Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
AX 20017 C13H16N2O2S 264.34 PknG Walburger A (2004) Science 304 1800-1804 Merck Millipore Download

Results as Barchart

View results as a bar chart
10µM
1µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
VEGFR1 9 0
GCK 17 2
Aurora A 22 3
IRAK4 28 2
TrkA 30 3
NUAK1 30 2
MLK1 32 9
CHK2 35 4
RIPK2 36 1
MINK1 37 7
MLK3 37 1
GSK3 beta 42 2
MELK 44 5
FGF-R1 46 14
PAK4 46 4
CDK2-Cyclin A 48 1
DYRK1A 48 2
CAMKK beta 48 4
CLK2 49 13
SmMLCK 49 4
HIPK2 52 2
EPH-A2 52 6
IRR 52 4
MST2 53 3
TAK1 53 8
EPH-A4 53 6
PAK5 54 10
EPH-B4 55 3
MST4 57 3
JAK2 60 5
Aurora B 62 16
PRAK 62 9
PHK 62 1
EPH-B2 62 7
ERK8 67 5
MARK1 67 4
BTK 68 1
PIM3 68 9
TAO1 69 11
MARK3 69 5
MARK4 69 12
CAMK1 70 5
BRSK2 73 8
STK33 74 10
MKK2 74 10
TIE2 75 18
EPH-B1 76 39
Lck 77 6
MNK1 77 3
YES1 79 13
IGF-1R 79 1
PAK6 80 14
ZAP70 80 8
TTK 80 13
CK1 delta 81 10
LKB1 81 11
ABL 82 11
JNK3 84 1
CHK1 84 1
DYRK2 86 2
AMPK 86 12
DAPK1 86 12
PKC alpha 86 9
HIPK1 87 7
PIM1 87 2
Src 87 2
CSK 88 5
MKK1 88 5
RSK2 89 1
ERK2 89 14
EF2K 90 12
PKD1 90 9
BRSK1 90 1
MAPKAP-K2 91 22
ROCK 2 91 3
NEK2a 92 2
PIM2 92 0
MPSK1 92 3
SRPK1 93 6
MAPKAP-K3 93 6
NEK6 93 3
IKK beta 93 5
p38 gamma MAPK 94 12
RSK1 95 1
BRK 95 7
PAK2 96 14
PKB beta 96 0
ASK1 96 4
JNK2 96 2
p38 delta MAPK 97 9
IR 97 0
PRK2 97 13
p38 beta MAPK 98 1
HER4 98 2
S6K1 98 6
MKK6 99 1
PLK1 100 4
p38 alpha MAPK 101 16
HIPK3 102 10
PDK1 102 11
PKB alpha 102 10
PKA 102 15
JNK1 102 10
PKC zeta 104 11
CK2 106 11
SYK 106 9
SGK1 107 5
TBK1 107 2
MSK1 108 11
DYRK3 109 11
IKK epsilon 109 11
EPH-B3 109 6
PKC gamma 110 5
MNK2 115 13
MARK2 124 73
ERK1 125 16
MEKK1 132 51
Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
VEGFR1 45 3
IRAK4 68 5
GCK 69 2
MELK 71 16
MLK1 72 11
CHK2 74 7
NUAK1 75 0
Aurora B 79 4
MINK1 80 7
PAK6 83 8
DYRK1A 85 4
RIPK2 86 16
PKD1 86 11
IGF-1R 86 1
Aurora A 87 6
TAO1 87 0
EPH-A2 87 9
STK33 87 4
MLK3 89 1
HIPK3 89 6
CLK2 89 5
CDK2-Cyclin A 89 3
TrkA 90 2
GSK3 beta 90 8
MST2 90 16
MARK3 90 3
BTK 90 2
LKB1 91 7
TAK1 92 17
PAK2 92 1
YES1 92 7
MKK1 92 2
PKC alpha 93 0
p38 gamma MAPK 93 5
PAK4 93 2
MARK1 93 9
ABL 93 1
MKK2 93 3
ZAP70 94 8
JNK3 94 3
HIPK2 94 9
CK2 94 22
ROCK 2 95 4
CHK1 95 3
SmMLCK 96 5
CK1 delta 96 10
CSK 96 2
PRAK 96 4
PIM1 96 4
BRSK1 97 3
SRPK1 97 7
JNK1 97 3
EF2K 97 9
MNK1 97 9
MARK2 97 5
IRR 97 5
PIM2 98 1
CAMK1 98 3
PKC gamma 98 7
PLK1 98 9
Lck 98 13
MAPKAP-K2 98 15
ERK2 99 1
BRSK2 99 6
p38 beta MAPK 99 10
NEK2a 99 1
TBK1 99 15
S6K1 100 3
PKA 100 1
TIE2 100 22
HIPK1 100 16
p38 alpha MAPK 100 10
TTK 100 17
PAK5 100 10
IKK beta 100 4
MST4 100 1
MAPKAP-K3 100 2
PKB beta 100 2
EPH-B4 101 1
RSK1 101 9
IR 101 8
SYK 102 7
DAPK1 102 2
Src 102 0
AMPK 103 11
JAK2 104 6
PKC zeta 104 0
EPH-B2 104 12
MARK4 105 0
FGF-R1 105 6
CAMKK beta 106 7
JNK2 106 5
PRK2 106 0
ASK1 106 8
ERK8 106 1
MNK2 106 4
HER4 106 4
ERK1 107 15
MPSK1 107 3
NEK6 107 14
RSK2 107 16
PHK 108 13
MSK1 108 1
MKK6 109 2
SGK1 109 5
DYRK2 109 2
PIM3 111 9
DYRK3 111 9
PDK1 111 14
BRK 114 1
EPH-A4 114 13
EPH-B3 115 5
PKB alpha 115 7
p38 delta MAPK 116 4
EPH-B1 117 14
MEKK1 124 42
IKK epsilon 211 147

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