Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
A-83-01 C25H19N5S 421.52 ALK5 Tojo (2005) Cancer.Sci. 96 791 Tocris Download

Results as Barchart

View results as a bar chart
0.1µM
1µM

Results as Table

Screening Concentration: 0.1µM
Kinase % Activity Remainingsort ascending Standard Deviation
MEKK1 130 15
RSK2 126 3
MARK2 121 8
Aurora A 120 7
JNK3 119 3
TrkA 118 2
MAPKAP-K2 117 3
BRSK2 117 6
CHK2 115 10
TTK 113 0
PRAK 113 7
EPH-B2 113 2
IKK epsilon 112 5
EPH-B3 112 6
MELK 111 2
JNK1 111 3
PAK2 111 17
PAK6 111 12
MKK1 111 20
MSK1 110 6
BTK 110 5
RSK1 110 6
BRSK1 110 12
PKA 109 2
DYRK1A 109 11
NEK2a 109 8
SYK 109 10
IR 108 7
ERK8 108 16
EPH-A4 108 1
PKB beta 108 3
S6K1 108 2
CHK1 107 10
PAK5 107 2
NEK6 107 3
IKK beta 107 1
MST2 107 0
JAK2 107 18
MAPKAP-K3 107 3
MARK1 107 3
SGK1 107 1
CLK2 106 10
YES1 106 4
JNK2 105 6
PRK2 105 12
HIPK3 105 8
Lck 105 7
EPH-A2 105 5
PIM1 105 3
ERK1 105 15
ERK2 104 11
HER4 104 1
HIPK2 104 8
SmMLCK 104 8
MLK3 104 2
MNK1 103 1
PDK1 103 8
CAMK1 103 18
EF2K 102 4
CK2 102 0
Src 102 1
p38 gamma MAPK 102 13
DYRK3 102 8
TBK1 102 7
PKB alpha 102 5
IRAK4 101 3
LKB1 101 5
MARK3 101 4
SRPK1 101 7
DYRK2 100 0
CAMKK beta 100 10
PHK 100 11
TAK1 99 9
GSK3 beta 99 1
PLK1 99 11
AMPK 99 3
PKC zeta 98 0
IRR 98 5
Aurora B 98 5
GCK 98 3
MARK4 98 2
IGF-1R 97 5
PKC alpha 97 5
CSK 97 2
PIM2 97 4
ROCK 2 96 2
NUAK1 96 10
HIPK1 96 4
MLK1 96 7
MST4 95 2
DAPK1 94 3
CDK2-Cyclin A 93 4
EPH-B4 93 2
p38 delta MAPK 91 20
PIM3 91 4
CK1 delta 90 8
p38 beta MAPK 89 15
PAK4 89 6
MNK2 81 5
PKD1 80 1
MINK1 66 2
FGF-R1 64 3
p38 alpha MAPK 56 1
VEGFR1 27 0
RIPK2 26 6
Screening Concentration: 1µM
Kinase % Activity Remainingsort ascending Standard Deviation
PIM3 117 11
PAK6 113 19
MARK1 113 7
PHK 112 4
MEKK1 111 0
MARK2 110 9
CHK2 110 6
RSK2 109 8
MAPKAP-K2 108 2
CAMK1 107 13
MLK3 107 4
Aurora A 107 3
IKK epsilon 106 0
SYK 106 2
TBK1 106 1
PKB alpha 106 9
PLK1 106 7
S6K1 105 13
MELK 105 3
CHK1 105 3
BTK 104 5
CAMKK beta 104 2
EPH-B3 104 0
ROCK 2 104 2
CK2 104 11
DYRK1A 104 1
SGK1 103 14
IGF-1R 103 11
IRR 103 3
Aurora B 102 1
PAK5 102 4
PKC alpha 102 7
CDK2-Cyclin A 102 11
JNK1 101 4
PAK2 101 12
MSK1 101 0
NEK6 100 5
IKK beta 100 12
MST2 100 6
ERK1 100 5
EF2K 100 3
PKC zeta 100 3
LKB1 99 11
MST4 99 1
PRAK 99 16
PKA 99 5
IRAK4 99 5
JNK3 99 7
HIPK3 99 1
TrkA 99 11
MARK3 98 7
EPH-A4 98 3
MKK1 98 1
HIPK1 98 11
TTK 98 6
CLK2 98 0
MAPKAP-K3 97 4
PIM1 97 4
PKB beta 96 5
RSK1 95 2
EPH-B2 95 5
BRSK1 95 7
HIPK2 95 12
DYRK2 95 7
p38 delta MAPK 94 4
PIM2 94 3
ERK2 94 2
IR 94 6
MNK1 93 1
ERK8 93 4
JAK2 93 4
EPH-B4 93 19
DYRK3 93 4
PAK4 93 4
CSK 93 1
NEK2a 92 3
EPH-A2 92 14
BRSK2 92 14
MNK2 91 2
PRK2 91 3
DAPK1 90 2
JNK2 90 7
SmMLCK 89 1
PDK1 88 0
p38 gamma MAPK 88 8
MARK4 87 2
MLK1 86 2
SRPK1 84 1
NUAK1 84 4
AMPK 82 4
HER4 82 15
TAK1 81 9
GSK3 beta 79 4
Src 75 1
YES1 70 5
GCK 68 7
Lck 62 3
p38 beta MAPK 61 7
CK1 delta 46 5
FGF-R1 37 2
PKD1 32 9
p38 alpha MAPK 16 1
MINK1 13 2
RIPK2 9 3
VEGFR1 8 1

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