InhibitorScreening ConcentrationKinase% Activity RemainingStandard Deviation
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMMKK18710
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMMKK28712
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMMKK6945
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMERK110115
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMERK211415
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMJNK11037
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMJNK211315
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMJNK3856
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMp38 alpha MAPK1023
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMp38 beta MAPK1025
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMp38 gamma MAPK915
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMp38 delta MAPK1131
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMERK8343
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMRSK11223
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMRSK21322
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMPDK11032
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMPKB alpha 9910
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMPKB beta 1061
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMSGK19310
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMS6K1981
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMPKA1011
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMROCK 2906
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMPRK2981
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMPKC alpha 1073
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMPKC zeta 12613
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMPKD11095
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMMSK1908
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMMNK1892
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMMNK21057
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMMAPKAP-K2 975
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMMAPKAP-K31097
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMPRAK1104
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMCAMKK beta 1056
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMCAMK1933
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMSmMLCK941
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMPHK1021
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMDAPK1471
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMCHK11189
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMCHK21021
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMGSK3 beta 636
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMCDK2-Cyclin A794
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMPLK18311
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMAurora A1089
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMAurora B813
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMLKB1851
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMAMPK818
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMMARK1990
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMMARK2836
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMMARK310012
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMMARK410612
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMBRSK11387
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMBRSK21151
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMMELK8111
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMNUAK11287
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMCK1 delta 861
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMCK2202
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMDYRK1A273
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMDYRK2161
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMDYRK3183
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMNEK2a1081
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMNEK6937
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMIKK beta 893
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMIKK epsilon 1095
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMTBK110915
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMPIM1703
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMPIM28714
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMPIM3740
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMSRPK11121
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMEF2K1066
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMHIPK1658
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMHIPK2222
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMHIPK3631
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMCLK2737
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMPAK210910
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMPAK41212
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMPAK51032
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMPAK612114
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMMST2932
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMMST41187
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMGCK685
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMMINK1964
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMMEKK110913
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMMLK11264
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMMLK3910
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMTAO1650
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMASK1954
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMTAK110413
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMIRAK4901
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMRIPK28311
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMTTK8311
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMSrc10810
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMLck1002
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMCSK1002
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMYES11008
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMBTK981
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMJAK2992
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMSYK1145
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMEPH-A21260
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMEPH-A41094
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMEPH-B11083
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMEPH-B211110
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMEPH-B31224
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMEPH-B41094
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMFGF-R11026
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMHER4940
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMIGF-1R747
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMIR10010
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMIRR672
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMTrkA1048
Cot-Tpl2 Inhibitor Compound 38 (Abbott)1.00µMVEGFR1967
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMMKK1311
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMMKK2707
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMMKK61004
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMERK1829
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMERK2955
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMJNK11013
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMJNK21005
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMJNK3967
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMp38 alpha MAPK1071
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMp38 beta MAPK1002
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMp38 gamma MAPK7313
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMp38 delta MAPK774
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMERK841
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMRSK1571
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMRSK2886
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMPDK1973
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMPKB alpha 731
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMPKB beta 986
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMSGK1394
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMS6K1505
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMPKA890
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMROCK 29312
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMPRK2545
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMPKC alpha 591
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMPKC zeta 605
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMPKD1953
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMMSK1223
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMMNK1550
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMMNK2641
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMMAPKAP-K2 945
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMMAPKAP-K3956
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMPRAK671
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMCAMKK beta 444
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMCAMK1733
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMSmMLCK425
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMPHK820
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMDAPK1170
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMCHK1655
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMCHK2378
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMGSK3 beta 141
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMCDK2-Cyclin A474
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMPLK1161
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMAurora A632
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMAurora B405
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMLKB1645
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMAMPK511
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMMARK1721
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMMARK2842
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMMARK3513
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMMARK49711
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMBRSK110412
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMBRSK21050
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMMELK197
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMNUAK1884
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMCK1 delta 413
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMCK240
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMDYRK1A51
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMDYRK231
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMDYRK331
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMNEK2a11314
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMNEK68313
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMIKK beta 566
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMIKK epsilon 600
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMTBK1636
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMPIM1171
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMPIM2361
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMPIM3312
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMSRPK11052
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMEF2K806
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMHIPK1121
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMHIPK2112
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMHIPK3100
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMCLK2140
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMPAK21015
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMPAK4975
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMPAK5949
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMPAK61101
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMMST2765
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMMST4715
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMGCK171
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMMINK1873
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMMEKK19310
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMMLK1910
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMMLK36110
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMTAO1302
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMASK1727
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMTAK1676
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMIRAK48812
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMRIPK2307
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMTTK631
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMSrc953
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMLck987
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMCSK956
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMYES1875
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMBTK843
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMJAK2461
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMSYK1029
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMEPH-A2943
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMEPH-A41061
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMEPH-B110012
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMEPH-B21208
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMEPH-B310411
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMEPH-B411010
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMFGF-R1761
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMHER4893
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMIGF-1R743
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMIR911
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMIRR274
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMTrkA711
Cot-Tpl2 Inhibitor Compound 38 (Abbott)10.00µMVEGFR1291