Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
(5Z)-7-Oxozeaenol C19H22O7 362.37 TAK1 Ninomiya-Tsuji (2003) J.Biol.Chem. 278 18485 Windheim et al (2007) Biochem.J. 404 179 Tocris Download

Results as Barchart

View results as a bar chart
0.1µM
1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
MKK1 2 1
MKK2 3 2
TAK1 3 1
ERK8 4 4
MKK6 10 2
MNK1 13 5
VEGFR1 13 6
PRAK 14 11
TrkA 24 11
BRK 25 0
MNK2 26 1
IRAK4 28 2
Lck 30 4
PKD1 31 11
RIPK2 39 2
Src 43 3
EPH-A4 46 8
JNK1 52 14
EPH-A2 55 2
CSK 56 7
CAMKK beta 57 2
YES1 60 2
ERK1 64 0
LKB1 65 1
ERK2 65 7
TAO1 66 5
RSK2 70 13
ABL 71 6
p38 beta MAPK 72 0
MST4 72 9
PIM1 72 9
GSK3 beta 74 5
Aurora B 74 6
EPH-B2 75 5
JAK2 75 0
MLK1 75 1
PDK1 76 3
CK2 77 1
MARK3 77 14
SYK 77 5
NUAK1 78 3
MAPKAP-K2 79 4
MLK3 79 18
GCK 80 0
SmMLCK 80 5
PIM3 80 3
EPH-B1 81 8
PAK4 81 6
JNK2 81 4
S6K1 82 4
HIPK2 82 4
MINK1 83 1
ROCK 2 83 6
PKB beta 84 10
STK33 85 2
EF2K 85 3
PKC alpha 85 3
p38 alpha MAPK 85 4
MARK4 86 4
PAK6 87 1
FGF-R1 87 7
PKC gamma 87 10
CHK2 87 1
CDK2-Cyclin A 88 3
BRSK2 88 11
SRPK1 88 5
DYRK2 89 5
NEK2a 89 1
MST2 89 4
PHK 89 5
CLK2 90 2
RSK1 90 2
EPH-B4 90 5
BRSK1 90 4
JNK3 90 11
TTK 91 8
PKB alpha 91 1
PRK2 91 15
p38 gamma MAPK 92 6
AMPK 92 5
IKK epsilon 92 10
MEKK1 92 2
CHK1 92 3
NEK6 93 5
IGF-1R 93 8
BTK 93 0
PKA 93 1
TIE2 93 9
MAPKAP-K3 94 5
IR 94 7
DAPK1 94 2
MELK 94 4
IKK beta 95 6
HER4 95 1
SGK1 95 1
ASK1 95 6
IRR 96 14
ZAP70 96 6
DYRK1A 97 1
HIPK1 98 9
PKC zeta 99 12
MARK1 99 0
PLK1 100 6
MSK1 100 1
EPH-B3 100 4
DYRK3 101 2
MPSK1 101 10
TBK1 102 13
HIPK3 103 10
PAK5 103 6
CK1 delta 104 6
Aurora A 105 2
CAMK1 105 11
PIM2 106 4
PAK2 110 8
p38 delta MAPK 114 14
MARK2 114 3
Screening Concentration: 0.1µM
Kinase % Activity Remainingsort descending Standard Deviation
TAK1 5 1
VEGFR1 8 0
MKK2 12 2
MKK6 12 4
MKK1 13 2
ERK8 40 2
MNK2 41 3
TrkA 46 0
EF2K 48 57
MNK1 55 0
BRK 65 13
PRAK 66 7
PKD1 71 6
Lck 78 1
BRSK2 84 11
PKB beta 86 9
CAMKK beta 87 4
PKC gamma 87 4
EPH-B4 87 6
CAMK1 88 2
SYK 88 3
BTK 90 5
JNK1 90 0
p38 beta MAPK 90 9
HIPK3 90 2
PIM2 91 7
ASK1 91 1
EPH-A4 91 4
DYRK3 94 7
PAK4 94 11
Aurora B 94 1
MELK 95 11
CLK2 96 17
EPH-B2 96 21
PAK5 96 9
HIPK2 98 9
PDK1 99 10
PKA 99 7
EPH-A2 99 8
IRAK4 99 4
p38 gamma MAPK 99 1
EPH-B1 99 11
p38 delta MAPK 99 2
PAK6 100 5
AMPK 100 7
HER4 100 2
IGF-1R 100 16
PHK 100 2
MINK1 101 9
IKK beta 102 17
PIM1 102 1
PRK2 102 2
HIPK1 102 11
CK1 delta 102 4
GSK3 beta 102 13
ERK2 103 2
TAO1 103 3
TIE2 103 16
p38 alpha MAPK 103 3
RIPK2 103 5
PLK1 103 1
MPSK1 103 6
SRPK1 104 10
PAK2 104 5
TTK 104 2
FGF-R1 105 24
YES1 105 40
TBK1 105 1
PKC zeta 105 1
RSK2 106 6
SGK1 106 2
ERK1 106 15
CK2 106 15
Aurora A 106 20
Src 106 4
IRR 107 52
MARK4 107 1
MEKK1 107 5
JNK3 107 2
PKC alpha 107 3
MSK1 107 25
ABL 108 5
JAK2 108 11
SmMLCK 108 4
DAPK1 108 1
NEK2a 108 0
MARK2 109 1
MLK1 109 4
JNK2 109 12
IR 110 10
ZAP70 110 4
CHK2 110 1
PKB alpha 111 9
EPH-B3 111 8
MARK1 112 16
S6K1 112 8
MAPKAP-K3 113 18
BRSK1 113 12
NUAK1 113 9
RSK1 113 1
MLK3 114 16
CHK1 114 13
DYRK2 114 5
MARK3 116 11
ROCK 2 116 13
DYRK1A 117 0
CSK 118 16
CDK2-Cyclin A 119 7
MST2 120 14
IKK epsilon 120 4
STK33 120 13
GCK 121 3
NEK6 122 5
MAPKAP-K2 124 4
PIM3 126 6
MST4 129 6
LKB1 138 6

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