Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
AZD8055 C25H31N5O4 465.5 mTOR C1, mTOR C2 Chresta C.M. (2010) Cancer Res. 70 288-298 Sini P. (2010) Autophagy 6(4) Selleck Download

Results as Barchart

View results as a bar chart
1µM
0.1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
MARK3 53 72
VEGFR1 76 5
PKB beta 80 10
SRPK1 81 7
DYRK1A 83 14
BTK 83 10
RSK2 84 7
CAMK1 84 5
JNK2 84 3
EPH-B3 85 5
PAK6 86 7
PAK5 87 1
GSK3 beta 87 12
p38 alpha MAPK 87 0
RSK1 88 16
Lck 88 6
CHK2 88 7
PKC zeta 88 2
ERK1 89 21
PKA 89 8
p38 beta MAPK 89 11
p38 delta MAPK 89 20
CAMKK beta 90 5
PRAK 91 16
IKK beta 91 12
PRK2 91 15
MSK1 91 7
SmMLCK 92 10
EPH-A2 92 11
ERK2 92 17
PKB alpha 93 8
IR 94 21
PHK 94 15
IRR 94 12
BRSK2 94 16
PIM3 95 9
YES1 95 4
CK1 delta 96 6
MAPKAP-K2 96 3
PDK1 98 10
PIM2 98 10
DYRK3 99 9
PIM1 99 4
SYK 99 9
JNK1 99 6
PLK1 99 2
MELK 99 27
NEK2a 100 7
AMPK 100 10
EF2K 100 25
CSK 101 14
CHK1 101 15
MST4 101 10
PKC alpha 101 5
ERK8 102 14
MNK2 102 3
CDK2-Cyclin A 102 7
MNK1 102 14
DYRK2 103 15
MKK1 104 6
Src 105 13
S6K1 105 13
p38 gamma MAPK 105 0
HIPK2 105 13
MST2 106 10
IKK epsilon 107 0
IGF-1R 107 2
PAK4 108 17
SGK1 110 10
CK2 113 2
TBK1 116 9
FGF-R1 122 2
PKD1 124 3
ROCK 2 128 31
NEK6 130 41
Screening Concentration: 0.1µM
Kinase % Activity Remainingsort descending Standard Deviation
CAMK1 76 0
ERK2 80 1
p38 alpha MAPK 80 2
VEGFR1 80 7
PAK6 80 1
PKA 81 3
RSK2 81 3
JNK2 82 8
Lck 82 4
IR 83 9
PKB beta 84 10
SRPK1 84 9
DYRK1A 84 11
NEK6 86 13
MNK2 86 4
MST4 87 9
BRSK2 87 15
BTK 89 1
EPH-B3 89 14
CHK1 90 3
RSK1 90 4
ERK1 91 11
EF2K 91 16
MSK1 91 14
MELK 91 18
DYRK3 91 5
IRR 92 1
CK1 delta 92 11
SmMLCK 93 2
PHK 93 6
IKK beta 93 1
EPH-A2 93 2
PRAK 93 0
CSK 93 5
GSK3 beta 94 13
JNK1 94 5
p38 gamma MAPK 94 15
p38 delta MAPK 94 15
PAK5 94 10
PKB alpha 94 3
PKC zeta 95 4
NEK2a 96 11
SYK 96 2
PIM3 97 4
PKC alpha 97 2
PLK1 98 12
AMPK 98 4
MST2 98 2
MAPKAP-K2 98 6
PDK1 98 7
CAMKK beta 98 13
PIM1 99 16
CDK2-Cyclin A 100 1
CHK2 102 12
PRK2 102 11
Src 102 8
PIM2 103 13
TBK1 104 8
MARK3 104 6
YES1 105 5
S6K1 106 6
ROCK 2 106 5
p38 beta MAPK 106 5
DYRK2 107 2
PAK4 108 9
PKD1 111 7
ERK8 111 7
MKK1 112 16
CK2 112 12
SGK1 118 13
IKK epsilon 118 0
HIPK2 118 9
FGF-R1 129 4
IGF-1R 131 3
MNK1 132 20

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