Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Y-27632 C14H21N3O • 2HCl • H2O 338.3 ROCK Watanabe K. (2007) Nature Biotech. 25 681 Chitaley K. (2001) Nat. Med. 7 119 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 96 1
ERK1 98 0
ERK2 82 7
JNK1 79 8
JNK2 90 4
JNK3 92 0
p38 alpha MAPK 105 4
p38 beta MAPK 108 3
p38 gamma MAPK 102 1
p38 delta MAPK 87 4
ERK8 94 1
RSK1 21 1
RSK2 43 7
PDK1 74 0
PKB alpha 73 2
PKB beta 86 0
SGK1 72 4
S6K1 93 0
PKA 72 1
ROCK 2 7 0
PRK2 3 2
PKC alpha 57 1
PKC zeta 55 7
PKD1 85 3
MSK1 27 2
MNK1 25 2
MNK2 54 2
MAPKAP-K2 91 2
MAPKAP-K3 99 5
PRAK 78 2
CAMKK alpha 107 6
CAMKK beta 75 5
CAMK1 98 6
SmMLCK 91 7
PHK 49 5
CHK1 72 0
CHK2 100 1
GSK3 beta 86 3
CDK2-Cyclin A 50 1
PLK1 78 3
Aurora B 79 7
Aurora C 65 0
LKB1 51 12
AMPK 14 1
MARK3 69 3
BRSK2 57 4
MELK 64 0
NUAK1 106 0
CK1 delta 93 3
CK2 89 8
DYRK1A 81 5
DYRK2 86 4
DYRK3 89 9
NEK2a 85 5
NEK6 91 9
NEK7 102 5
IKK beta 78 1
IKK epsilon 76 8
TBK1 69 8
PIM1 87 0
PIM2 91 2
PIM3 56 1
SRPK1 87 5
EF2K 85 4
HIPK2 83 4
HIPK3 97 2
PAK4 89 2
PAK5 89 3
PAK6 88 2
MST2 46 3
MST4 67 7
GCK 89 4
MINK1 80 0
MLK1 89 18
MLK3 109 3
IRAK4 100 7
TTK 73 2
Src 79 4
Lck 73 4
CSK 69 2
YES1 96 4
BTK 85 17
SYK 93 8
EPH-A2 106 3
EPH-B3 83 12
FGF-R1 94 9
HER4 68 8
IGF-1R 98 5
IR 112 1
IRR 90 0
VEGFR1 105 3

Do you need any help? Please get in touch and we’ll be happy to lend a hand.