Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
AZD8055 C25H31N5O4 465.5 mTOR C1, mTOR C2 Chresta C.M. (2010) Cancer Res. 70 288-298 Sini P. (2010) Autophagy 6(4) Selleck Download

Results as Barchart

View results as a bar chart
1µM
0.1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 104 6
ERK1 89 21
ERK2 92 17
JNK1 99 6
JNK2 84 3
p38 alpha MAPK 87 0
p38 beta MAPK 89 11
p38 gamma MAPK 105 0
p38 delta MAPK 89 20
ERK8 102 14
RSK1 88 16
RSK2 84 7
PDK1 98 10
PKB alpha 93 8
PKB beta 80 10
SGK1 110 10
S6K1 105 13
PKA 89 8
ROCK 2 128 31
PRK2 91 15
PKC alpha 101 5
PKC zeta 88 2
PKD1 124 3
MSK1 91 7
MNK1 102 14
MNK2 102 3
MAPKAP-K2 96 3
PRAK 91 16
CAMKK beta 90 5
CAMK1 84 5
SmMLCK 92 10
PHK 94 15
CHK1 101 15
CHK2 88 7
GSK3 beta 87 12
CDK2-Cyclin A 102 7
PLK1 99 2
AMPK 100 10
MARK3 53 72
BRSK2 94 16
MELK 99 27
CK1 delta 96 6
CK2 113 2
DYRK1A 83 14
DYRK2 103 15
DYRK3 99 9
NEK2a 100 7
NEK6 130 41
IKK beta 91 12
IKK epsilon 107 0
TBK1 116 9
PIM1 99 4
PIM2 98 10
PIM3 95 9
SRPK1 81 7
EF2K 100 25
HIPK2 105 13
PAK4 108 17
PAK5 87 1
PAK6 86 7
MST2 106 10
MST4 101 10
Src 105 13
Lck 88 6
CSK 101 14
YES1 95 4
BTK 83 10
SYK 99 9
EPH-A2 92 11
EPH-B3 85 5
FGF-R1 122 2
IGF-1R 107 2
IR 94 21
IRR 94 12
VEGFR1 76 5
Screening Concentration: 0.1µM
Kinase % Activity Remaining Standard Deviation
MKK1 112 16
ERK1 91 11
ERK2 80 1
JNK1 94 5
JNK2 82 8
p38 alpha MAPK 80 2
p38 beta MAPK 106 5
p38 gamma MAPK 94 15
p38 delta MAPK 94 15
ERK8 111 7
RSK1 90 4
RSK2 81 3
PDK1 98 7
PKB alpha 94 3
PKB beta 84 10
SGK1 118 13
S6K1 106 6
PKA 81 3
ROCK 2 106 5
PRK2 102 11
PKC alpha 97 2
PKC zeta 95 4
PKD1 111 7
MSK1 91 14
MNK1 132 20
MNK2 86 4
MAPKAP-K2 98 6
PRAK 93 0
CAMKK beta 98 13
CAMK1 76 0
SmMLCK 93 2
PHK 93 6
CHK1 90 3
CHK2 102 12
GSK3 beta 94 13
CDK2-Cyclin A 100 1
PLK1 98 12
AMPK 98 4
MARK3 104 6
BRSK2 87 15
MELK 91 18
CK1 delta 92 11
CK2 112 12
DYRK1A 84 11
DYRK2 107 2
DYRK3 91 5
NEK2a 96 11
NEK6 86 13
IKK beta 93 1
IKK epsilon 118 0
TBK1 104 8
PIM1 99 16
PIM2 103 13
PIM3 97 4
SRPK1 84 9
EF2K 91 16
HIPK2 118 9
PAK4 108 9
PAK5 94 10
PAK6 80 1
MST2 98 2
MST4 87 9
Src 102 8
Lck 82 4
CSK 93 5
YES1 105 5
BTK 89 1
SYK 96 2
EPH-A2 93 2
EPH-B3 89 14
FGF-R1 129 4
IGF-1R 131 3
IR 83 9
IRR 92 1
VEGFR1 80 7

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