Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
SP600125 (JNK Inhibitor II, SAPK Inhibitor II) C14H8N2O 220.2 JNK Shin M. Boyd Y.D. (2002) Biochim. Biophys. Acta 1589 311 Bennett B.L. (2001) Proc. Natl. Acad. Sci. USA 98 13681 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
Aurora B 14 0
MELK 14 3
CK1 delta 15 0
PIM3 17 0
DYRK2 18 1
Aurora C 20 2
JNK1 22 1
JNK2 24 2
PKD1 25 0
SGK1 27 0
PHK 30 0
DYRK3 30 7
MST2 31 4
HIPK2 34 7
SmMLCK 34 4
PIM1 39 2
CAMKK beta 40 3
DYRK1A 40 1
ERK8 42 1
BRSK2 43 8
AMPK 44 4
CHK2 44 4
JNK3 47 0
IKK beta 48 3
MARK3 49 5
CDK2-Cyclin A 49 1
RSK1 55 0
PDK1 55 5
HIPK3 55 4
PIM2 57 2
CK2 57 4
MNK2 58 4
PRAK 58 8
MKK1 58 7
PAK4 60 3
CHK1 62 2
CSK 64 4
MNK1 67 3
Lck 67 2
PKC alpha 67 5
CAMKK alpha 68 7
RSK2 69 1
PRK2 70 5
PAK6 71 5
MSK1 72 9
CAMK1 73 1
NEK2a 77 1
PKA 79 5
PLK1 80 2
PAK5 81 0
GSK3 beta 81 4
p38 delta MAPK 82 2
SRPK1 83 4
S6K1 84 1
p38 gamma MAPK 85 1
ERK2 85 2
ERK1 88 4
Src 88 1
ROCK 2 91 2
PKB beta 92 1
PKB alpha 97 1
MAPKAP-K2 102 2
NEK6 102 4
MAPKAP-K3 103 0
p38 beta MAPK 106 1
PKC zeta 106 2
p38 alpha MAPK 109 2
NEK7 112 6
EF2K 118 1

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