPK1 97 2
CHK1 94 2
CHK2 103 2
GSK3 beta 108 5
CDK2-Cyclin A 95 8
CDK9-Cyclin T1 92 4
PLK1 95 12
Aurora A 102 11
Aurora B 111 30
TLK1 115 5
LKB1 103 7
AMPK 100 5
AMPK (hum) 107 16
MARK1 81 6
MARK2 88 9
MARK3 95 8
MARK4 85 11
BRSK1 100 5
BRSK2 94 10
MELK 87 4
NUAK1 76 3
SIK2 92 3
SIK3 93 1
TSSK1 89 2
CK1 gamma 2 93 3
CK1 delta 94 3
CK2 101 5
TTBK1 101 19
TTBK2 118 5
DYRK1A 103 16
DYRK2 108 4
DYRK3 94 21
NEK2a 100 3
NEK6 100 11
IKK beta 95 15
IKK epsilon 82 2
TBK1 103 4
PIM1 134 4
PIM2 97 10
PIM3 85 3
SRPK1 102 3
EF2K 108 14
EIF2AK3 115 6
HIPK1 116 10
HIPK2 116 0
HIPK3 97 8
CLK2 91 6
PAK2 104 12
PAK4 112 12
PAK5 84 4
PAK6 100 2
MST2 90 10
MST3 95 18
MST4 97 1
GCK 93 10
MAP4K3 85 12
MAP4K5 110 19
MINK1 81 9
MEKK1 89 1
MLK1 93 28
MLK3 101 4
TESK1 104 11
TAO1 95 3
ASK1 104 7
TAK1 115 19
IRAK1 112 3
IRAK4 115 4
RIPK2 104 1
OSR1 101 4
TTK 109 3
MPSK1 91 5
WNK1 97 2
ULK1 89 7
ULK2 98 3
TGFBR1 97 2
Src 110 3
Lck 104 1
CSK 121 12
YES1 106 6
ABL 109 0
BTK 114 21
JAK2 93 12
SYK 105 2
ZAP70 107 0
TIE2 94 0
BRK 107 7
EPH-A2 104 6
EPH-A4 93 8
EPH-B1 104 13
EPH-B2 112 3
EPH-B3 123 29
EPH-B4 119 5
FGF-R1 108 1
HER4 125 8
IGF-1R 106 27
IR 120 2
IRR 96 4
TrkA 110 9
DDR2 99 16
VEGFR1 78 3
PDGFRA 91 10
PINK 112 11
Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 99 13
MKK2 97 8
MKK6 86 9
ERK1 114 16
ERK2 99 9
ERK5 109 5
JNK1 117 12
JNK2 108 4
JNK3 90 4
p38 alpha MAPK 103 3
p38 beta MAPK 98 1
p38 gamma MAPK 100 0
p38 delta MAPK 99 2
ERK8 106 11
RSK1 92 1
RSK2 88 29
PDK1 109 12
PKB alpha 109 2
PKB beta 93 2
SGK1 124 16
S6K1 94 15
PKA 107 14
ROCK 2 105 11
PRK2 105 1
PKC alpha 114 18
PKC gamma 92 5
PKC zeta 112 7
PKD1 141 2
STK33 121 0
MSK1 122 2
MNK1 97 6
MNK2 102 11
MAPKAP-K2 88 18
MAPKAP-K3 92 3
PRAK 94 4
CAMKK beta 89 1
CAMK1 96 17
SmMLCK 95 7
PHK 102 9
DAPK1 116 0
CHK1 94 6
CHK2 106 11
GSK3 beta 107 4
CDK2-Cyclin A 89 2
CDK9-Cyclin T1 112 6
PLK1 101 1
Aurora A 109 8
Aurora B 121 26
TLK1 115 8
LKB1 97 0
AMPK 106 3
AMPK (hum) 115 10
MARK1 87 15
MARK2 89 5
MARK3 100 15
MARK4 91 8
BRSK1 113 10
BRSK2 89 4
MELK 97 3
NUAK1 85 8
SIK2 113 11
SIK3 81 3
TSSK1 97 5
CK1 gamma 2 98 11
CK1 delta 105 11
CK2 101 2
TTBK1 131 9
TTBK2 113 1
DYRK1A 100 8
DYRK2 114 18
DYRK3 108 1
NEK2a 101 1
NEK6 108 11
IKK beta 97 12
IKK epsilon 122 18
TBK1 97 5
PIM1 138 12
PIM2 102 10
PIM3 87 15
SRPK1 96 10
EF2K 101 3
EIF2AK3 111 15
HIPK1 111 9
HIPK2 116 6
HIPK3 98 13
CLK2 96 1
PAK2 107 10
PAK4 132 0
PAK5 88 7
PAK6 106 2
MST2 107 11
MST3 134 27
MST4 111 12
GCK 100 6
MAP4K3 94 8
MAP4K5 109 7
MINK1 96 2
MEKK1 117 12
MLK1 108 13
MLK3 115 21
TESK1 113 8
TAO1 100 1
ASK1 102 11
TAK1 109 6
IRAK1 108 2
IRAK4 119 5
RIPK2 108 0
OSR1 117 9
TTK 114 23
MPSK1 98 17
WNK1 97 3
ULK1 100 8
ULK2 108 2
TGFBR1 111 11
Src 144 33
Lck 62 7
CSK 133 8
YES1 123 3
ABL 109 10
BTK 141 32
JAK2 104 13
SYK 128 25
ZAP70 121 5
TIE2 82 3
BRK 101 10
EPH-A2 110 6
EPH-A4 99 4
EPH-B1 96 11
EPH-B2 113 12
EPH-B3 92 20
EPH-B4 131 6
FGF-R1 106 1
HER4 108 39
IGF-1R 122 5
IR 122 8
IRR 103 9
TrkA 117 6
DDR2 109 8
VEGFR1 86 5
PDGFRA 106 8
PINK 124 10

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