Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Sulfasalazine C18H14N4O5S 398.39 glutathione-S-transferase Liptay S. (1999) Br. J. Pharmacol. 128 1361 Volin M.V. (1999) Arthritis Rheum. 42 1927 Sigma Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
PIM3 18 3
CK2 29 1
PIM1 44 5
SGK1 54 0
MINK1 57 0
MLK3 71 4
BTK 74 1
PAK4 76 8
DYRK3 77 0
HER4 77 9
PIM2 77 4
DYRK2 79 7
MNK1 79 1
IRR 80 5
Src 83 1
DYRK1A 85 7
PKC alpha 85 2
MAPKAP-K3 85 9
NUAK1 86 9
BRSK2 87 7
TTK 88 4
IKK beta 89 0
MLK1 89 2
MARK4 89 16
ROCK 2 90 2
PRK2 90 8
PRAK 90 5
S6K1 90 5
RSK2 91 12
CAMK1 91 1
MKK1 91 11
MST2 92 11
BRSK1 92 8
GSK3 beta 93 8
PAK2 94 5
PKB beta 94 11
PHK 94 2
HIPK2 94 12
MSK1 95 1
RIPK2 95 4
CK1 delta 95 13
JNK1 96 6
PAK5 96 0
GCK 96 2
IR 97 13
NEK2a 97 12
NEK6 97 18
IRAK4 97 0
ERK2 97 2
Lck 97 3
IGF-1R 98 11
PAK6 99 3
MNK2 99 10
TBK1 99 1
SmMLCK 99 12
Aurora A 100 1
p38 gamma MAPK 100 2
p38 alpha MAPK 101 2
PKD1 101 2
MELK 101 7
PLK1 102 2
CHK2 103 13
HIPK3 103 0
YES1 103 4
PKC zeta 103 6
p38 delta MAPK 103 2
MST4 104 1
AMPK 104 25
SRPK1 104 6
Aurora B 105 12
VEGFR1 105 11
HIPK1 105 13
MAPKAP-K2 106 8
PKB alpha 106 3
JNK3 107 0
CDK2-Cyclin A 107 8
MARK2 107 15
SYK 107 2
p38 beta MAPK 109 6
ERK8 109 8
MARK3 109 5
EF2K 109 9
CHK1 109 10
ERK1 110 16
IKK epsilon 112 3
EPH-A2 112 20
PDK1 113 3
PKA 114 4
FGF-R1 115 19
JNK2 117 16
LKB1 117 17
EPH-B3 118 16
CSK 119 4
RSK1 122 10
CAMKK beta 122 16
Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
PIM3 63 1
MNK2 76 6
SGK1 76 11
S6K1 80 17
CK2 83 4
MINK1 84 23
MKK1 86 13
PIM1 88 5
PAK4 89 6
DYRK3 89 9
PKC alpha 90 3
IKK epsilon 92 2
PRAK 92 13
ROCK 2 93 6
CDK2-Cyclin A 93 8
PRK2 94 13
DYRK1A 94 2
MST2 94 16
Src 94 10
EF2K 95 18
JNK1 96 7
PKC zeta 96 4
p38 gamma MAPK 97 8
MNK1 97 3
RSK2 97 4
BRSK1 97 13
BTK 97 16
CAMK1 97 5
HIPK3 98 10
NEK6 98 12
MARK4 98 9
PIM2 98 18
TTK 98 14
DYRK2 99 8
PAK6 99 3
NEK2a 100 29
HER4 100 13
p38 delta MAPK 100 3
MAPKAP-K2 100 3
GSK3 beta 101 1
IR 101 17
IRR 101 22
AMPK 101 4
GCK 101 12
SYK 101 17
Lck 102 3
MST4 102 1
VEGFR1 102 7
EPH-B3 102 7
CK1 delta 103 14
PKD1 103 0
ERK1 103 4
ERK2 104 9
CHK1 104 11
PAK5 104 15
Aurora B 104 4
MLK3 104 22
IRAK4 104 4
PHK 104 16
JNK3 105 7
p38 alpha MAPK 105 11
MLK1 105 0
PLK1 106 5
BRSK2 106 11
SRPK1 106 1
IKK beta 107 11
NUAK1 107 13
CHK2 108 12
PAK2 108 2
MARK2 108 16
PDK1 108 19
MSK1 109 11
FGF-R1 110 12
PKB beta 110 28
PKA 111 8
IGF-1R 111 16
ERK8 111 10
TBK1 111 5
HIPK1 111 3
PKB alpha 112 8
SmMLCK 112 10
YES1 113 12
p38 beta MAPK 113 2
MELK 113 8
HIPK2 114 21
RIPK2 115 19
MAPKAP-K3 116 5
Aurora A 117 22
MARK3 117 6
CSK 119 13
EPH-A2 119 5
LKB1 124 8
CAMKK beta 127 1
JNK2 128 19
RSK1 129 3

Do you need any help? Please get in touch and we’ll be happy to lend a hand.