Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Ubiquitin E1 Inhibitor (PYR-41) C17H13N3O7 • 3H2O 425.4 Ubiquitin-E1 Yang Y (2007) Cancer Res. 67 9472 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 29 4
MKK2 9 1
MKK6 87 3
ERK1 103 14
ERK2 82 7
JNK1 117 8
JNK2 93 5
JNK3 79 13
p38 alpha MAPK 105 11
p38 beta MAPK 113 4
p38 gamma MAPK 112 8
p38 delta MAPK 106 10
ERK8 86 3
RSK1 92 7
RSK2 37 5
PDK1 82 0
PKB alpha 79 15
PKB beta 49 17
SGK1 126 15
S6K1 120 18
PKA 95 6
ROCK 2 91 3
PRK2 105 0
PKC alpha 96 9
PKC gamma 99 18
PKC zeta 112 4
PKD1 61 1
STK33 119 14
MSK1 62 12
MNK1 110 3
MNK2 89 11
MAPKAP-K2 78 1
MAPKAP-K3 41 1
PRAK 97 9
CAMKK beta 125 2
CAMK1 102 7
SmMLCK 109 1
PHK 68 21
DAPK1 112 4
CHK1 164 12
CHK2 92 3
GSK3 beta 106 3
CDK2-Cyclin A 110 14
PLK1 92 18
Aurora A 76 2
Aurora B 102 17
TLK1 108 3
LKB1 134 3
AMPK 108 5
MARK1 62 6
MARK2 116 30
MARK3 84 0
MARK4 52 11
BRSK1 86 12
BRSK2 42 17
MELK 82 3
NUAK1 75 24
CK1 delta 112 6
CK2 106 3
DYRK1A 70 6
DYRK2 54 8
DYRK3 55 2
NEK2a 125 17
NEK6 106 0
IKK beta 108 14
IKK epsilon 156 3
TBK1 100 10
PIM1 109 2
PIM2 107 1
PIM3 92 5
SRPK1 76 1
EF2K 97 1
EIF2AK3 83 11
HIPK1 98 12
HIPK2 81 20
HIPK3 103 14
CLK2 126 1
PAK2 91 8
PAK4 55 9
PAK5 118 9
PAK6 133 5
MST2 122 5
MST4 87 9
GCK 96 6
MINK1 73 5
MEKK1 81 41
MLK1 78 0
MLK3 100 2
TAO1 126 2
ASK1 115 28
TAK1 102 6
IRAK1 84 4
IRAK4 112 11
RIPK2 134 3
OSR1 115 7
TTK 90 12
MPSK1 87 25
Src 79 29
Lck 121 9
CSK 134 26
YES1 110 9
ABL 107 7
BTK 70 7
JAK2 17 0
SYK 92 9
ZAP70 95 2
TIE2 128 9
BRK 79 5
EPH-A2 90 16
EPH-A4 75 7
EPH-B1 85 19
EPH-B2 81 4
EPH-B3 100 9
EPH-B4 89 1
FGF-R1 69 3
HER4 91 1
IGF-1R 116 35
IR 99 5
IRR 106 6
TrkA 104 0
VEGFR1 47 4

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