Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Akt Inhibitor IV C31H27IN4S 614.6 Akt Kau T. R. (2003) Cancer Cell 4 463 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
CAMK1 22 1
SGK1 40 10
MKK1 42 0
S6K1 44 9
Lck 45 3
RSK1 47 4
PIM3 50 0
PKD1 50 12
NEK6 52 14
PKB alpha 53 24
MLK1 54 9
SmMLCK 56 3
SYK 59 16
MSK1 61 6
IGF-1R 62 0
MELK 63 9
NEK2a 63 12
GCK 64 0
DYRK2 64 2
IRAK4 64 0
PIM1 64 0
MINK1 65 0
IKK beta 65 0
MST4 68 7
CHK1 70 6
DYRK1A 71 7
EPH-A2 72 6
CSK 74 2
PHK 74 5
MNK2 75 2
PKC alpha 75 0
TBK1 76 2
PRK2 76 7
ROCK 2 77 9
PKC zeta 78 2
SRPK1 78 33
EPH-B3 79 0
PKB beta 79 2
p38 gamma MAPK 80 1
HIPK2 80 1
Aurora B 82 6
ERK8 85 4
MAPKAP-K2 85 4
IRR 88 2
MLK3 88 1
p38 alpha MAPK 88 6
MST2 88 5
IR 88 18
LKB1 89 6
CDK2-Cyclin A 89 0
MARK3 89 1
DYRK3 90 0
CHK2 90 4
PIM2 90 12
IKK epsilon 91 16
CAMKK beta 91 4
FGF-R1 91 2
PKA 91 4
JNK2 91 3
TTK 92 1
AMPK 92 8
PAK4 94 11
CK2 95 3
GSK3 beta 95 5
p38 delta MAPK 95 11
PRAK 96 20
ERK2 96 1
RSK2 99 7
MNK1 99 8
ERK1 100 7
JNK1 100 9
p38 beta MAPK 100 4
BRSK2 101 4
Src 103 8
HER4 104 5
CK1 delta 108 10
NUAK1 111 4
YES1 112 6
PAK6 113 3
PAK5 116 4
PDK1 126 3
VEGFR1 126 15
EF2K 130 1
PLK1 144 2
BTK 148 30
Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
SGK1 65 16
MKK1 68 0
HER4 70 1
IKK beta 72 0
EPH-B3 74 3
Lck 74 0
PIM3 79 9
BRSK2 79 10
MLK1 80 10
SRPK1 80 36
RSK1 80 4
GCK 80 1
S6K1 83 4
IRAK4 83 2
EPH-A2 86 11
CDK2-Cyclin A 88 1
DYRK2 88 0
SmMLCK 89 5
CHK1 89 4
SYK 89 9
MNK2 89 3
PHK 90 0
FGF-R1 90 14
PIM1 90 10
Src 90 10
MSK1 91 6
ERK8 91 5
TBK1 91 8
NEK6 92 6
PKB beta 93 1
ERK2 93 5
MNK1 93 2
IR 93 10
MAPKAP-K2 93 1
CSK 94 11
MST4 94 12
PRAK 94 8
CAMK1 94 2
JNK2 95 6
IGF-1R 95 6
p38 delta MAPK 95 8
Aurora B 96 7
MINK1 97 15
LKB1 97 9
PKC alpha 97 2
IKK epsilon 97 11
AMPK 98 0
BTK 98 4
CK1 delta 98 2
DYRK3 99 1
CHK2 99 11
ROCK 2 99 3
PRK2 99 1
PIM2 99 1
p38 alpha MAPK 99 1
PKC zeta 99 4
p38 gamma MAPK 99 6
MARK3 99 10
PAK6 99 1
DYRK1A 99 6
PKB alpha 99 16
JNK1 100 6
YES1 101 9
HIPK2 101 1
NEK2a 102 7
IRR 102 1
GSK3 beta 102 7
PKD1 102 4
RSK2 103 19
ERK1 104 11
PKA 104 6
PAK4 104 1
CK2 104 12
p38 beta MAPK 105 6
MST2 106 0
PLK1 107 3
TTK 109 10
MELK 109 2
PAK5 109 1
CAMKK beta 109 0
VEGFR1 116 0
EF2K 123 13
MLK3 126 3
PDK1 128 0
NUAK1 139 11

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