Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
PP3 C11H9N5 211.22 Src Hou (2007) Neurosci Lett 420 235 Tocris Download

Results as Barchart

View results as a bar chart
20µM
10µM

Results as Table

Screening Concentration: 20µM
Kinase % Activity Remainingsort descending Standard Deviation
CK1 delta 14 4
MNK1 24 4
CK2 26 6
DYRK1A 30 4
DYRK2 30 3
RIPK2 31 3
DYRK3 32 1
BRSK1 40 0
Lck 48 7
IRR 48 5
HER4 50 4
ROCK 2 52 0
BRSK2 52 5
EF2K 53 4
MINK1 54 6
MLK1 54 1
NUAK1 55 0
ERK8 56 5
GCK 57 4
MLK3 57 0
PRK2 58 4
BTK 59 5
IR 60 6
Src 61 0
Aurora B 61 4
HIPK2 64 1
YES1 64 12
S6K1 65 1
IGF-1R 66 9
Aurora A 66 0
MELK 67 25
SmMLCK 69 33
PIM3 69 1
IRAK4 72 0
PHK 73 0
PKA 74 6
PAK4 74 5
TTK 75 2
ERK2 77 2
PKC alpha 77 5
IKK beta 77 7
PIM1 77 3
PAK5 78 8
MARK3 78 0
MST2 81 11
LKB1 81 0
MNK2 81 15
SGK1 83 0
PKD1 83 0
p38 beta MAPK 84 6
JNK1 88 8
MSK1 88 12
MARK2 88 4
p38 alpha MAPK 89 8
CAMK1 89 4
MARK4 90 6
CDK2-Cyclin A 91 6
PLK1 91 2
TBK1 91 4
NEK6 92 18
IKK epsilon 92 6
RSK2 92 19
PDK1 92 6
SRPK1 92 33
p38 delta MAPK 93 7
PIM2 93 5
MKK1 94 13
PRAK 94 17
PKB alpha 94 3
HIPK1 95 4
VEGFR1 95 7
EPH-B3 95 10
ERK1 96 22
FGF-R1 96 1
CAMKK beta 96 10
CHK1 97 8
JNK3 97 12
CSK 98 9
AMPK 98 6
PKB beta 98 34
PKC zeta 99 1
MAPKAP-K3 101 4
EPH-A2 102 14
PAK6 103 6
RSK1 103 7
GSK3 beta 104 18
CHK2 107 20
PAK2 107 11
p38 gamma MAPK 108 4
MAPKAP-K2 110 4
JNK2 111 2
NEK2a 115 4
HIPK3 117 3
MST4 119 3
SYK 120 15
Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
CK1 delta 19 1
MNK1 34 1
CK2 38 1
RIPK2 42 4
DYRK3 47 4
DYRK1A 52 8
DYRK2 53 7
IRR 60 3
BRSK1 60 1
EF2K 64 6
ROCK 2 65 8
HER4 67 5
GCK 67 10
ERK8 68 7
NUAK1 69 0
BRSK2 69 4
PRK2 70 11
S6K1 73 2
Lck 75 11
HIPK2 76 4
IGF-1R 77 6
MINK1 77 15
RSK2 79 7
YES1 80 4
NEK6 80 2
PRAK 80 10
Src 81 13
IKK beta 82 3
MARK4 82 3
PAK4 83 9
Aurora A 83 9
Aurora B 83 10
MLK1 83 0
MLK3 83 10
IRAK4 83 5
BTK 83 22
TTK 83 5
ERK1 84 8
ERK2 85 24
PIM1 85 12
SGK1 86 1
IR 87 13
CAMK1 87 18
MNK2 88 9
MARK3 88 10
PHK 89 0
PIM2 89 1
MSK1 90 2
PIM3 90 1
PKA 91 4
CDK2-Cyclin A 91 10
p38 delta MAPK 91 1
PAK5 92 1
GSK3 beta 93 2
p38 alpha MAPK 94 2
SmMLCK 94 12
MELK 94 17
JNK1 95 3
PKC alpha 95 3
IKK epsilon 95 8
CHK1 96 7
PKC zeta 96 6
PLK1 96 11
p38 beta MAPK 96 8
MST2 96 13
MAPKAP-K3 97 11
JNK3 100 1
LKB1 100 14
MARK2 100 2
FGF-R1 101 18
p38 gamma MAPK 102 7
TBK1 103 2
PAK2 104 1
PDK1 104 5
AMPK 105 1
PKB alpha 105 7
RSK1 108 13
MAPKAP-K2 108 2
EPH-B3 108 7
PAK6 109 14
HIPK3 110 6
SYK 110 11
CSK 111 3
HIPK1 112 5
EPH-A2 113 10
PKB beta 113 11
VEGFR1 114 10
CHK2 115 6
CAMKK beta 116 11
MKK1 118 32
PKD1 121 23
NEK2a 121 1
SRPK1 121 14
MST4 124 8
JNK2 128 4

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