Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
IKK Inhibitor VII C28H29N5OS 483.6 IKK Waelchli R. (2006) Bioorg. Med. Chem. Lett. 16 108 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
JAK2 1 0
ERK8 1 0
TAK1 2 1
CDK2-Cyclin A 3 1
CLK2 3 0
DYRK2 3 1
Aurora A 3 1
IKK beta 3 0
IGF-1R 3 1
IR 3 1
Lck 3 1
DAPK1 4 0
EPH-B1 4 1
SGK1 4 1
ROCK 2 5 1
MLK3 5 0
PRK2 6 1
GSK3 beta 6 1
EPH-B3 6 1
IKK epsilon 6 1
HIPK1 8 0
CAMK1 8 2
HIPK2 8 3
EPH-B2 8 0
RIPK2 9 1
CHK1 10 1
DYRK3 10 0
MINK1 10 3
VEGFR1 11 1
HIPK3 11 2
SYK 11 1
EPH-B4 11 2
GCK 12 0
PHK 14 1
Src 14 6
JNK1 14 0
TrkA 14 2
BTK 16 2
EPH-A4 16 0
MARK3 16 1
Aurora B 17 4
TBK1 17 5
PKD1 18 3
YES1 19 4
NUAK1 19 3
MKK1 19 2
p38 beta MAPK 20 7
FGF-R1 20 8
AMPK 22 4
DYRK1A 24 1
RSK1 24 1
PIM3 24 1
TAO1 25 5
BRSK2 25 1
PKC alpha 26 4
MNK1 27 2
PAK5 27 0
PIM1 27 1
IRR 27 8
CSK 28 2
S6K1 29 2
CK2 30 4
EPH-A2 30 4
MST2 30 2
ASK1 32 6
MARK4 32 2
MARK1 33 4
TTK 33 1
MLK1 34 4
JNK3 35 5
PAK4 36 5
JNK2 37 2
MNK2 37 4
HER4 37 8
PRAK 38 1
PAK2 38 6
IRAK4 38 5
RSK2 39 1
SmMLCK 41 3
MKK2 42 3
MSK1 43 1
BRSK1 43 0
PKB beta 44 6
CAMKK beta 46 5
PKB alpha 47 1
ERK2 51 0
NEK2a 54 1
EF2K 55 7
MELK 58 10
PLK1 60 10
p38 delta MAPK 61 11
PDK1 61 0
CHK2 62 0
ERK1 64 9
PKA 67 8
MARK2 68 6
MEKK1 68 4
p38 gamma MAPK 69 7
MKK6 71 6
MAPKAP-K3 71 5
CK1 delta 72 1
NEK6 76 7
LKB1 77 3
p38 alpha MAPK 81 2
PKC zeta 81 6
PAK6 85 7
SRPK1 90 2
PIM2 91 6
MAPKAP-K2 93 6
MST4 156 6
Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
JAK2 2 1
ERK8 6 2
IKK beta 6 1
DAPK1 6 2
MLK3 7 0
CDK2-Cyclin A 12 1
HIPK2 12 2
TAK1 13 2
CLK2 15 1
VEGFR1 15 2
IKK epsilon 15 3
DYRK2 16 2
Lck 16 1
Aurora A 17 2
TrkA 18 2
IR 20 3
TBK1 23 2
GSK3 beta 24 3
SGK1 24 2
YES1 25 4
EPH-B3 26 0
NUAK1 26 1
EPH-B1 26 2
PRK2 27 3
ROCK 2 29 0
SYK 30 2
MLK1 30 1
PKD1 32 0
RIPK2 34 3
EPH-B2 35 2
HIPK1 35 2
MINK1 35 3
Src 36 4
EPH-B4 37 3
IGF-1R 37 6
DYRK3 37 2
GCK 39 2
JNK3 41 5
MARK4 42 12
EPH-A2 42 2
MNK1 43 6
FGF-R1 44 4
MNK2 45 4
EPH-A4 45 2
MARK3 47 0
BTK 47 2
CAMK1 48 5
HIPK3 49 4
AMPK 49 0
BRSK1 50 5
JNK1 51 3
Aurora B 52 2
MARK1 52 0
BRSK2 52 3
IRR 54 6
TAO1 57 2
HER4 57 10
TTK 57 4
PHK 57 5
CHK1 57 2
CSK 60 4
MKK1 60 0
PAK5 64 3
PIM3 64 1
p38 beta MAPK 65 4
PAK4 65 2
CK2 66 1
PKB alpha 67 3
CAMKK beta 69 6
ERK1 69 8
S6K1 69 7
DYRK1A 70 3
PKC alpha 71 2
PAK2 71 11
MSK1 72 12
PRAK 72 2
PKB beta 73 7
MST2 74 8
JNK2 74 7
RSK1 75 12
MARK2 75 2
EF2K 77 0
p38 delta MAPK 77 3
PAK6 77 5
PIM1 78 5
ERK2 78 1
IRAK4 79 8
MEKK1 79 2
ASK1 80 1
LKB1 80 12
PKA 80 1
PDK1 82 5
RSK2 83 0
PLK1 84 1
NEK6 85 0
MKK2 85 7
p38 gamma MAPK 86 4
SmMLCK 87 1
NEK2a 88 0
CK1 delta 89 0
p38 alpha MAPK 91 12
SRPK1 92 7
MKK6 94 5
PIM2 95 2
MAPKAP-K2 96 3
PKC zeta 98 6
CHK2 98 0
MAPKAP-K3 100 3
MELK 105 3
MST4 143 2

Do you need any help? Please get in touch and we’ll be happy to lend a hand.