Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Rigel TRAF6 Inhibitor C16H12ClF4N5O3S 465.81 TRAF6 WO2008115259 Download

Results as Barchart

View results as a bar chart
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 99 2
MKK2 99 12
MKK6 95 1
ERK1 86 2
ERK2 90 5
JNK1 88 2
JNK2 87 3
JNK3 93 0
p38 alpha MAPK 74 9
p38 beta MAPK 101 12
p38 gamma MAPK 72 2
p38 delta MAPK 85 3
ERK8 79 0
RSK1 90 2
RSK2 86 4
PDK1 103 11
PKB alpha 97 6
PKB beta 84 2
SGK1 70 1
S6K1 95 0
PKA 103 7
ROCK 2 95 1
PRK2 69 1
PKC alpha 82 16
PKC gamma 98 1
PKC zeta 94 2
PKD1 112 14
STK33 97 1
MSK1 103 22
MNK1 70 15
MNK2 92 6
MAPKAP-K2 86 9
MAPKAP-K3 90 5
PRAK 85 9
CAMKK beta 83 4
CAMK1 92 4
SmMLCK 112 2
PHK 90 5
DAPK1 96 22
CHK1 96 1
CHK2 93 5
GSK3 beta 85 14
CDK2-Cyclin A 88 3
PLK1 99 5
Aurora A 99 0
Aurora B 96 5
LKB1 97 14
AMPK 92 3
MARK1 109 12
MARK2 95 7
MARK3 106 10
MARK4 85 11
BRSK1 109 2
BRSK2 108 7
MELK 107 10
NUAK1 90 4
CK1 delta 79 9
CK2 79 7
DYRK1A 72 6
DYRK2 107 4
DYRK3 91 3
NEK2a 102 0
NEK6 78 14
IKK beta 89 2
IKK epsilon 70 26
TBK1 85 12
PIM1 88 2
PIM2 97 5
PIM3 116 9
SRPK1 82 3
EF2K 79 15
HIPK1 94 0
HIPK2 97 1
HIPK3 101 3
CLK2 95 18
PAK2 98 7
PAK4 83 10
PAK5 92 2
PAK6 109 9
MST2 82 0
MST4 104 5
GCK 80 6
MINK1 89 3
MEKK1 85 8
MLK1 108 1
MLK3 89 8
TAO1 98 8
ASK1 101 3
TAK1 98 8
IRAK4 66 0
RIPK2 109 2
TTK 80 1
MPSK1 94 1
Src 111 5
Lck 93 10
CSK 90 0
YES1 105 4
ABL 111 0
BTK 86 9
JAK2 97 7
SYK 94 1
ZAP70 85 3
TIE2 112 0
BRK 101 15
EPH-A2 94 29
EPH-A4 90 4
EPH-B1 117 1
EPH-B2 102 5
EPH-B3 86 9
EPH-B4 117 21
FGF-R1 106 9
HER4 105 14
IGF-1R 93 15
IR 93 12
IRR 102 4
TrkA 103 0
VEGFR1 78 4

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