Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Sodium salicylate HOC6H4COONa 160.10 p38 Schwenger P. (1998) Mol Cell Biol. Jan 18(1) 78-84 Sigma Download

Results as Barchart

View results as a bar chart
10µM
1µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 48 16
MKK2 88 0
MKK6 143 4
ERK1 99 20
ERK2 89 0
JNK1 136 2
JNK2 109 1
JNK3 100 8
p38 alpha MAPK 95 6
p38 beta MAPK 101 24
p38 gamma MAPK 36 0
p38 delta MAPK 73 1
ERK8 36 6
RSK1 89 19
RSK2 56 11
PDK1 86 7
PKB alpha 66 4
PKB beta 40 2
SGK1 69 4
S6K1 59 3
PKA 101 25
ROCK 2 86 7
PRK2 77 6
PKC alpha 92 4
PKC gamma 68 5
PKC zeta 110 2
PKD1 69 10
STK33 80 9
MSK1 57 2
MNK1 44 3
MNK2 68 4
MAPKAP-K2 97 16
MAPKAP-K3 55 1
PRAK 49 5
CAMKK beta 30 17
CAMK1 56 1
SmMLCK 64 3
PHK 59 8
DAPK1 17 1
CHK1 130 2
CHK2 36 6
GSK3 beta 48 2
CDK2-Cyclin A 89 9
PLK1 108 7
Aurora A 18 3
Aurora B 89 34
TLK1 131 24
LKB1 64 4
AMPK 88 4
MARK1 51 10
MARK2 75 3
MARK3 71 9
MARK4 65 8
BRSK1 70 3
BRSK2 50 7
MELK 123 4
NUAK1 50 0
CK1 delta 35 5
CK2 5 2
DYRK1A 40 10
DYRK2 37 4
DYRK3 30 3
NEK2a 64 4
NEK6 69 3
IKK beta 93 25
IKK epsilon 111 2
TBK1 60 6
PIM1 9 1
PIM2 35 0
PIM3 12 6
SRPK1 12 1
EF2K 52 1
EIF2AK3 44 6
HIPK1 59 4
HIPK2 39 11
HIPK3 93 10
CLK2 79 18
PAK2 64 14
PAK4 38 5
PAK5 55 3
PAK6 47 6
MST2 90 18
MST4 82 8
GCK 64 11
MINK1 107 16
MEKK1 147 13
MLK1 50 6
MLK3 103 11
TAO1 66 4
ASK1 107 12
TAK1 143 20
IRAK1 43 4
IRAK4 61 5
RIPK2 57 11
OSR1 55 18
TTK 49 15
MPSK1 98 6
Src 50 2
Lck 81 19
CSK 62 5
YES1 59 27
ABL 95 5
BTK 19 3
JAK2 47 5
SYK 48 2
ZAP70 124 2
TIE2 93 0
BRK 64 15
EPH-A2 66 3
EPH-A4 89 7
EPH-B1 85 13
EPH-B2 58 3
EPH-B3 57 18
EPH-B4 142 9
FGF-R1 25 6
HER4 33 2
IGF-1R 67 7
IR 38 6
IRR 68 23
TrkA 42 6
VEGFR1 19 0
Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 81 2
MKK2 77 6
MKK6 113 6
ERK1 88 15
ERK2 82 1
JNK1 102 4
JNK2 103 2
JNK3 82 31
p38 alpha MAPK 100 22
p38 beta MAPK 91 5
p38 gamma MAPK 82 2
p38 delta MAPK 94 12
ERK8 69 0
RSK1 93 2
RSK2 86 8
PDK1 88 10
PKB alpha 97 4
PKB beta 75 3
SGK1 82 2
S6K1 95 5
PKA 94 3
ROCK 2 95 5
PRK2 93 12
PKC alpha 101 0
PKC gamma 95 16
PKC zeta 84 6
PKD1 97 3
STK33 95 5
MSK1 91 1
MNK1 83 5
MNK2 95 5
MAPKAP-K2 101 16
MAPKAP-K3 71 3
PRAK 87 6
CAMKK beta 75 3
CAMK1 79 1
SmMLCK 96 6
PHK 82 5
DAPK1 47 5
CHK1 102 5
CHK2 81 5
GSK3 beta 91 3
CDK2-Cyclin A 102 18
PLK1 107 10
Aurora A 77 1
Aurora B 75 11
TLK1 102 1
LKB1 81 1
AMPK 102 18
MARK1 83 1
MARK2 86 12
MARK3 85 4
MARK4 89 0
BRSK1 86 23
BRSK2 86 4
MELK 94 9
NUAK1 85 2
CK1 delta 92 13
CK2 11 1
DYRK1A 47 6
DYRK2 87 14
DYRK3 75 7
NEK2a 94 5
NEK6 89 7
IKK beta 88 1
IKK epsilon 109 4
TBK1 85 5
PIM1 35 2
PIM2 67 1
PIM3 13 5
SRPK1 61 1
EF2K 91 0
EIF2AK3 89 15
HIPK1 87 4
HIPK2 69 1
HIPK3 112 8
CLK2 84 11
PAK2 87 2
PAK4 73 8
PAK5 80 7
PAK6 84 8
MST2 99 7
MST4 87 13
GCK 81 3
MINK1 103 1
MEKK1 102 18
MLK1 76 7
MLK3 118 22
TAO1 86 9
ASK1 93 2
TAK1 137 23
IRAK1 89 6
IRAK4 92 5
RIPK2 73 4
OSR1 85 10
TTK 82 8
MPSK1 98 16
Src 81 2
Lck 105 3
CSK 109 8
YES1 79 1
ABL 88 10
BTK 74 8
JAK2 101 16
SYK 80 25
ZAP70 103 11
TIE2 97 2
BRK 91 9
EPH-A2 99 4
EPH-A4 97 13
EPH-B1 96 1
EPH-B2 92 0
EPH-B3 83 7
EPH-B4 114 13
FGF-R1 85 20
HER4 83 1
IGF-1R 91 1
IR 91 13
IRR 84 3
TrkA 82 14
VEGFR1 65 3

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