Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Sulfasalazine C18H14N4O5S 398.39 glutathione-S-transferase Liptay S. (1999) Br. J. Pharmacol. 128 1361 Volin M.V. (1999) Arthritis Rheum. 42 1927 Sigma Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 91 11
ERK1 110 16
ERK2 97 2
JNK1 96 6
JNK2 117 16
JNK3 107 0
p38 alpha MAPK 101 2
p38 beta MAPK 109 6
p38 gamma MAPK 100 2
p38 delta MAPK 103 2
ERK8 109 8
RSK1 122 10
RSK2 91 12
PDK1 113 3
PKB alpha 106 3
PKB beta 94 11
SGK1 54 0
S6K1 90 5
PKA 114 4
ROCK 2 90 2
PRK2 90 8
PKC alpha 85 2
PKC zeta 103 6
PKD1 101 2
MSK1 95 1
MNK1 79 1
MNK2 99 10
MAPKAP-K2 106 8
MAPKAP-K3 85 9
PRAK 90 5
CAMKK beta 122 16
CAMK1 91 1
SmMLCK 99 12
PHK 94 2
CHK1 109 10
CHK2 103 13
GSK3 beta 93 8
CDK2-Cyclin A 107 8
PLK1 102 2
Aurora A 100 1
Aurora B 105 12
LKB1 117 17
AMPK 104 25
MARK2 107 15
MARK3 109 5
MARK4 89 16
BRSK1 92 8
BRSK2 87 7
MELK 101 7
NUAK1 86 9
CK1 delta 95 13
CK2 29 1
DYRK1A 85 7
DYRK2 79 7
DYRK3 77 0
NEK2a 97 12
NEK6 97 18
IKK beta 89 0
IKK epsilon 112 3
TBK1 99 1
PIM1 44 5
PIM2 77 4
PIM3 18 3
SRPK1 104 6
EF2K 109 9
HIPK1 105 13
HIPK2 94 12
HIPK3 103 0
PAK2 94 5
PAK4 76 8
PAK5 96 0
PAK6 99 3
MST2 92 11
MST4 104 1
GCK 96 2
MINK1 57 0
MLK1 89 2
MLK3 71 4
IRAK4 97 0
RIPK2 95 4
TTK 88 4
Src 83 1
Lck 97 3
CSK 119 4
YES1 103 4
BTK 74 1
SYK 107 2
EPH-A2 112 20
EPH-B3 118 16
FGF-R1 115 19
HER4 77 9
IGF-1R 98 11
IR 97 13
IRR 80 5
VEGFR1 105 11
Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 86 13
ERK1 103 4
ERK2 104 9
JNK1 96 7
JNK2 128 19
JNK3 105 7
p38 alpha MAPK 105 11
p38 beta MAPK 113 2
p38 gamma MAPK 97 8
p38 delta MAPK 100 3
ERK8 111 10
RSK1 129 3
RSK2 97 4
PDK1 108 19
PKB alpha 112 8
PKB beta 110 28
SGK1 76 11
S6K1 80 17
PKA 111 8
ROCK 2 93 6
PRK2 94 13
PKC alpha 90 3
PKC zeta 96 4
PKD1 103 0
MSK1 109 11
MNK1 97 3
MNK2 76 6
MAPKAP-K2 100 3
MAPKAP-K3 116 5
PRAK 92 13
CAMKK beta 127 1
CAMK1 97 5
SmMLCK 112 10
PHK 104 16
CHK1 104 11
CHK2 108 12
GSK3 beta 101 1
CDK2-Cyclin A 93 8
PLK1 106 5
Aurora A 117 22
Aurora B 104 4
LKB1 124 8
AMPK 101 4
MARK2 108 16
MARK3 117 6
MARK4 98 9
BRSK1 97 13
BRSK2 106 11
MELK 113 8
NUAK1 107 13
CK1 delta 103 14
CK2 83 4
DYRK1A 94 2
DYRK2 99 8
DYRK3 89 9
NEK2a 100 29
NEK6 98 12
IKK beta 107 11
IKK epsilon 92 2
TBK1 111 5
PIM1 88 5
PIM2 98 18
PIM3 63 1
SRPK1 106 1
EF2K 95 18
HIPK1 111 3
HIPK2 114 21
HIPK3 98 10
PAK2 108 2
PAK4 89 6
PAK5 104 15
PAK6 99 3
MST2 94 16
MST4 102 1
GCK 101 12
MINK1 84 23
MLK1 105 0
MLK3 104 22
IRAK4 104 4
RIPK2 115 19
TTK 98 14
Src 94 10
Lck 102 3
CSK 119 13
YES1 113 12
BTK 97 16
SYK 101 17
EPH-A2 119 5
EPH-B3 102 7
FGF-R1 110 12
HER4 100 13
IGF-1R 111 16
IR 101 17
IRR 101 22
VEGFR1 102 7

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