Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Quercetagetin C15H10O8 318.3 PIM1 Holder S. (2007) Mol. Cancer Ther. 6 163 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
10µM
1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 84 0
MKK2 94 1
MKK6 102 7
ERK1 101 2
ERK2 107 8
JNK1 93 1
JNK2 106 7
JNK3 107 2
p38 alpha MAPK 100 4
p38 beta MAPK 101 7
p38 gamma MAPK 107 2
p38 delta MAPK 96 7
ERK8 89 0
RSK1 51 0
RSK2 22 0
PDK1 104 0
PKB alpha 106 9
PKB beta 21 7
SGK1 87 3
S6K1 104 3
PKA 109 7
ROCK 2 95 4
PRK2 106 7
PKC alpha 99 7
PKC zeta 62 0
PKD1 69 3
MSK1 88 1
MNK1 61 2
MNK2 63 7
MAPKAP-K2 94 1
MAPKAP-K3 92 3
PRAK 87 1
CAMKK beta 72 0
CAMK1 49 1
SmMLCK 87 0
PHK 98 2
DAPK1 95 11
CHK1 92 12
CHK2 48 12
GSK3 beta 94 5
CDK2-Cyclin A 89 12
PLK1 107 11
Aurora A 95 11
Aurora B 62 4
LKB1 95 12
AMPK 73 6
MARK1 40 0
MARK2 86 2
MARK3 51 1
MARK4 34 1
BRSK1 82 1
BRSK2 71 10
MELK 53 3
NUAK1 33 7
CK1 delta 90 0
CK2 46 3
DYRK1A 71 11
DYRK2 45 2
DYRK3 59 3
NEK2a 86 3
NEK6 99 8
IKK beta 100 6
IKK epsilon 69 4
TBK1 54 4
PIM1 37 6
PIM2 74 1
PIM3 34 1
SRPK1 55 10
EF2K 110 8
HIPK1 93 5
HIPK2 62 7
HIPK3 88 10
CLK2 58 9
PAK2 96 7
PAK4 50 3
PAK5 67 0
PAK6 58 2
MST2 58 2
MST4 87 2
GCK 93 1
MINK1 56 4
MEKK1 67 4
MLK1 100 5
MLK3 62 1
TAO1 94 11
ASK1 118 0
TAK1 94 10
IRAK4 80 3
RIPK2 83 10
TTK 75 0
Src 38 0
Lck 102 15
CSK 125 12
YES1 42 1
BTK 61 2
JAK2 91 5
SYK 89 6
EPH-A2 94 14
EPH-A4 117 3
EPH-B1 85 8
EPH-B2 69 4
EPH-B3 93 5
EPH-B4 90 13
FGF-R1 27 1
HER4 109 4
IGF-1R 96 3
IR 86 0
IRR 76 4
TrkA 92 9
VEGFR1 27 4
Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 24 4
ERK1 54 4
ERK2 105 1
JNK1 93 3
JNK2 100 9
JNK3 89 1
p38 alpha MAPK 119 6
p38 beta MAPK 90 0
p38 gamma MAPK 88 6
p38 delta MAPK 97 8
ERK8 65 1
RSK1 15 0
RSK2 12 1
PDK1 83 13
PKB alpha 99 10
PKB beta 1 0
SGK1 24 2
S6K1 14 0
PKA 79 2
ROCK 2 56 3
PRK2 102 1
PKC alpha 80 13
PKC zeta 20 0
PKD1 15 6
MSK1 38 0
MNK1 12 4
MNK2 26 5
MAPKAP-K2 53 14
MAPKAP-K3 14 0
PRAK 1 0
CAMKK beta 61 5
CAMK1 19 3
SmMLCK 23 0
PHK 2 0
CHK1 32 1
CHK2 5 1
GSK3 beta 19 1
CDK2-Cyclin A 32 0
PLK1 23 4
Aurora A 28 2
Aurora B 8 1
LKB1 55 6
AMPK 9 3
MARK1 11 0
MARK2 26 3
MARK3 6 1
MARK4 20 0
BRSK1 7 0
BRSK2 13 1
MELK 9 1
NUAK1 12 0
CK1 delta 29 1
CK2 7 0
DYRK1A 3 0
DYRK2 1 0
DYRK3 2 0
NEK2a 13 1
NEK6 21 1
IKK beta 16 5
IKK epsilon 21 1
TBK1 64 10
PIM1 7 0
PIM2 11 0
PIM3 0 0
SRPK1 3 0
EF2K 109 1
HIPK1 11 1
HIPK2 19 0
HIPK3 55 0
PAK2 98 2
PAK4 38 6
PAK5 55 6
PAK6 60 12
MST2 9 0
MST4 58 5
GCK 23 1
MINK1 10 0
MEKK1 74 6
MLK1 24 0
MLK3 16 0
TAK1 5 2
IRAK4 46 0
RIPK2 7 0
TTK 36 6
Src 25 2
Lck 95 9
CSK 74 0
YES1 9 0
BTK 32 2
JAK2 13 7
SYK 93 8
EPH-A2 73 6
EPH-A4 74 6
EPH-B3 61 6
EPH-B4 56 11
FGF-R1 14 0
HER4 44 2
IGF-1R 43 2
IR 62 3
IRR 21 1
TrkA 29 2
VEGFR1 7 0

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