Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Staurosporine C28H26N4O3 466.54 Broad spectrum Boix J. (1997) Neuropharmacology 36 811-821 Wiesner D.A. and Dawson G. (1996) J. Neurochem. 66 1418-1425 LC labs Download

Results as Barchart

View results as a bar chart
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 15 15
MKK2 8 3
MKK6 37 0
ERK1 33 8
ERK2 22 1
JNK1 6 0
JNK2 21 1
JNK3 15 2
p38 alpha MAPK 72 0
p38 beta MAPK 60 4
p38 gamma MAPK 13 6
p38 delta MAPK 6 2
ERK8 17 5
RSK1 3 1
RSK2 -1 0
PDK1 18 7
PKB alpha 2 1
PKB beta 0 0
SGK1 1 2
S6K1 4 2
PKA 2 0
ROCK 2 24 9
PRK2 7 1
PKC alpha 4 1
PKC gamma 7 0
PKC zeta 3 1
PKD1 5 0
STK33 6 0
MSK1 1 0
MNK1 38 5
MNK2 39 0
MAPKAP-K2 1 0
MAPKAP-K3 33 7
PRAK 2 1
CAMKK beta 4 1
CAMK1 4 2
SmMLCK 9 3
PHK 26 6
DAPK1 7 0
CHK1 16 11
CHK2 3 0
GSK3 beta 1 1
CDK2-Cyclin A 5 2
PLK1 28 1
Aurora A 1 0
Aurora B 41 3
TLK1 5 3
LKB1 11 0
AMPK 22 3
MARK1 23 1
MARK2 38 11
MARK3 1 2
MARK4 8 0
BRSK1 8 2
BRSK2 2 1
MELK 20 1
NUAK1 4 1
CK1 delta 63 11
CK2 69 10
DYRK1A 0 0
DYRK2 13 4
DYRK3 6 2
NEK2a 11 1
NEK6 69 4
IKK beta 11 1
IKK epsilon 14 7
TBK1 5 2
PIM1 8 2
PIM2 3 1
PIM3 7 11
SRPK1 2 0
EF2K 112 2
EIF2AK3 18 3
HIPK1 26 5
HIPK2 5 3
HIPK3 13 2
CLK2 2 0
PAK2 1 0
PAK4 8 7
PAK5 3 1
PAK6 0 0
MST2 30 9
MST4 29 6
GCK 7 2
MINK1 19 0
MEKK1 33 8
MLK1 24 9
MLK3 14 4
TAO1 4 1
ASK1 8 0
TAK1 2 1
IRAK1 2 0
IRAK4 3 1
RIPK2 21 2
OSR1 2 1
TTK 23 6
MPSK1 16 0
Src 3 1
Lck 6 0
CSK 36 9
YES1 8 4
ABL 3 1
BTK 16 1
JAK2 5 0
SYK 4 1
ZAP70 6 0
TIE2 9 4
BRK 7 4
EPH-A2 11 3
EPH-A4 16 0
EPH-B1 118 11
EPH-B2 3 0
EPH-B3 7 0
EPH-B4 12 2
FGF-R1 3 0
HER4 10 2
IGF-1R 1 0
IR 1 1
IRR 4 0
TrkA 1 0
VEGFR1 2 0

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