Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
TG003 C13H15NO2S 249.33 Cdc2-like kinase Muraki M. (2004) J. Biol. Chem. 279 24246-24254 Sigma Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 98 4
MKK2 80 4
MKK6 119 11
ERK1 104 11
ERK2 80 8
JNK1 92 1
JNK2 95 5
JNK3 96 8
p38 alpha MAPK 83 2
p38 beta MAPK 93 0
p38 gamma MAPK 82 5
p38 delta MAPK 69 3
ERK8 23 3
RSK1 73 4
RSK2 89 9
PDK1 104 4
PKB alpha 87 6
PKB beta 83 5
SGK1 103 1
S6K1 94 5
PKA 93 4
ROCK 2 90 0
PRK2 74 10
PKC alpha 109 4
PKC zeta 97 7
PKD1 22 2
MSK1 79 9
MNK1 99 14
MNK2 103 2
MAPKAP-K2 101 4
MAPKAP-K3 97 7
PRAK 97 3
CAMKK beta 91 0
CAMK1 82 5
SmMLCK 82 6
PHK 105 3
DAPK1 74 6
CHK1 99 5
CHK2 72 1
GSK3 beta 41 3
CDK2-Cyclin A 103 9
PLK1 108 1
Aurora A 106 13
Aurora B 97 11
LKB1 79 7
AMPK 92 9
MARK1 86 7
MARK2 85 12
MARK3 95 9
MARK4 86 3
BRSK1 84 5
BRSK2 99 4
MELK 61 11
NUAK1 88 14
CK1 delta 9 0
CK2 73 5
DYRK1A 3 0
DYRK2 2 0
DYRK3 6 0
NEK2a 81 12
NEK6 108 6
IKK beta 92 9
IKK epsilon 105 6
TBK1 87 9
PIM1 11 2
PIM2 47 5
PIM3 12 1
SRPK1 94 0
EF2K 96 4
HIPK1 86 3
HIPK2 60 3
HIPK3 87 6
CLK2 3 0
PAK2 97 10
PAK4 99 1
PAK5 89 2
PAK6 93 2
MST2 101 14
MST4 120 15
GCK 72 6
MINK1 82 8
MEKK1 101 12
MLK1 105 2
MLK3 85 2
TAO1 49 2
ASK1 98 1
TAK1 82 1
IRAK4 98 3
RIPK2 63 11
TTK 68 5
Src 83 2
Lck 109 9
CSK 88 10
YES1 100 6
BTK 91 2
JAK2 95 6
SYK 110 12
EPH-A2 104 11
EPH-A4 118 10
EPH-B1 112 9
EPH-B2 110 5
EPH-B3 105 7
EPH-B4 100 14
FGF-R1 116 11
HER4 95 9
IGF-1R 113 13
IR 118 2
IRR 39 6
TrkA 98 12
VEGFR1 85 13
Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 99 4
MKK2 107 6
MKK6 92 7
ERK1 114 15
ERK2 74 1
JNK1 92 4
JNK2 104 10
JNK3 105 6
p38 alpha MAPK 80 0
p38 beta MAPK 97 2
p38 gamma MAPK 128 3
p38 delta MAPK 104 1
ERK8 93 9
RSK1 101 7
RSK2 79 2
PDK1 101 3
PKB alpha 107 7
PKB beta 88 8
SGK1 101 6
S6K1 99 3
PKA 91 5
ROCK 2 88 1
PRK2 97 2
PKC alpha 109 8
PKC zeta 106 6
PKD1 57 2
MSK1 115 4
MNK1 95 10
MNK2 109 4
MAPKAP-K2 116 6
MAPKAP-K3 119 5
PRAK 117 12
CAMKK beta 100 6
CAMK1 82 1
SmMLCK 82 3
PHK 108 2
DAPK1 80 10
CHK1 117 3
CHK2 109 0
GSK3 beta 86 10
CDK2-Cyclin A 129 3
PLK1 119 6
Aurora A 105 9
Aurora B 98 10
LKB1 113 2
AMPK 114 8
MARK1 91 10
MARK2 89 4
MARK3 94 7
MARK4 94 13
BRSK1 113 5
BRSK2 98 4
MELK 119 3
NUAK1 82 3
CK1 delta 19 0
CK2 107 6
DYRK1A 16 0
DYRK2 12 3
DYRK3 23 10
NEK2a 77 1
NEK6 105 6
IKK beta 98 1
IKK epsilon 106 2
TBK1 118 1
PIM1 21 2
PIM2 105 7
PIM3 30 1
SRPK1 91 2
EF2K 115 10
HIPK1 104 5
HIPK2 98 7
HIPK3 114 10
CLK2 18 1
PAK2 105 2
PAK4 94 1
PAK5 113 0
PAK6 105 12
MST2 104 9
MST4 106 1
GCK 112 3
MINK1 122 14
MEKK1 109 10
MLK1 108 14
MLK3 93 6
TAO1 70 9
ASK1 97 0
TAK1 118 4
IRAK4 112 4
RIPK2 100 5
TTK 72 4
Src 79 3
Lck 105 14
CSK 112 5
YES1 100 4
BTK 115 8
JAK2 110 11
SYK 109 8
EPH-A2 116 10
EPH-A4 116 13
EPH-B1 105 9
EPH-B2 128 4
EPH-B3 91 14
EPH-B4 116 1
FGF-R1 86 9
HER4 94 11
IGF-1R 120 11
IR 123 14
IRR 45 2
TrkA 111 7
VEGFR1 89 5

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