Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
ER-27319 C20H22N2O5 370.40 SYK Moriya K. (1997) Proc. Natl. Acad. Sci. USA 94 12539-12544 Tocris Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
PIM3 43 9
ERK8 54 9
IRR 65 10
PIM1 67 1
CK2 69 5
IR 73 2
MNK1 78 12
MELK 78 4
RSK1 78 6
PKD1 80 17
PKC zeta 81 0
FGF-R1 83 9
CHK2 83 8
ERK1 85 12
p38 beta MAPK 85 7
BRSK2 85 0
PAK4 85 5
EPH-B3 85 4
DYRK1A 85 12
Lck 86 3
DYRK3 87 2
PDK1 87 0
PKC alpha 88 12
BTK 88 11
PHK 89 0
MKK1 89 2
MST4 89 9
SYK 89 4
SGK1 90 3
CDK2-Cyclin A 90 11
Aurora B 90 1
MNK2 90 0
SmMLCK 92 6
Src 92 7
IGF-1R 93 2
p38 delta MAPK 93 7
MAPKAP-K2 93 8
ROCK 2 94 5
PIM2 95 0
SRPK1 95 4
VEGFR1 95 4
IKK beta 96 6
PRK2 96 0
JNK2 96 11
AMPK 96 3
MARK3 96 5
PRAK 96 2
IKK epsilon 96 1
DYRK2 97 9
CHK1 97 6
EPH-A2 97 2
HIPK2 97 20
CAMKK beta 97 0
CAMK1 98 5
TBK1 98 11
JNK1 99 2
RSK2 99 1
PAK6 99 8
CSK 100 10
NEK6 100 0
ERK2 100 4
YES1 100 3
PAK5 100 7
PKB alpha 101 1
MST2 101 1
p38 gamma MAPK 101 5
GSK3 beta 107 1
CK1 delta 107 8
S6K1 109 8
PKA 109 8
p38 alpha MAPK 111 9
MSK1 112 0
PLK1 113 7
PKB beta 117 3
NEK2a 120 12
EF2K 120 1
Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
IR 76 4
MELK 77 2
FGF-R1 79 5
IRR 80 3
p38 beta MAPK 81 10
PIM3 82 1
PKC zeta 83 12
NEK6 84 4
YES1 84 5
PAK5 85 2
BTK 85 7
MNK1 85 12
EPH-B3 86 13
MAPKAP-K2 88 9
TBK1 88 0
PAK4 89 7
SGK1 89 10
p38 delta MAPK 89 11
BRSK2 89 9
ERK8 91 9
CDK2-Cyclin A 91 2
MKK1 92 11
CK2 93 5
Src 93 2
DYRK3 93 5
CHK2 93 14
CHK1 95 9
ERK2 95 7
PKD1 95 10
PRAK 96 5
PKA 96 17
PIM2 96 2
DYRK1A 97 2
CSK 97 5
JNK2 97 10
PIM1 98 0
JNK1 98 0
p38 gamma MAPK 98 7
PAK6 99 0
DYRK2 99 3
EPH-A2 99 4
MST4 99 8
SYK 99 8
HIPK2 99 7
PDK1 100 5
CAMKK beta 100 0
ERK1 100 3
IKK beta 100 10
RSK1 101 1
CAMK1 101 4
IGF-1R 101 19
MNK2 102 10
Aurora B 102 1
MST2 103 2
SmMLCK 105 8
PLK1 105 6
VEGFR1 105 6
MARK3 105 13
Lck 106 8
PHK 106 11
GSK3 beta 106 0
IKK epsilon 107 13
ROCK 2 107 13
PKB alpha 108 12
p38 alpha MAPK 110 0
SRPK1 111 0
RSK2 113 4
PRK2 113 2
AMPK 113 8
PKC alpha 118 27
MSK1 118 0
NEK2a 120 1
CK1 delta 121 1
EF2K 122 0
PKB beta 123 0
S6K1 130 8

Do you need any help? Please get in touch and we’ll be happy to lend a hand.