Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Rigel TRAF6 Inhibitor C16H12ClF4N5O3S 465.81 TRAF6 WO2008115259 Download

Results as Barchart

View results as a bar chart
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
IRAK4 66 0
PRK2 69 1
MNK1 70 15
IKK epsilon 70 26
SGK1 70 1
p38 gamma MAPK 72 2
DYRK1A 72 6
p38 alpha MAPK 74 9
NEK6 78 14
VEGFR1 78 4
EF2K 79 15
CK1 delta 79 9
CK2 79 7
ERK8 79 0
TTK 80 1
GCK 80 6
PKC alpha 82 16
MST2 82 0
SRPK1 82 3
PAK4 83 10
CAMKK beta 83 4
PKB beta 84 2
GSK3 beta 85 14
p38 delta MAPK 85 3
PRAK 85 9
TBK1 85 12
MARK4 85 11
MEKK1 85 8
ZAP70 85 3
EPH-B3 86 9
RSK2 86 4
MAPKAP-K2 86 9
BTK 86 9
ERK1 86 2
JNK2 87 3
CDK2-Cyclin A 88 3
PIM1 88 2
JNK1 88 2
IKK beta 89 2
MINK1 89 3
MLK3 89 8
NUAK1 90 4
EPH-A4 90 4
RSK1 90 2
CSK 90 0
MAPKAP-K3 90 5
ERK2 90 5
PHK 90 5
DYRK3 91 3
PAK5 92 2
MNK2 92 6
AMPK 92 3
CAMK1 92 4
JNK3 93 0
CHK2 93 5
Lck 93 10
IGF-1R 93 15
IR 93 12
HIPK1 94 0
EPH-A2 94 29
PKC zeta 94 2
MPSK1 94 1
SYK 94 1
CLK2 95 18
MARK2 95 7
MKK6 95 1
S6K1 95 0
ROCK 2 95 1
DAPK1 96 22
CHK1 96 1
Aurora B 96 5
HIPK2 97 1
STK33 97 1
LKB1 97 14
PKB alpha 97 6
PIM2 97 5
JAK2 97 7
TAO1 98 8
PKC gamma 98 1
TAK1 98 8
PAK2 98 7
PLK1 99 5
Aurora A 99 0
MKK1 99 2
MKK2 99 12
ASK1 101 3
BRK 101 15
p38 beta MAPK 101 12
HIPK3 101 3
EPH-B2 102 5
NEK2a 102 0
IRR 102 4
MSK1 103 22
PDK1 103 11
TrkA 103 0
PKA 103 7
MST4 104 5
HER4 105 14
YES1 105 4
FGF-R1 106 9
MARK3 106 10
MELK 107 10
DYRK2 107 4
MLK1 108 1
BRSK2 108 7
RIPK2 109 2
PAK6 109 9
MARK1 109 12
BRSK1 109 2
Src 111 5
ABL 111 0
TIE2 112 0
PKD1 112 14
SmMLCK 112 2
PIM3 116 9
EPH-B1 117 1
EPH-B4 117 21

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