Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
SU-6656 C19H21N3O3S 371.5 Src Bowman T. (2001) Proc. Natl. Acad. Sci. USA 98 7319 Blake R.A. (2000) Mol. Cell. Biol. 20 9018 Sigma Download

Results as Barchart

View results as a bar chart
10µM
1µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
JAK2 0 2
IRAK1 1 1
Aurora B 2 0
ULK1 2 1
Aurora A 3 2
MAP4K3 3 1
AMPK (hum) 3 3
YES1 3 1
MAP4K5 4 0
TrkA 5 2
MST2 6 2
NUAK1 6 0
GCK 6 1
SRPK1 6 1
BRSK2 6 2
IRAK4 6 1
ULK2 7 7
CLK2 7 1
CAMKK beta 9 1
AMPK 10 2
Src 11 4
CHK2 11 3
Lck 12 2
BRSK1 18 2
ROCK 2 19 3
VEGFR1 19 6
IKK epsilon 21 2
FGF-R1 21 0
PRK2 21 2
MARK4 21 0
MST3 23 2
STK33 23 2
DDR2 24 2
MLK3 25 3
RSK1 27 2
MKK1 28 2
ERK8 29 3
IR 29 16
DYRK1A 30 7
PDGFRA 31 7
ABL 36 5
PAK4 36 1
MINK1 37 8
EPH-B3 37 2
MARK3 38 3
EPH-A2 41 0
EPH-A4 41 6
EPH-B2 41 4
MKK2 41 7
TTK 44 7
CSK 44 10
SYK 44 5
MLK1 45 8
RIPK2 48 2
TAO1 50 15
OSR1 51 5
MST4 51 48
SIK3 51 0
TSSK1 51 14
TESK1 51 7
PHK 51 8
MARK1 53 31
BTK 53 5
CHK1 55 10
TBK1 56 8
TAK1 56 6
NEK2a 57 14
IRR 59 3
IGF-1R 60 30
SIK2 62 1
RSK2 62 0
PRAK 62 2
S6K1 63 10
BRK 64 12
MAPKAP-K3 64 1
CDK9-Cyclin T1 65 10
HIPK2 66 9
ASK1 66 4
CDK2-Cyclin A 68 39
SGK1 69 15
SmMLCK 69 1
TIE2 74 3
CK1 delta 74 4
MEKK1 75 12
MARK2 75 23
GSK3 beta 76 20
EPH-B4 76 20
ERK2 76 11
EF2K 77 12
CAMK1 78 3
PKB beta 79 23
p38 beta MAPK 80 5
MELK 80 10
NEK6 80 5
p38 alpha MAPK 80 0
MKK6 82 9
PKA 82 1
MSK1 83 8
DAPK1 83 7
PIM3 84 11
DYRK3 85 14
JNK3 85 1
DYRK2 87 2
IKK beta 87 9
p38 delta MAPK 88 6
EPH-B1 89 3
MNK2 89 10
HIPK1 90 8
HER4 90 5
PAK2 90 2
JNK2 90 2
PDK1 91 3
TTBK1 91 7
PIM2 94 1
PKB alpha 94 1
CK2 94 11
ERK1 94 12
PKC alpha 95 1
PAK5 95 11
PKC gamma 95 1
TLK1 96 11
LKB1 96 16
MPSK1 98 3
WNK1 98 8
PKC zeta 100 3
MNK1 100 7
CK1 gamma 2 100 10
p38 gamma MAPK 102 5
MAPKAP-K2 102 16
EIF2AK3 102 8
JNK1 103 15
PAK6 103 28
ZAP70 103 3
PIM1 104 5
HIPK3 107 6
PKD1 108 14
TTBK2 112 22
PLK1 114 11
Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
MAP4K3 1 0
ULK1 1 1
JAK2 2 4
IRAK1 2 0
Aurora A 2 1
Aurora B 3 0
YES1 3 0
MAP4K5 4 0
AMPK (hum) 4 1
CLK2 5 1
Aurora C 7 0
MST2 7 1
GCK 7 0
ULK2 8 1
IRAK4 10 4
Src 12 4
CAMKK beta 12 4
Lck 12 0
BRSK1 13 1
BRSK2 13 1
CHK2 14 1
AMPK 17 0
SRPK1 19 5
CAMKK alpha 20 4
MST4 21 2
PRK2 26 3
BRK 26 5
STK33 30 1
DDR2 31 1
MLK3 32 5
ABL 32 3
MLK1 33 6
IKK epsilon 33 0
IR 35 6
MARK3 35 4
FGF-R1 37 4
MARK2 37 0
MKK1 38 11
RSK1 38 9
MST3 42 1
MARK1 45 18
DYRK1A 45 4
ROCK 2 46 2
CHK1 49 3
TrkA 49 66
TSSK1 50 23
TESK1 51 11
RIPK2 51 2
PHK 52 6
MARK4 53 1
SIK3 54 12
TAK1 55 6
MKK2 56 4
NUAK1 56 75
MINK1 58 34
TTK 58 2
SIK2 59 3
TAO1 60 2
BTK 62 9
VEGFR1 64 58
EPH-A4 64 12
PIM3 65 0
ERK8 65 4
NEK2a 66 2
TBK1 66 3
RSK2 66 11
EPH-B4 70 6
SYK 71 8
TIE2 71 14
MEKK1 72 3
HIPK2 72 12
PAK4 73 1
TTBK2 74 17
OSR1 74 0
ERK2 75 6
PAK5 75 2
EPH-A2 75 6
HER4 76 31
EPH-B3 77 5
S6K1 78 1
LKB1 79 10
SmMLCK 79 2
MELK 79 5
IRR 80 39
PAK6 80 0
PRAK 83 15
JNK1 83 9
CSK 85 1
p38 alpha MAPK 85 2
MAPKAP-K3 86 12
ASK1 86 3
DYRK3 87 1
DYRK2 88 7
p38 beta MAPK 88 7
GSK3 beta 88 6
PKA 89 4
IKK beta 89 13
p38 delta MAPK 89 7
EPH-B1 90 1
EPH-B2 91 2
EF2K 91 7
TTBK1 91 9
JNK2 91 3
SGK1 92 15
CDK2-Cyclin A 92 0
MKK6 93 12
CK2 93 1
ERK1 95 10
DAPK1 95 10
MPSK1 95 2
IGF-1R 96 25
MNK2 97 2
MSK1 98 5
PAK2 99 3
TLK1 101 12
EIF2AK3 101 0
CAMK1 101 2
PKC gamma 101 4
p38 gamma MAPK 101 9
CDK9-Cyclin T1 101 9
MAPKAP-K2 102 10
PKB alpha 102 4
HIPK1 102 6
PKD1 102 4
ZAP70 102 1
PKB beta 103 14
PDK1 104 20
WNK1 104 5
CK1 delta 104 6
JNK3 104 7
PLK1 105 5
PKC alpha 106 15
NEK6 106 8
PIM2 106 6
CK1 gamma 2 109 3
MNK1 111 6
PIM1 112 1
PKC zeta 114 3
HIPK3 118 15

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