InhibitorScreening ConcentrationKinase% Activity RemainingStandard Deviation
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMMKK18512
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMMKK2812
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMMKK61046
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMERK1975
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMERK29611
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMJNK1935
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMJNK29910
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMJNK31054
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMp38 alpha MAPK1062
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMp38 beta MAPK973
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMp38 gamma MAPK868
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMp38 delta MAPK925
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMERK8855
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMRSK1881
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMRSK2772
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMPDK1797
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMPKB alpha 963
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMPKB beta 7714
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMSGK11005
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMS6K1968
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMPKA1081
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMROCK 2735
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMPRK28010
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMPKC alpha 766
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMPKC zeta 1002
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMPKD1892
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMMSK1909
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMMNK11001
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMMNK2940
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMMAPKAP-K2 931
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMMAPKAP-K3824
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMPRAK1044
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMCAMKK beta 848
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMCAMK11058
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMSmMLCK8611
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMPHK1006
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMDAPK1886
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMCHK1794
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMCHK2978
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMGSK3 beta 382
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMCDK2-Cyclin A911
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMPLK1901
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMAurora A1039
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMAurora B847
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMLKB1800
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMAMPK770
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMMARK1891
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMMARK2802
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMMARK3945
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMMARK4860
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMBRSK11105
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMBRSK2926
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMMELK7710
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMNUAK1927
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMCK1 delta 902
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMCK2303
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMDYRK1A218
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMDYRK270
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMDYRK3151
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMNEK2a945
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMNEK69810
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMIKK beta 940
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMIKK epsilon 890
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMTBK1872
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMPIM1707
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMPIM28511
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMPIM3790
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMSRPK1997
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMEF2K10012
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMHIPK11045
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMHIPK2645
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMHIPK3963
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMCLK2803
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMPAK2931
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMPAK48911
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMPAK5812
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMPAK6892
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMMST2984
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMMST4932
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMGCK785
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMMINK1845
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMMEKK1994
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMMLK19510
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMMLK3815
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMTAO1822
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMASK11041
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMTAK1825
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMIRAK4886
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMRIPK2946
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMTTK791
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMSrc852
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMLck1137
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMCSK8612
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMYES19110
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMBTK958
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMJAK2974
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMSYK1075
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMEPH-A2948
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMEPH-A41035
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMEPH-B19510
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMEPH-B21066
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMEPH-B3933
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMEPH-B4970
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMFGF-R11050
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMHER48811
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMIGF-1R10715
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMIR11110
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMIRR790
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMTrkA836
Cot-Tpl2 Inhibitor Compound 41 (Abbott)1.00µMVEGFR18414
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMMKK1787
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMMKK2752
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMMKK6999
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMERK1781
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMERK29615
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMJNK1779
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMJNK2853
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMJNK3726
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMp38 alpha MAPK9811
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMp38 beta MAPK1046
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMp38 gamma MAPK657
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMp38 delta MAPK546
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMERK820
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMRSK1337
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMRSK2445
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMPDK19112
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMPKB alpha 781
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMPKB beta 622
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMSGK1682
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMS6K16413
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMPKA721
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMROCK 2380
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMPRK25315
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMPKC alpha 301
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMPKC zeta 675
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMPKD1806
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMMSK1201
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMMNK1846
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMMNK2586
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMMAPKAP-K2 851
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMMAPKAP-K3870
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMPRAK561
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMCAMKK beta 232
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMCAMK1856
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMSmMLCK355
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMPHK841
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMDAPK1182
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMCHK1872
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMCHK2590
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMGSK3 beta 102
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMCDK2-Cyclin A1052
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMPLK1243
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMAurora A781
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMAurora B582
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMLKB1594
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMAMPK494
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMMARK1781
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMMARK2837
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMMARK3716
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMMARK4783
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMBRSK1908
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMBRSK2953
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMMELK621
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMNUAK1781
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMCK1 delta 595
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMCK261
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMDYRK1A31
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMDYRK220
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMDYRK362
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMNEK2a809
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMNEK6946
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMIKK beta 641
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMIKK epsilon 692
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMTBK16311
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMPIM1185
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMPIM2140
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMPIM3214
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMSRPK1486
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMEF2K1019
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMHIPK192
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMHIPK21010
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMHIPK3100
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMCLK2121
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMPAK2907
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMPAK4543
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMPAK5666
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMPAK6873
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMMST2750
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMMST4616
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMGCK131
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMMINK1212
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMMEKK1517
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMMLK1421
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMMLK3250
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMTAO1360
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMASK11121
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMTAK17511
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMIRAK4742
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMRIPK2221
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMTTK515
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMSrc922
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMLck998
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMCSK1004
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMYES1871
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMBTK717
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMJAK2740
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMSYK953
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMEPH-A2894
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMEPH-A41129
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMEPH-B11076
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMEPH-B2998
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMEPH-B39612
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMEPH-B4963
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMFGF-R1616
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMHER4734
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMIGF-1R9511
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMIR1084
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMIRR266
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMTrkA896
Cot-Tpl2 Inhibitor Compound 41 (Abbott)10.00µMVEGFR1246