Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Caffeine C8H10N4O2 194.19 ATM Islam M.S. (1998) Proc. Natl. Acad. Sci. USA 95 6145-6150 Sigma Download

Results as Barchart

View results as a bar chart
0.1µM
1µM

Results as Table

Screening Concentration: 0.1µM
Kinase % Activity Remainingsort descending Standard Deviation
RSK1 74 7
MKK1 75 27
MARK3 79 7
NEK6 79 14
BTK 79 1
MSK1 80 6
VEGFR1 80 14
DYRK2 81 6
PKB beta 81 4
YES1 85 0
IRR 86 8
CHK2 86 3
IGF-1R 86 0
CDK2-Cyclin A 86 1
IKK epsilon 87 9
MNK2 87 4
p38 alpha MAPK 88 9
p38 delta MAPK 88 1
ERK8 88 16
Lck 88 7
CHK1 88 6
EF2K 88 1
PRK2 89 12
AMPK 90 4
PKB alpha 90 0
CAMK1 90 6
SmMLCK 90 1
IKK beta 90 5
PIM1 90 13
ROCK 2 91 2
Aurora B 91 0
PKD1 92 1
EPH-B3 92 6
TBK1 92 7
DYRK1A 92 7
SYK 92 0
PLK1 92 5
JNK1 92 13
SRPK1 93 5
JNK2 94 1
PKC zeta 95 6
Src 96 2
PRAK 96 0
DYRK3 96 16
EPH-A2 96 4
MST4 96 10
ERK2 96 1
p38 gamma MAPK 97 7
PAK6 97 4
PDK1 97 7
MST2 97 8
MELK 98 3
RSK2 98 12
PAK4 99 6
BRSK2 99 7
PIM3 99 3
ERK1 99 10
CSK 100 3
S6K1 100 10
PKC alpha 101 6
PAK5 102 5
MAPKAP-K2 102 10
SGK1 102 6
GSK3 beta 102 5
PKA 103 2
HIPK2 103 6
CAMKK beta 104 3
IR 104 9
p38 beta MAPK 107 5
NEK2a 107 1
MNK1 110 2
PHK 113 10
PIM2 113 1
CK2 115 4
CK1 delta 118 10
FGF-R1 118 4
Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
MKK1 75 25
JNK1 78 0
BTK 78 4
RSK1 78 2
MARK3 79 19
RSK2 79 8
IRR 80 1
MSK1 82 10
CHK2 83 2
Aurora B 83 3
PKB beta 84 5
VEGFR1 84 17
YES1 85 4
SYK 86 2
PRAK 86 0
DYRK2 87 10
PKC zeta 88 4
p38 delta MAPK 88 2
Src 88 7
NEK6 89 4
PRK2 89 26
p38 alpha MAPK 89 2
MST2 89 19
MAPKAP-K2 89 14
MELK 90 3
IKK epsilon 90 8
SmMLCK 91 15
CDK2-Cyclin A 91 7
MNK2 91 10
Lck 92 2
PKD1 92 18
EF2K 92 5
PDK1 92 1
ROCK 2 93 8
IGF-1R 94 3
PLK1 95 12
ERK8 95 2
CHK1 96 16
PKA 96 2
TBK1 96 8
DYRK1A 96 7
PIM1 97 8
MST4 97 7
PIM3 97 6
SRPK1 97 6
BRSK2 97 4
EPH-B3 97 8
DYRK3 98 1
S6K1 98 3
AMPK 98 2
IR 98 23
MNK1 99 15
IKK beta 100 8
JNK2 100 0
PKC alpha 100 3
PAK4 100 1
PKB alpha 101 7
CAMK1 101 4
ERK2 101 2
GSK3 beta 101 10
PAK6 101 6
NEK2a 102 11
EPH-A2 102 2
CSK 103 13
CAMKK beta 103 1
p38 beta MAPK 104 2
CK2 106 8
p38 gamma MAPK 110 3
FGF-R1 112 15
HIPK2 112 1
ERK1 113 5
PAK5 114 4
PHK 115 12
PIM2 117 21
CK1 delta 120 1
SGK1 121 34

Do you need any help? Please get in touch and we’ll be happy to lend a hand.