Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
SRC Inhibitor 1 C22H19N3O3 373.4 Src Tian G. (2001) Biochemistry 40 7084 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 50 8
ERK1 103 8
ERK2 74 9
JNK1 84 3
JNK2 94 9
JNK3 81 7
p38 alpha MAPK 83 4
p38 beta MAPK 90 8
p38 gamma MAPK 104 2
p38 delta MAPK 86 2
ERK8 82 7
RSK1 73 5
RSK2 80 2
PDK1 88 3
PKB alpha 80 12
PKB beta 86 7
SGK1 106 4
S6K1 92 4
PKA 95 9
ROCK 2 84 10
PRK2 81 4
PKC alpha 95 2
PKC zeta 95 4
PKD1 81 4
MSK1 81 3
MNK1 81 1
MNK2 61 7
MAPKAP-K2 81 3
MAPKAP-K3 88 4
PRAK 94 5
CAMKK beta 94 1
CAMK1 86 9
SmMLCK 85 14
PHK 80 5
CHK1 86 8
CHK2 11 1
GSK3 beta 89 1
CDK2-Cyclin A 97 13
PLK1 95 13
Aurora B 35 1
Aurora C 71 1
AMPK 87 11
MARK3 92 10
BRSK2 92 11
MELK 76 7
CK1 delta 101 4
CK2 92 2
DYRK1A 102 5
DYRK2 100 1
DYRK3 81 2
NEK2a 83 1
NEK6 97 14
NEK7 81 7
IKK beta 97 7
IKK epsilon 81 12
TBK1 93 15
PIM1 82 0
PIM2 85 6
PIM3 81 8
SRPK1 69 0
EF2K 89 1
HIPK2 88 1
HIPK3 83 13
PAK4 95 1
PAK5 81 2
PAK6 102 12
MST2 87 4
MST4 72 7
Src 12 1
Lck 11 1
CSK 12 3
YES1 5 1
SYK 91 5
EPH-A2 85 9
FGF-R1 40 7
IRR 108 5
Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 25 3
ERK1 103 7
ERK2 68 7
JNK1 75 0
JNK2 77 7
JNK3 74 13
p38 alpha MAPK 82 2
p38 beta MAPK 67 7
p38 gamma MAPK 96 1
p38 delta MAPK 70 4
ERK8 80 1
RSK1 41 3
RSK2 81 7
PDK1 89 7
PKB alpha 91 6
PKB beta 88 14
SGK1 94 4
S6K1 77 10
PKA 94 10
ROCK 2 71 15
PRK2 75 10
PKC alpha 87 9
PKC zeta 89 2
PKD1 91 6
MSK1 75 9
MNK1 61 2
MNK2 50 1
MAPKAP-K2 81 5
MAPKAP-K3 100 6
PRAK 89 6
CAMKK beta 93 0
CAMK1 61 10
SmMLCK 49 0
PHK 70 3
CHK1 84 4
CHK2 2 1
GSK3 beta 74 14
CDK2-Cyclin A 103 14
PLK1 87 1
Aurora B 23 2
Aurora C 42 5
AMPK 74 4
MARK3 102 3
BRSK2 88 6
MELK 74 6
CK1 delta 81 5
CK2 105 3
DYRK1A 95 0
DYRK2 94 14
DYRK3 68 11
NEK2a 70 7
NEK6 96 4
NEK7 87 9
IKK beta 98 1
IKK epsilon 81 9
TBK1 75 8
PIM1 86 11
PIM2 95 6
PIM3 69 7
SRPK1 66 11
EF2K 111 7
HIPK2 79 8
HIPK3 84 5
PAK4 52 2
PAK5 65 5
PAK6 82 6
MST2 72 10
MST4 70 11
Src 2 0
Lck 4 0
CSK 2 0
YES1 1 0
SYK 86 4
EPH-A2 103 4
FGF-R1 20 5
IRR 101 10

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