Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
BML-258 (SK1-I) C17H28ClNO2 313.86 SphK1 Paugh S.W. (2008) Blood 112 1382-1391 SuperNova Life Science Download

Results as Barchart

View results as a bar chart
0.1µM
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
PRK2 58 1
IRAK4 67 1
EF2K 69 1
GSK3 beta 71 2
GCK 71 9
PHK 76 0
ERK8 77 0
SGK1 78 4
p38 alpha MAPK 80 9
CK1 delta 81 4
RSK1 81 8
RSK2 81 11
CHK2 82 8
CK2 83 2
MARK2 83 6
VEGFR1 83 4
SRPK1 83 9
DYRK1A 84 6
NEK6 84 9
Lck 84 11
PAK4 85 5
ERK1 85 4
TTK 86 4
EPH-B3 86 0
IKK epsilon 86 4
PKB beta 86 2
TrkA 86 0
CHK1 86 9
p38 gamma MAPK 87 5
CDK2-Cyclin A 88 3
JNK2 88 5
STK33 89 16
CAMK1 89 5
MEKK1 89 0
PKC alpha 89 5
p38 delta MAPK 90 1
PRAK 90 3
CAMKK beta 90 2
JNK1 90 21
EPH-A2 91 6
MAPKAP-K2 91 4
SmMLCK 91 15
TAO1 91 6
PKC zeta 92 5
Aurora A 92 15
SYK 92 13
ZAP70 92 0
DYRK3 93 9
MNK1 93 1
Aurora B 93 0
IGF-1R 93 14
TBK1 93 1
MARK4 93 10
AMPK 94 6
MST2 94 7
HIPK1 94 18
ASK1 94 0
p38 beta MAPK 95 2
MSK1 95 1
PIM1 95 10
PKC gamma 96 1
EPH-A4 96 7
PLK1 96 3
CLK2 97 11
MKK1 97 9
PIM2 97 2
BRSK1 97 1
LKB1 98 4
CSK 98 5
MELK 98 14
JNK3 98 8
IR 99 2
MKK6 99 1
RIPK2 100 4
MPSK1 100 4
IKK beta 100 6
IRR 100 5
S6K1 100 0
JAK2 100 10
ERK2 100 5
MLK1 100 3
PAK5 101 4
NUAK1 101 5
HIPK3 102 3
MNK2 102 14
PAK6 103 5
BTK 103 15
DAPK1 103 18
FGF-R1 104 1
MARK1 104 6
BRK 104 2
HER4 105 6
MARK3 105 0
HIPK2 106 5
PKB alpha 107 24
PKA 107 12
PIM3 107 2
EPH-B2 108 5
NEK2a 108 7
MST4 108 13
BRSK2 108 7
YES1 109 2
MKK2 109 19
ABL 109 10
MLK3 109 12
TAK1 111 2
Src 111 13
MINK1 111 13
PAK2 113 8
TIE2 113 4
PKD1 115 15
EPH-B1 115 18
ROCK 2 116 3
DYRK2 119 7
PDK1 122 9
EPH-B4 123 13
MAPKAP-K3 123 7
Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
IRAK4 66 0
PRK2 70 1
GCK 72 2
EF2K 76 0
CDK2-Cyclin A 79 7
p38 gamma MAPK 80 11
CAMKK beta 81 15
VEGFR1 81 5
TBK1 82 39
CHK2 84 4
NEK6 86 12
IGF-1R 86 2
PHK 86 0
ERK8 86 1
SGK1 87 3
p38 alpha MAPK 87 13
CK1 delta 87 7
CK2 87 12
PKC alpha 88 5
GSK3 beta 88 3
LKB1 89 0
MARK4 89 8
SRPK1 89 3
MST2 90 0
PKB beta 90 13
ERK2 90 9
JNK2 90 2
EPH-A2 91 9
DYRK1A 91 6
TTK 91 4
PAK4 91 9
MNK1 92 16
Lck 92 8
CHK1 92 7
MINK1 93 11
BRK 93 8
IRR 94 3
JNK1 94 3
ROCK 2 94 5
PLK1 94 7
RSK2 95 1
MAPKAP-K2 95 6
IKK epsilon 95 6
PIM1 95 11
SmMLCK 95 12
RIPK2 95 3
AMPK 96 0
MST4 96 9
IKK beta 97 7
PKB alpha 97 8
MARK2 97 9
ERK1 97 9
RSK1 98 4
MNK2 98 3
MKK6 98 4
JAK2 98 3
DYRK3 98 1
MPSK1 98 8
PRAK 99 12
MEKK1 99 4
MELK 99 7
ASK1 99 3
p38 delta MAPK 99 5
PAK5 100 8
Src 100 3
YES1 100 9
STK33 100 11
EPH-B3 100 9
EPH-B4 101 8
CSK 101 15
CAMK1 101 11
DAPK1 101 11
EPH-A4 101 8
Aurora B 102 4
MKK1 102 5
NEK2a 103 2
MKK2 103 12
IR 103 20
BTK 103 5
JNK3 103 7
PAK2 103 1
CLK2 104 12
MSK1 104 18
SYK 105 6
EPH-B2 105 10
Aurora A 105 4
PDK1 106 2
ABL 106 11
PKA 106 2
MLK3 106 4
ZAP70 106 10
HIPK2 106 6
p38 beta MAPK 106 2
HER4 107 20
MARK3 107 7
PAK6 108 7
S6K1 108 6
MLK1 108 6
BRSK2 108 1
TAO1 108 9
NUAK1 108 6
TAK1 108 4
PKC zeta 108 3
EPH-B1 108 7
PIM2 109 3
PKC gamma 109 8
TrkA 110 9
FGF-R1 111 12
BRSK1 111 0
MARK1 112 17
HIPK1 112 6
HIPK3 112 2
PKD1 112 4
TIE2 118 3
MAPKAP-K3 119 1
PIM3 121 6
DYRK2 124 3
Screening Concentration: 0.1µM
Kinase % Activity Remainingsort descending Standard Deviation
IRAK4 72 6
PRK2 78 4
CK2 78 12
ERK8 82 1
SGK1 83 5
GSK3 beta 83 8
DYRK1A 83 4
JNK2 85 6
PKB beta 85 2
GCK 86 2
RSK2 87 3
IGF-1R 87 12
CK1 delta 88 9
PRAK 89 2
MARK2 89 5
MARK4 90 11
SmMLCK 90 2
p38 delta MAPK 90 9
PAK4 91 4
IKK beta 91 1
SRPK1 92 4
HIPK1 92 6
CHK2 92 3
NEK6 92 4
MEKK1 93 8
EF2K 93 13
JNK3 93 6
p38 gamma MAPK 93 4
DYRK3 93 6
LKB1 93 5
VEGFR1 95 2
p38 alpha MAPK 95 8
TTK 95 4
RSK1 95 1
PKC alpha 96 0
CHK1 96 1
MST2 96 2
CAMKK beta 97 4
MKK1 97 16
ERK2 98 2
JNK1 98 6
CDK2-Cyclin A 98 4
MAPKAP-K2 98 12
IRR 99 6
PHK 99 5
p38 beta MAPK 99 9
PKB alpha 99 5
PIM1 100 0
TAK1 100 7
EPH-A4 100 4
STK33 100 0
Aurora B 100 2
MARK3 101 7
PKC gamma 101 6
MNK1 101 3
MKK6 102 5
MLK3 102 8
TAO1 102 11
PIM2 103 6
TrkA 103 1
EPH-A2 103 8
BRK 104 4
MPSK1 104 2
EPH-B3 104 0
PAK5 104 3
AMPK 104 9
CSK 104 1
MKK2 104 10
MLK1 105 6
NUAK1 105 2
Src 105 11
PAK6 105 11
CAMK1 106 13
PKC zeta 106 2
CLK2 106 4
PLK1 106 1
Lck 106 11
IKK epsilon 106 3
MINK1 107 14
BTK 107 25
PKD1 107 4
PDK1 107 4
IR 107 7
ERK1 108 23
MELK 108 2
HIPK2 108 8
DAPK1 109 7
PKA 110 2
ROCK 2 110 1
MSK1 110 6
NEK2a 110 3
ABL 110 3
MNK2 111 3
TBK1 111 13
PAK2 113 2
S6K1 114 8
BRSK1 114 4
MARK1 114 12
ASK1 115 8
EPH-B2 115 5
FGF-R1 115 6
MAPKAP-K3 115 13
ZAP70 116 2
DYRK2 116 3
Aurora A 116 3
MST4 116 7
JAK2 118 14
PIM3 118 4
HIPK3 118 13
RIPK2 119 8
EPH-B4 122 7
YES1 123 1
EPH-B1 126 14
HER4 127 6
BRSK2 130 7
SYK 134 4
TIE2 141 5

Do you need any help? Please get in touch and we’ll be happy to lend a hand.