Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
GW501516 C21H18F3NO3S2 453.5 PPARd Sznaidman M.L. (2003) Bioorg Med Chem Lett 13(9) 1517-21 Enzo (Alexis) Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
PRAK 39 5
DYRK1A 59 2
PLK1 60 5
CAMK1 62 13
PKD1 64 1
PAK4 66 4
IGF-1R 67 59
Src 70 0
PIM3 72 2
PDK1 73 2
VEGFR1 74 10
SmMLCK 74 3
JNK1 74 9
PKC zeta 74 3
BRSK2 78 10
MNK1 79 2
CK2 79 10
JNK2 79 14
CK1 delta 80 3
DYRK3 81 7
FGF-R1 81 7
CDK2-Cyclin A 81 7
MNK2 83 19
CAMKK beta 83 0
GSK3 beta 83 12
PIM1 83 5
MST4 83 1
MAPKAP-K2 84 1
MELK 85 2
SYK 85 9
PKA 86 4
SRPK1 87 2
EF2K 88 22
RSK2 88 21
PKC alpha 88 10
TBK1 88 0
MKK1 90 1
AMPK 91 7
MARK3 91 5
ROCK 2 91 12
MSK1 92 7
IKK epsilon 92 1
PRK2 92 5
p38 beta MAPK 94 10
BTK 95 3
IRR 95 12
PHK 96 9
CSK 97 1
Lck 98 7
p38 alpha MAPK 98 2
Aurora B 100 3
CHK2 101 6
ERK2 102 2
YES1 102 3
IR 103 16
PKB beta 103 6
p38 delta MAPK 105 1
PKB alpha 105 9
S6K1 105 16
p38 gamma MAPK 106 8
PIM2 106 2
ERK8 109 8
PAK6 109 6
SGK1 109 13
PAK5 111 5
DYRK2 111 0
RSK1 113 2
EPH-A2 113 5
EPH-B3 115 13
CHK1 120 19
NEK6 120 20
MST2 122 4
ERK1 127 24
IKK beta 139 74
NEK2a 153 0
HIPK2 156 5
Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
PRAK 41 39
PLK1 75 3
PIM1 79 1
PKC zeta 79 11
MELK 79 4
EF2K 80 1
PKD1 81 7
IRR 81 12
CHK2 81 17
p38 alpha MAPK 82 1
CK1 delta 82 12
JNK1 83 11
DYRK3 83 6
VEGFR1 84 1
CK2 84 3
PIM3 86 4
CAMKK beta 86 5
GSK3 beta 87 3
CDK2-Cyclin A 87 14
IGF-1R 87 2
PAK4 87 5
DYRK1A 87 4
Src 87 5
MNK1 89 4
p38 beta MAPK 91 5
BRSK2 91 6
IKK epsilon 92 0
BTK 92 8
SmMLCK 92 1
MARK3 93 9
AMPK 94 8
RSK2 94 3
NEK2a 94 5
CAMK1 95 19
PKC alpha 96 6
SRPK1 96 7
MSK1 96 4
PDK1 96 9
MST2 97 9
MAPKAP-K2 97 12
PAK5 97 0
PAK6 97 0
YES1 98 2
CSK 98 6
S6K1 98 0
ROCK 2 99 18
PIM2 99 17
MNK2 99 4
ERK2 100 1
FGF-R1 100 6
JNK2 101 22
HIPK2 101 2
NEK6 101 3
PRK2 102 5
TBK1 102 8
p38 delta MAPK 102 0
CHK1 102 3
SYK 103 8
ERK8 103 7
DYRK2 103 5
PKB beta 103 10
EPH-A2 103 8
MST4 104 9
MKK1 105 18
RSK1 106 1
Lck 106 2
IR 107 19
PKB alpha 107 7
p38 gamma MAPK 108 14
PHK 109 3
Aurora B 110 10
PKA 110 6
SGK1 111 17
ERK1 115 10
EPH-B3 122 28
IKK beta 220 133

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