Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
SU-6668 C18H18N2O3 310.35 Aurora Godl K. (2005) Cancer Res. 65 6919-6926. Tocris Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 10 1
ERK1 75 4
ERK2 82 13
JNK1 94 9
JNK2 98 1
JNK3 86 0
p38 alpha MAPK 114 5
p38 beta MAPK 101 6
p38 gamma MAPK 85 13
p38 delta MAPK 104 5
ERK8 6 0
RSK1 4 1
RSK2 11 1
PDK1 11 1
PKB alpha 106 3
PKB beta 84 9
SGK1 40 8
S6K1 2 0
PKA 49 0
ROCK 2 10 0
PRK2 20 0
PKC alpha 62 3
PKC zeta 103 2
PKD1 44 1
MSK1 27 0
MNK1 40 4
MNK2 68 7
MAPKAP-K2 89 2
MAPKAP-K3 103 9
PRAK 43 2
CAMKK beta 28 11
CAMK1 41 1
SmMLCK 59 1
PHK 5 1
CHK1 8 0
CHK2 4 0
GSK3 beta 34 2
CDK2-Cyclin A 45 1
PLK1 56 6
Aurora B 2 0
Aurora C 1 0
AMPK 8 0
MARK3 12 0
BRSK2 5 1
MELK 19 0
CK1 delta 10 0
CK2 50 10
DYRK1A 55 9
DYRK2 50 1
DYRK3 64 4
NEK2a 44 0
NEK6 95 5
NEK7 94 10
IKK beta 42 2
IKK epsilon 8 0
TBK1 4 2
PIM1 70 1
PIM2 91 3
PIM3 14 1
SRPK1 15 1
EF2K 86 8
HIPK2 25 1
HIPK3 61 4
PAK4 31 1
PAK5 50 0
PAK6 84 1
MST2 4 3
MST4 50 11
Src 27 5
Lck 34 1
CSK 115 3
YES1 9 1
SYK 79 6
EPH-A2 95 4
FGF-R1 8 0
IRR 27 5
Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 31 1
ERK1 85 3
ERK2 92 3
JNK1 99 14
JNK2 99 3
JNK3 90 10
p38 alpha MAPK 95 6
p38 beta MAPK 78 5
p38 gamma MAPK 84 2
p38 delta MAPK 88 9
ERK8 51 1
RSK1 55 7
RSK2 50 3
PDK1 73 7
PKB alpha 93 11
PKB beta 95 1
SGK1 80 3
S6K1 47 4
PKA 102 10
ROCK 2 68 5
PRK2 73 3
PKC alpha 87 2
PKC zeta 97 1
PKD1 82 5
MSK1 74 13
MNK1 83 2
MNK2 89 6
MAPKAP-K2 104 8
MAPKAP-K3 103 7
PRAK 86 13
CAMKK alpha 55 5
CAMKK beta 61 2
CAMK1 76 7
SmMLCK 61 5
PHK 48 7
CHK1 63 1
CHK2 16 0
GSK3 beta 83 8
CDK2-Cyclin A 87 6
PLK1 83 1
Aurora B 3 0
Aurora C 10 0
AMPK 52 5
MARK3 70 6
BRSK2 53 2
MELK 84 6
CK1 delta 57 6
CK2 82 8
DYRK1A 90 7
DYRK2 96 12
DYRK3 95 8
NEK2a 87 2
NEK6 98 5
NEK7 99 9
IKK beta 90 8
IKK epsilon 51 8
TBK1 34 4
PIM1 90 7
PIM2 111 12
PIM3 66 7
SRPK1 67 2
EF2K 95 9
HIPK2 68 1
HIPK3 95 0
PAK4 79 7
PAK5 88 6
PAK6 87 4
MST2 53 3
MST4 113 5
Src 85 1
Lck 82 5
CSK 93 8
YES1 89 0
SYK 81 6
EPH-A2 98 5
FGF-R1 69 8
IRR 87 4

Do you need any help? Please get in touch and we’ll be happy to lend a hand.