Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
LRRK2-IN1 C31H38N8O3 570.69 LRRK2 Deng X. (2011) Nat. Chem. Biol. 7 203 WO2010080712 Download

Results as Barchart

View results as a bar chart
10µM
1µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
Aurora A 5 0
CHK2 9 3
BRK 17 4
STK33 26 0
CAMKK beta 29 8
p38 beta MAPK 30 1
NUAK1 31 4
Aurora B 31 5
OSR1 32 5
SmMLCK 35 6
MNK2 44 6
PKD1 50 1
FGF-R1 52 12
CAMK1 53 5
MNK1 53 0
PHK 54 6
PLK1 58 11
PIM3 60 5
IR 65 11
YES1 67 7
CHK1 67 6
AMPK 67 8
GCK 70 11
TAO1 70 6
HIPK2 70 8
TAK1 72 13
CLK2 72 10
JNK3 73 3
TTK 73 6
S6K1 74 3
MLK1 75 8
p38 gamma MAPK 76 4
DAPK1 77 5
LKB1 77 4
IRR 78 9
BTK 79 1
MAPKAP-K3 79 6
MKK2 79 13
JAK2 80 8
MST2 80 3
JNK1 81 6
RIPK2 81 5
MKK1 81 3
MARK3 82 6
PIM1 82 8
EPH-A2 82 12
IKK beta 82 4
PAK5 83 10
MARK2 83 1
MST4 83 5
ASK1 84 4
CK2 84 12
TLK1 84 3
ERK2 85 1
ROCK 2 85 11
ABL 85 3
p38 alpha MAPK 85 2
SYK 85 13
SGK1 85 5
Lck 85 12
IGF-1R 86 7
PRK2 86 9
GSK3 beta 86 1
RSK2 86 5
JNK2 87 8
BRSK2 87 9
CK1 delta 87 8
CDK2-Cyclin A 88 2
PAK6 88 6
MARK4 89 9
TrkA 89 15
VEGFR1 89 9
MSK1 89 8
PAK2 89 2
HIPK1 90 15
IRAK4 90 2
MAPKAP-K2 90 12
NEK6 90 1
PKB beta 90 9
HER4 91 6
DYRK1A 91 7
DYRK3 91 6
EPH-B3 91 8
MARK1 91 8
MKK6 91 3
BRSK1 92 2
MELK 92 4
EIF2AK3 92 10
ERK8 92 8
PKA 93 3
RSK1 93 9
PRAK 93 2
SRPK1 94 2
NEK2a 95 3
PIM2 97 5
IRAK1 97 4
MEKK1 98 3
HIPK3 98 14
PAK4 98 9
PDK1 98 0
CSK 99 2
PKC alpha 99 7
DYRK2 99 9
PKB alpha 99 2
ERK1 101 5
EF2K 102 8
TIE2 104 0
EPH-B1 104 4
MPSK1 104 7
TBK1 105 1
IKK epsilon 106 14
p38 delta MAPK 107 6
MINK1 108 7
MLK3 110 13
ZAP70 110 8
PKC zeta 112 14
EPH-B2 113 4
Src 116 3
PKC gamma 118 13
EPH-B4 118 0
EPH-A4 121 4
Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
Aurora A 30 0
CHK2 39 10
Aurora B 56 1
BRK 60 12
CAMKK beta 61 12
p38 beta MAPK 62 4
PIM3 63 5
STK33 67 0
MLK1 69 1
AMPK 70 7
CK2 71 6
SYK 71 5
MNK1 72 1
PKD1 73 7
TAK1 74 2
HIPK2 76 2
OSR1 76 3
MARK3 76 6
SmMLCK 76 8
MKK1 77 3
MKK2 77 13
PKA 77 7
NUAK1 77 2
DYRK1A 78 8
VEGFR1 78 10
MST4 79 1
GCK 81 2
ERK2 82 14
ROCK 2 82 14
PRK2 82 0
CHK1 82 9
FGF-R1 83 4
BRSK1 83 6
TrkA 83 7
RSK2 84 4
p38 gamma MAPK 85 9
IRAK4 85 2
MARK2 85 3
MAPKAP-K2 86 1
MAPKAP-K3 86 4
IKK beta 86 5
S6K1 86 9
GSK3 beta 86 9
CDK2-Cyclin A 87 3
LKB1 87 8
TTK 87 6
IGF-1R 87 6
BTK 87 1
IRR 87 11
p38 alpha MAPK 87 10
PAK2 88 3
IR 88 6
MSK1 89 5
CLK2 89 7
RSK1 89 3
PIM2 89 3
ABL 89 3
HIPK1 89 1
ASK1 89 4
DYRK3 90 8
TLK1 90 6
MPSK1 90 1
MST2 90 3
EPH-B1 91 0
PDK1 91 10
PAK6 91 3
JNK2 91 2
PKC alpha 91 8
EIF2AK3 91 9
CK1 delta 91 2
TAO1 92 8
NEK2a 93 12
EPH-B2 93 8
EPH-B3 93 14
SGK1 93 2
PHK 93 5
MNK2 94 3
TBK1 94 6
CAMK1 95 5
PAK5 96 1
YES1 96 6
IRAK1 97 9
MKK6 98 2
SRPK1 98 4
NEK6 99 3
MARK1 99 1
Src 99 4
EPH-B4 99 5
MINK1 99 8
JAK2 99 10
MELK 100 8
PKB alpha 101 10
PKB beta 101 13
IKK epsilon 101 1
PIM1 101 15
HER4 102 2
JNK1 102 10
BRSK2 102 3
PKC zeta 102 5
RIPK2 103 4
PRAK 103 1
p38 delta MAPK 104 7
EPH-A2 104 3
CSK 104 6
DAPK1 104 5
JNK3 104 14
ERK1 105 0
MARK4 105 7
TIE2 106 9
DYRK2 106 11
Lck 106 13
PAK4 107 1
EF2K 107 1
MLK3 108 5
PLK1 109 12
ERK8 111 7
EPH-A4 114 13
ZAP70 114 3
MEKK1 122 9
HIPK3 123 8
PKC gamma 124 2

Do you need any help? Please get in touch and we’ll be happy to lend a hand.