Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
MLN9708 C20H23BCl2N2O9 517.12 Proteasome Kupperman. E. (2010) Cancer Research 70 1970-1980 Selleck Download

Results as Barchart

View results as a bar chart
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 92 9
MKK2 94 6
MKK6 92 6
ERK1 106 5
ERK2 86 0
JNK1 85 1
JNK2 87 8
JNK3 91 3
p38 alpha MAPK 88 1
p38 beta MAPK 70 2
p38 gamma MAPK 104 25
p38 delta MAPK 98 6
ERK8 100 5
RSK1 80 8
RSK2 94 2
PDK1 80 2
PKB alpha 83 1
PKB beta 82 1
SGK1 78 11
S6K1 94 9
PKA 95 12
ROCK 2 76 0
PRK2 86 2
PKC alpha 113 11
PKC gamma 114 5
PKC zeta 95 4
PKD1 82 0
STK33 98 13
MSK1 97 22
MNK1 79 2
MNK2 80 14
MAPKAP-K2 88 2
MAPKAP-K3 102 0
PRAK 92 9
CAMKK beta 86 4
CAMK1 80 2
SmMLCK 103 9
PHK 44 3
DAPK1 88 12
CHK1 107 2
CHK2 89 9
GSK3 beta 88 9
CDK2-Cyclin A 86 5
PLK1 97 4
Aurora A 105 9
Aurora B 75 3
LKB1 124 7
AMPK 82 2
MARK1 81 9
MARK2 81 5
MARK3 72 18
MARK4 86 2
BRSK1 90 8
BRSK2 90 1
MELK 80 11
NUAK1 78 14
CK1 delta 81 3
CK2 82 2
DYRK1A 88 10
DYRK2 94 11
DYRK3 97 1
NEK2a 94 12
NEK6 82 2
IKK beta 97 9
IKK epsilon 91 6
TBK1 81 1
PIM1 88 4
PIM2 94 12
PIM3 92 11
SRPK1 90 1
EF2K 83 10
HIPK1 111 10
HIPK2 88 7
HIPK3 118 5
CLK2 79 6
PAK2 92 6
PAK4 77 6
PAK5 94 19
PAK6 68 1
MST2 100 3
MST4 122 6
GCK 44 48
MINK1 73 5
MEKK1 92 1
MLK1 75 0
MLK3 99 6
TAO1 113 21
ASK1 81 2
TAK1 127 18
IRAK4 79 3
RIPK2 91 10
TTK 93 10
MPSK1 102 17
Src 86 0
Lck 81 1
CSK 69 10
YES1 82 2
ABL 101 3
BTK 90 11
JAK2 104 13
SYK 66 7
ZAP70 84 11
TIE2 98 0
BRK 96 6
EPH-A2 98 6
EPH-A4 69 7
EPH-B1 75 8
EPH-B2 95 8
EPH-B3 62 16
EPH-B4 91 5
FGF-R1 69 7
HER4 72 6
IGF-1R 87 15
IR 58 3
IRR 104 10
TrkA 95 0
VEGFR1 64 3

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