Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Zearalenone C18H22O5 318.4 Estrogen receptor (ER) Powell-Jones W. (1981) Mol. Pharmacol. 20 35-42 Sigma Download

Results as Barchart

View results as a bar chart
10µM
1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 66 4
ERK1 113 10
ERK2 98 3
JNK1 88 5
JNK2 46 2
p38 alpha MAPK 93 8
p38 beta MAPK 108 11
p38 gamma MAPK 97 4
p38 delta MAPK 84 1
ERK8 77 13
RSK1 89 1
RSK2 80 13
PDK1 91 5
PKB alpha 111 23
PKB beta 97 4
SGK1 93 6
S6K1 106 18
PKA 97 7
ROCK 2 82 5
PRK2 70 5
PKC alpha 54 4
PKC zeta 98 10
PKD1 86 1
MSK1 69 29
MNK1 89 15
MNK2 64 4
MAPKAP-K2 101 7
PRAK 97 5
CAMKK beta 90 5
CAMK1 101 1
SmMLCK 104 11
PHK 102 6
CHK1 92 5
CHK2 93 3
GSK3 beta 47 3
CDK2-Cyclin A 82 10
PLK1 76 5
Aurora B 37 1
AMPK 94 13
MARK3 102 4
BRSK2 54 1
MELK 97 6
CK1 delta 99 4
CK2 97 15
DYRK1A 72 22
DYRK2 90 3
DYRK3 100 3
NEK2a 93 9
NEK6 91 1
IKK beta 101 12
IKK epsilon 95 5
TBK1 82 5
PIM1 51 6
PIM2 86 2
PIM3 49 3
SRPK1 95 19
EF2K 101 3
HIPK2 100 0
PAK4 95 6
PAK5 93 11
PAK6 99 10
MST2 119 2
MST4 103 25
Src 89 13
Lck 69 2
CSK 80 6
YES1 79 8
BTK 107 12
SYK 93 12
EPH-A2 69 4
EPH-B3 85 11
FGF-R1 90 16
IGF-1R 93 13
IR 107 13
IRR 75 18
VEGFR1 95 8
Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 55 0
ERK1 107 7
ERK2 96 17
JNK1 80 2
JNK2 65 9
p38 alpha MAPK 85 2
p38 beta MAPK 101 2
p38 gamma MAPK 93 10
p38 delta MAPK 87 2
ERK8 26 5
RSK1 41 1
RSK2 52 3
PDK1 80 2
PKB alpha 95 9
PKB beta 89 4
SGK1 93 13
S6K1 61 9
PKA 91 5
ROCK 2 81 4
PRK2 33 5
PKC alpha 69 2
PKC zeta 86 9
PKD1 64 17
MSK1 36 2
MNK1 46 5
MNK2 23 1
MAPKAP-K2 92 1
PRAK 79 4
CAMKK beta 52 3
CAMK1 75 11
SmMLCK 59 1
PHK 86 5
CHK1 81 5
CHK2 73 7
GSK3 beta 11 1
CDK2-Cyclin A 32 1
PLK1 63 5
Aurora B 23 4
AMPK 60 9
MARK3 99 4
BRSK2 17 1
MELK 66 0
CK1 delta 83 3
CK2 96 5
DYRK1A 32 8
DYRK2 62 1
DYRK3 62 4
NEK2a 96 11
NEK6 91 3
IKK beta 78 15
IKK epsilon 82 5
TBK1 80 4
PIM1 11 0
PIM2 45 11
PIM3 18 2
SRPK1 89 17
EF2K 85 15
HIPK2 63 6
PAK4 90 2
PAK5 80 6
PAK6 94 10
MST2 113 12
MST4 66 9
Src 34 5
Lck 26 0
CSK 64 5
YES1 35 1
BTK 69 3
SYK 84 6
EPH-A2 26 1
EPH-B3 85 3
FGF-R1 51 4
IGF-1R 64 6
IR 102 3
IRR 41 1
VEGFR1 69 10

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