Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
PP3 C11H9N5 211.22 Src Hou (2007) Neurosci Lett 420 235 Tocris Download

Results as Barchart

View results as a bar chart
20µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 118 32
ERK1 84 8
ERK2 85 24
JNK1 95 3
JNK2 128 4
JNK3 100 1
p38 alpha MAPK 94 2
p38 beta MAPK 96 8
p38 gamma MAPK 102 7
p38 delta MAPK 91 1
ERK8 68 7
RSK1 108 13
RSK2 79 7
PDK1 104 5
PKB alpha 105 7
PKB beta 113 11
SGK1 86 1
S6K1 73 2
PKA 91 4
ROCK 2 65 8
PRK2 70 11
PKC alpha 95 3
PKC zeta 96 6
PKD1 121 23
MSK1 90 2
MNK1 34 1
MNK2 88 9
MAPKAP-K2 108 2
MAPKAP-K3 97 11
PRAK 80 10
CAMKK beta 116 11
CAMK1 87 18
SmMLCK 94 12
PHK 89 0
CHK1 96 7
CHK2 115 6
GSK3 beta 93 2
CDK2-Cyclin A 91 10
PLK1 96 11
Aurora A 83 9
Aurora B 83 10
LKB1 100 14
AMPK 105 1
MARK2 100 2
MARK3 88 10
MARK4 82 3
BRSK1 60 1
BRSK2 69 4
MELK 94 17
NUAK1 69 0
CK1 delta 19 1
CK2 38 1
DYRK1A 52 8
DYRK2 53 7
DYRK3 47 4
NEK2a 121 1
NEK6 80 2
IKK beta 82 3
IKK epsilon 95 8
TBK1 103 2
PIM1 85 12
PIM2 89 1
PIM3 90 1
SRPK1 121 14
EF2K 64 6
HIPK1 112 5
HIPK2 76 4
HIPK3 110 6
PAK2 104 1
PAK4 83 9
PAK5 92 1
PAK6 109 14
MST2 96 13
MST4 124 8
GCK 67 10
MINK1 77 15
MLK1 83 0
MLK3 83 10
IRAK4 83 5
RIPK2 42 4
TTK 83 5
Src 81 13
Lck 75 11
CSK 111 3
YES1 80 4
BTK 83 22
SYK 110 11
EPH-A2 113 10
EPH-B3 108 7
FGF-R1 101 18
HER4 67 5
IGF-1R 77 6
IR 87 13
IRR 60 3
VEGFR1 114 10
Screening Concentration: 20µM
Kinase % Activity Remaining Standard Deviation
MKK1 94 13
ERK1 96 22
ERK2 77 2
JNK1 88 8
JNK2 111 2
JNK3 97 12
p38 alpha MAPK 89 8
p38 beta MAPK 84 6
p38 gamma MAPK 108 4
p38 delta MAPK 93 7
ERK8 56 5
RSK1 103 7
RSK2 92 19
PDK1 92 6
PKB alpha 94 3
PKB beta 98 34
SGK1 83 0
S6K1 65 1
PKA 74 6
ROCK 2 52 0
PRK2 58 4
PKC alpha 77 5
PKC zeta 99 1
PKD1 83 0
MSK1 88 12
MNK1 24 4
MNK2 81 15
MAPKAP-K2 110 4
MAPKAP-K3 101 4
PRAK 94 17
CAMKK beta 96 10
CAMK1 89 4
SmMLCK 69 33
PHK 73 0
CHK1 97 8
CHK2 107 20
GSK3 beta 104 18
CDK2-Cyclin A 91 6
PLK1 91 2
Aurora A 66 0
Aurora B 61 4
LKB1 81 0
AMPK 98 6
MARK2 88 4
MARK3 78 0
MARK4 90 6
BRSK1 40 0
BRSK2 52 5
MELK 67 25
NUAK1 55 0
CK1 delta 14 4
CK2 26 6
DYRK1A 30 4
DYRK2 30 3
DYRK3 32 1
NEK2a 115 4
NEK6 92 18
IKK beta 77 7
IKK epsilon 92 6
TBK1 91 4
PIM1 77 3
PIM2 93 5
PIM3 69 1
SRPK1 92 33
EF2K 53 4
HIPK1 95 4
HIPK2 64 1
HIPK3 117 3
PAK2 107 11
PAK4 74 5
PAK5 78 8
PAK6 103 6
MST2 81 11
MST4 119 3
GCK 57 4
MINK1 54 6
MLK1 54 1
MLK3 57 0
IRAK4 72 0
RIPK2 31 3
TTK 75 2
Src 61 0
Lck 48 7
CSK 98 9
YES1 64 12
BTK 59 5
SYK 120 15
EPH-A2 102 14
EPH-B3 95 10
FGF-R1 96 1
HER4 50 4
IGF-1R 66 9
IR 60 6
IRR 48 5
VEGFR1 95 7

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