InhibitorScreening ConcentrationKinase% Activity RemainingStandard Deviation
Amgen TBK 1 inhibitor (Compound II)0.10µMMKK1408
Amgen TBK 1 inhibitor (Compound II)0.10µMMKK2557
Amgen TBK 1 inhibitor (Compound II)0.10µMMKK6995
Amgen TBK 1 inhibitor (Compound II)0.10µMERK111112
Amgen TBK 1 inhibitor (Compound II)0.10µMERK28413
Amgen TBK 1 inhibitor (Compound II)0.10µMJNK18913
Amgen TBK 1 inhibitor (Compound II)0.10µMJNK28521
Amgen TBK 1 inhibitor (Compound II)0.10µMJNK36513
Amgen TBK 1 inhibitor (Compound II)0.10µMp38 alpha MAPK984
Amgen TBK 1 inhibitor (Compound II)0.10µMp38 beta MAPK1032
Amgen TBK 1 inhibitor (Compound II)0.10µMp38 gamma MAPK11316
Amgen TBK 1 inhibitor (Compound II)0.10µMp38 delta MAPK9321
Amgen TBK 1 inhibitor (Compound II)0.10µMERK8226
Amgen TBK 1 inhibitor (Compound II)0.10µMRSK16244
Amgen TBK 1 inhibitor (Compound II)0.10µMRSK2381
Amgen TBK 1 inhibitor (Compound II)0.10µMPDK1964
Amgen TBK 1 inhibitor (Compound II)0.10µMPKB alpha 9912
Amgen TBK 1 inhibitor (Compound II)0.10µMPKB beta 8817
Amgen TBK 1 inhibitor (Compound II)0.10µMSGK110710
Amgen TBK 1 inhibitor (Compound II)0.10µMS6K17015
Amgen TBK 1 inhibitor (Compound II)0.10µMPKA7811
Amgen TBK 1 inhibitor (Compound II)0.10µMROCK 2495
Amgen TBK 1 inhibitor (Compound II)0.10µMPRK2573
Amgen TBK 1 inhibitor (Compound II)0.10µMPKC alpha 9515
Amgen TBK 1 inhibitor (Compound II)0.10µMPKC gamma 1177
Amgen TBK 1 inhibitor (Compound II)0.10µMPKC zeta 9421
Amgen TBK 1 inhibitor (Compound II)0.10µMPKD11000
Amgen TBK 1 inhibitor (Compound II)0.10µMSTK33302
Amgen TBK 1 inhibitor (Compound II)0.10µMMSK1768
Amgen TBK 1 inhibitor (Compound II)0.10µMMNK1595
Amgen TBK 1 inhibitor (Compound II)0.10µMMNK2679
Amgen TBK 1 inhibitor (Compound II)0.10µMMAPKAP-K2 10525
Amgen TBK 1 inhibitor (Compound II)0.10µMMAPKAP-K3973
Amgen TBK 1 inhibitor (Compound II)0.10µMPRAK9812
Amgen TBK 1 inhibitor (Compound II)0.10µMCAMKK beta 584
Amgen TBK 1 inhibitor (Compound II)0.10µMCAMK1672
Amgen TBK 1 inhibitor (Compound II)0.10µMSmMLCK1006
Amgen TBK 1 inhibitor (Compound II)0.10µMPHK561
Amgen TBK 1 inhibitor (Compound II)0.10µMDAPK1515
Amgen TBK 1 inhibitor (Compound II)0.10µMCHK1720
Amgen TBK 1 inhibitor (Compound II)0.10µMCHK2480
Amgen TBK 1 inhibitor (Compound II)0.10µMGSK3 beta 376
Amgen TBK 1 inhibitor (Compound II)0.10µMCDK2-Cyclin A342
Amgen TBK 1 inhibitor (Compound II)0.10µMPLK19011
Amgen TBK 1 inhibitor (Compound II)0.10µMAurora A183
Amgen TBK 1 inhibitor (Compound II)0.10µMAurora B361
Amgen TBK 1 inhibitor (Compound II)0.10µMTLK1791
Amgen TBK 1 inhibitor (Compound II)0.10µMLKB111914
Amgen TBK 1 inhibitor (Compound II)0.10µMAMPK254
Amgen TBK 1 inhibitor (Compound II)0.10µMMARK1636
Amgen TBK 1 inhibitor (Compound II)0.10µMMARK2674
Amgen TBK 1 inhibitor (Compound II)0.10µMMARK3419
Amgen TBK 1 inhibitor (Compound II)0.10µMMARK49224
Amgen TBK 1 inhibitor (Compound II)0.10µMBRSK1742
Amgen TBK 1 inhibitor (Compound II)0.10µMBRSK2845
Amgen TBK 1 inhibitor (Compound II)0.10µMMELK370
Amgen TBK 1 inhibitor (Compound II)0.10µMNUAK1162
Amgen TBK 1 inhibitor (Compound II)0.10µMTSSK1317
Amgen TBK 1 inhibitor (Compound II)0.10µMCK1 delta 951
Amgen TBK 1 inhibitor (Compound II)0.10µMCK2332
Amgen TBK 1 inhibitor (Compound II)0.10µMTTBK110411
Amgen TBK 1 inhibitor (Compound II)0.10µMDYRK1A573
Amgen TBK 1 inhibitor (Compound II)0.10µMDYRK2505
Amgen TBK 1 inhibitor (Compound II)0.10µMDYRK37530
Amgen TBK 1 inhibitor (Compound II)0.10µMNEK2a222
Amgen TBK 1 inhibitor (Compound II)0.10µMNEK6892
Amgen TBK 1 inhibitor (Compound II)0.10µMIKK beta 868
Amgen TBK 1 inhibitor (Compound II)0.10µMIKK epsilon 286
Amgen TBK 1 inhibitor (Compound II)0.10µMTBK1140
Amgen TBK 1 inhibitor (Compound II)0.10µMPIM19617
Amgen TBK 1 inhibitor (Compound II)0.10µMPIM210816
Amgen TBK 1 inhibitor (Compound II)0.10µMPIM3916
Amgen TBK 1 inhibitor (Compound II)0.10µMSRPK11044
Amgen TBK 1 inhibitor (Compound II)0.10µMEF2K10013
Amgen TBK 1 inhibitor (Compound II)0.10µMEIF2AK39020
Amgen TBK 1 inhibitor (Compound II)0.10µMHIPK14413
Amgen TBK 1 inhibitor (Compound II)0.10µMHIPK23111
Amgen TBK 1 inhibitor (Compound II)0.10µMHIPK36912
Amgen TBK 1 inhibitor (Compound II)0.10µMCLK23010
Amgen TBK 1 inhibitor (Compound II)0.10µMPAK25014
Amgen TBK 1 inhibitor (Compound II)0.10µMPAK4291
Amgen TBK 1 inhibitor (Compound II)0.10µMPAK5530
Amgen TBK 1 inhibitor (Compound II)0.10µMPAK6628
Amgen TBK 1 inhibitor (Compound II)0.10µMMST2785
Amgen TBK 1 inhibitor (Compound II)0.10µMMST49018
Amgen TBK 1 inhibitor (Compound II)0.10µMGCK299
Amgen TBK 1 inhibitor (Compound II)0.10µMMINK110414
Amgen TBK 1 inhibitor (Compound II)0.10µMMEKK11037
Amgen TBK 1 inhibitor (Compound II)0.10µMMLK171
Amgen TBK 1 inhibitor (Compound II)0.10µMMLK3155
Amgen TBK 1 inhibitor (Compound II)0.10µMTESK15910
Amgen TBK 1 inhibitor (Compound II)0.10µMTAO1957
Amgen TBK 1 inhibitor (Compound II)0.10µMASK1993
Amgen TBK 1 inhibitor (Compound II)0.10µMTAK1143
Amgen TBK 1 inhibitor (Compound II)0.10µMIRAK1193
Amgen TBK 1 inhibitor (Compound II)0.10µMIRAK46411
Amgen TBK 1 inhibitor (Compound II)0.10µMRIPK2285
Amgen TBK 1 inhibitor (Compound II)0.10µMOSR110114
Amgen TBK 1 inhibitor (Compound II)0.10µMTTK811
Amgen TBK 1 inhibitor (Compound II)0.10µMMPSK11011
Amgen TBK 1 inhibitor (Compound II)0.10µMSrc71
Amgen TBK 1 inhibitor (Compound II)0.10µMLck102
Amgen TBK 1 inhibitor (Compound II)0.10µMCSK655
Amgen TBK 1 inhibitor (Compound II)0.10µMYES1169
Amgen TBK 1 inhibitor (Compound II)0.10µMABL312
Amgen TBK 1 inhibitor (Compound II)0.10µMBTK222
Amgen TBK 1 inhibitor (Compound II)0.10µMJAK240
Amgen TBK 1 inhibitor (Compound II)0.10µMSYK587
Amgen TBK 1 inhibitor (Compound II)0.10µMZAP70541
Amgen TBK 1 inhibitor (Compound II)0.10µMTIE2604
Amgen TBK 1 inhibitor (Compound II)0.10µMBRK464
Amgen TBK 1 inhibitor (Compound II)0.10µMEPH-A22812
Amgen TBK 1 inhibitor (Compound II)0.10µMEPH-A4140
Amgen TBK 1 inhibitor (Compound II)0.10µMEPH-B180
Amgen TBK 1 inhibitor (Compound II)0.10µMEPH-B22311
Amgen TBK 1 inhibitor (Compound II)0.10µMEPH-B38616
Amgen TBK 1 inhibitor (Compound II)0.10µMEPH-B46913
Amgen TBK 1 inhibitor (Compound II)0.10µMFGF-R1201
Amgen TBK 1 inhibitor (Compound II)0.10µMHER4604
Amgen TBK 1 inhibitor (Compound II)0.10µMIGF-1R10419
Amgen TBK 1 inhibitor (Compound II)0.10µMIR794
Amgen TBK 1 inhibitor (Compound II)0.10µMIRR789
Amgen TBK 1 inhibitor (Compound II)0.10µMTrkA324
Amgen TBK 1 inhibitor (Compound II)0.10µMVEGFR151
Amgen TBK 1 inhibitor (Compound II)1.00µMMKK1132
Amgen TBK 1 inhibitor (Compound II)1.00µMMKK2284
Amgen TBK 1 inhibitor (Compound II)1.00µMMKK6754
Amgen TBK 1 inhibitor (Compound II)1.00µMERK1820
Amgen TBK 1 inhibitor (Compound II)1.00µMERK2575
Amgen TBK 1 inhibitor (Compound II)1.00µMJNK1380
Amgen TBK 1 inhibitor (Compound II)1.00µMJNK2331
Amgen TBK 1 inhibitor (Compound II)1.00µMJNK3390
Amgen TBK 1 inhibitor (Compound II)1.00µMp38 alpha MAPK8512
Amgen TBK 1 inhibitor (Compound II)1.00µMp38 beta MAPK9514
Amgen TBK 1 inhibitor (Compound II)1.00µMp38 gamma MAPK951
Amgen TBK 1 inhibitor (Compound II)1.00µMp38 delta MAPK682
Amgen TBK 1 inhibitor (Compound II)1.00µMERK841
Amgen TBK 1 inhibitor (Compound II)1.00µMRSK170
Amgen TBK 1 inhibitor (Compound II)1.00µMRSK291
Amgen TBK 1 inhibitor (Compound II)1.00µMPDK1363
Amgen TBK 1 inhibitor (Compound II)1.00µMPKB alpha 897
Amgen TBK 1 inhibitor (Compound II)1.00µMPKB beta 770
Amgen TBK 1 inhibitor (Compound II)1.00µMSGK1611
Amgen TBK 1 inhibitor (Compound II)1.00µMS6K1283
Amgen TBK 1 inhibitor (Compound II)1.00µMPKA265
Amgen TBK 1 inhibitor (Compound II)1.00µMROCK 2255
Amgen TBK 1 inhibitor (Compound II)1.00µMPRK2274
Amgen TBK 1 inhibitor (Compound II)1.00µMPKC alpha 569
Amgen TBK 1 inhibitor (Compound II)1.00µMPKC gamma 7119
Amgen TBK 1 inhibitor (Compound II)1.00µMPKC zeta 785
Amgen TBK 1 inhibitor (Compound II)1.00µMPKD1486
Amgen TBK 1 inhibitor (Compound II)1.00µMSTK33233
Amgen TBK 1 inhibitor (Compound II)1.00µMMSK1344
Amgen TBK 1 inhibitor (Compound II)1.00µMMNK1170
Amgen TBK 1 inhibitor (Compound II)1.00µMMNK2175
Amgen TBK 1 inhibitor (Compound II)1.00µMMAPKAP-K2 1085
Amgen TBK 1 inhibitor (Compound II)1.00µMMAPKAP-K38112
Amgen TBK 1 inhibitor (Compound II)1.00µMPRAK851
Amgen TBK 1 inhibitor (Compound II)1.00µMCAMKK beta 281
Amgen TBK 1 inhibitor (Compound II)1.00µMCAMK1262
Amgen TBK 1 inhibitor (Compound II)1.00µMSmMLCK7211
Amgen TBK 1 inhibitor (Compound II)1.00µMPHK121
Amgen TBK 1 inhibitor (Compound II)1.00µMDAPK1151
Amgen TBK 1 inhibitor (Compound II)1.00µMCHK1201
Amgen TBK 1 inhibitor (Compound II)1.00µMCHK2122
Amgen TBK 1 inhibitor (Compound II)1.00µMGSK3 beta 61
Amgen TBK 1 inhibitor (Compound II)1.00µMCDK2-Cyclin A71
Amgen TBK 1 inhibitor (Compound II)1.00µMPLK1917
Amgen TBK 1 inhibitor (Compound II)1.00µMAurora A31
Amgen TBK 1 inhibitor (Compound II)1.00µMAurora B113
Amgen TBK 1 inhibitor (Compound II)1.00µMTLK1390
Amgen TBK 1 inhibitor (Compound II)1.00µMLKB1732
Amgen TBK 1 inhibitor (Compound II)1.00µMAMPK220
Amgen TBK 1 inhibitor (Compound II)1.00µMMARK13114
Amgen TBK 1 inhibitor (Compound II)1.00µMMARK2289
Amgen TBK 1 inhibitor (Compound II)1.00µMMARK3161
Amgen TBK 1 inhibitor (Compound II)1.00µMMARK4245
Amgen TBK 1 inhibitor (Compound II)1.00µMBRSK1171
Amgen TBK 1 inhibitor (Compound II)1.00µMBRSK2357
Amgen TBK 1 inhibitor (Compound II)1.00µMMELK274
Amgen TBK 1 inhibitor (Compound II)1.00µMNUAK1131
Amgen TBK 1 inhibitor (Compound II)1.00µMTSSK150
Amgen TBK 1 inhibitor (Compound II)1.00µMCK1 delta 698
Amgen TBK 1 inhibitor (Compound II)1.00µMCK265
Amgen TBK 1 inhibitor (Compound II)1.00µMTTBK11028
Amgen TBK 1 inhibitor (Compound II)1.00µMDYRK1A121
Amgen TBK 1 inhibitor (Compound II)1.00µMDYRK2162
Amgen TBK 1 inhibitor (Compound II)1.00µMDYRK3102
Amgen TBK 1 inhibitor (Compound II)1.00µMNEK2a31
Amgen TBK 1 inhibitor (Compound II)1.00µMNEK6595
Amgen TBK 1 inhibitor (Compound II)1.00µMIKK beta 556
Amgen TBK 1 inhibitor (Compound II)1.00µMIKK epsilon 184
Amgen TBK 1 inhibitor (Compound II)1.00µMTBK181
Amgen TBK 1 inhibitor (Compound II)1.00µMPIM1620
Amgen TBK 1 inhibitor (Compound II)1.00µMPIM21066
Amgen TBK 1 inhibitor (Compound II)1.00µMPIM3634
Amgen TBK 1 inhibitor (Compound II)1.00µMSRPK1871
Amgen TBK 1 inhibitor (Compound II)1.00µMEF2K915
Amgen TBK 1 inhibitor (Compound II)1.00µMEIF2AK3310
Amgen TBK 1 inhibitor (Compound II)1.00µMHIPK1174
Amgen TBK 1 inhibitor (Compound II)1.00µMHIPK2101
Amgen TBK 1 inhibitor (Compound II)1.00µMHIPK3190
Amgen TBK 1 inhibitor (Compound II)1.00µMCLK2114
Amgen TBK 1 inhibitor (Compound II)1.00µMPAK2141
Amgen TBK 1 inhibitor (Compound II)1.00µMPAK490
Amgen TBK 1 inhibitor (Compound II)1.00µMPAK5180
Amgen TBK 1 inhibitor (Compound II)1.00µMPAK6242
Amgen TBK 1 inhibitor (Compound II)1.00µMMST26139
Amgen TBK 1 inhibitor (Compound II)1.00µMMST4672
Amgen TBK 1 inhibitor (Compound II)1.00µMGCK5622
Amgen TBK 1 inhibitor (Compound II)1.00µMMINK1575
Amgen TBK 1 inhibitor (Compound II)1.00µMMEKK1929
Amgen TBK 1 inhibitor (Compound II)1.00µMMLK160
Amgen TBK 1 inhibitor (Compound II)1.00µMMLK380
Amgen TBK 1 inhibitor (Compound II)1.00µMTESK1245
Amgen TBK 1 inhibitor (Compound II)1.00µMTAO1748
Amgen TBK 1 inhibitor (Compound II)1.00µMASK1775
Amgen TBK 1 inhibitor (Compound II)1.00µMTAK11912
Amgen TBK 1 inhibitor (Compound II)1.00µMIRAK152
Amgen TBK 1 inhibitor (Compound II)1.00µMIRAK4201
Amgen TBK 1 inhibitor (Compound II)1.00µMRIPK2141
Amgen TBK 1 inhibitor (Compound II)1.00µMOSR1714
Amgen TBK 1 inhibitor (Compound II)1.00µMTTK644
Amgen TBK 1 inhibitor (Compound II)1.00µMMPSK1425
Amgen TBK 1 inhibitor (Compound II)1.00µMSrc30
Amgen TBK 1 inhibitor (Compound II)1.00µMLck40
Amgen TBK 1 inhibitor (Compound II)1.00µMCSK3815
Amgen TBK 1 inhibitor (Compound II)1.00µMYES172
Amgen TBK 1 inhibitor (Compound II)1.00µMABL73
Amgen TBK 1 inhibitor (Compound II)1.00µMBTK141
Amgen TBK 1 inhibitor (Compound II)1.00µMJAK231
Amgen TBK 1 inhibitor (Compound II)1.00µMSYK130
Amgen TBK 1 inhibitor (Compound II)1.00µMZAP70224
Amgen TBK 1 inhibitor (Compound II)1.00µMTIE2114
Amgen TBK 1 inhibitor (Compound II)1.00µMBRK61
Amgen TBK 1 inhibitor (Compound II)1.00µMEPH-A23226
Amgen TBK 1 inhibitor (Compound II)1.00µMEPH-A451
Amgen TBK 1 inhibitor (Compound II)1.00µMEPH-B131
Amgen TBK 1 inhibitor (Compound II)1.00µMEPH-B262
Amgen TBK 1 inhibitor (Compound II)1.00µMEPH-B3164
Amgen TBK 1 inhibitor (Compound II)1.00µMEPH-B430
Amgen TBK 1 inhibitor (Compound II)1.00µMFGF-R184
Amgen TBK 1 inhibitor (Compound II)1.00µMHER4171
Amgen TBK 1 inhibitor (Compound II)1.00µMIGF-1R61
Amgen TBK 1 inhibitor (Compound II)1.00µMIR217
Amgen TBK 1 inhibitor (Compound II)1.00µMIRR353
Amgen TBK 1 inhibitor (Compound II)1.00µMTrkA111
Amgen TBK 1 inhibitor (Compound II)1.00µMVEGFR120